Navigation Links
Brain signs of schizophrenia found in babies

CHAPEL HILL Schizophrenia is a debilitating mental disorder affecting one in 100 people worldwide. Most cases aren't detected until a person starts experiencing symptoms like delusions and hallucinations as a teenager or adult. By that time, the disease has often progressed so far that it can be difficult to treat.

In a paper published recently online by the American Journal of Psychiatry, researchers at the University of North Carolina at Chapel Hill and Columbia University provide the first evidence that brain abnormalities associated with schizophrenia risk are detectable in babies only a few weeks old.

"It allows us to start thinking about how we can identify kids at risk for schizophrenia very early and whether there things that we can do very early on to lessen the risk," said lead study author John H. Gilmore, MD, professor of psychiatry and director of the UNC Schizophrenia Research Center.

The scientists used ultrasound and MRI to examine brain development in 26 babies born to mothers with schizophrenia. Having a first-degree relative with the disease raises a person's risk of schizophrenia to one in 10. Among boys, the high-risk babies had larger brains and larger lateral ventriclesfluid-filled spaces in the brainthan babies of mothers with no psychiatric illness.

"Could it be that enlargement is an early marker of a brain that's going to be different?" Gilmore speculated. Larger brain size in infants is also associated with autism.

The researchers found no difference in brain size among girls in the study. This fits the overall pattern of schizophrenia, which is more common, and often more severe, in males.

The findings do not necessarily mean the boys with larger brains will develop schizophrenia. Relatives of people with schizophrenia sometimes have subtle brain abnormalities but exhibit few or no symptoms.

"This is just the very beginning," said Gilmore. "We're following these children through childhood." The team will continue to measure the children's brains and will also track their language skills, motor skills and memory development. They will also continue to recruit women to the study to increase the sample size.

This research provides the first indication that brain abnormalities associated with schizophrenia can be detected early in life. Improving early detection could allow doctors to develop new approaches to prevent high-risk children from developing the disease. "The research will give us a better sense of when brain development becomes different," said Gilmore. "And that will help us target interventions."


Contact: Les Lang
University of North Carolina School of Medicine

Related medicine news :

1. 3-D Brain Navigation, Minimally Invasive Surgery Combine to Help Neurosurgeon Remove Tennis Ball-Sized Tumor
2. Reinvent your Mental State With Brainwave Entrainment Relaxation Music
3. Awake sedation for brain surgery may shorten hospital stay
4. Chopra Center Co-Founder and Mind-body Healing Pioneer David Simon, M.D. Diagnosed with Brain Tumor
5. Shared Opinions Light Up Brains Reward Center
6. Brain Circuitry May Develop Through Adulthood
7. UCLA scientists teach cultured brain cells to keep time
8. Brain Academy's Revolutionary New Approach to Tutoring and Test Prep Helps Students Find Academic Success
9. Harmless Brain Abnormalities in Kids Pose Disclosure Dilemmas
10. Brain MRI in children: Incidental findings yield disclosure dilemmas for doctors, patients
11. NYUs Movshon receives Champalimaud Vision Award for work on how brain reconstructs images
Post Your Comments:
Related Image:
Brain signs of schizophrenia found in babies
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
Breaking Medicine Technology: