Navigation Links
Brain connectivity disrupted in patients with post-concussive syndrome
Date:7/25/2011

cluding traumatic brain injury," Dr. Ge said.

Resting-state functional MRI (RS-fMRI) has rapidly emerged as a novel informative tool for investigating brain connectivity between regions that are functionally linked. RS-fMRI provides insight into functional activity and communication between brain regions, which play key roles in cognitive performance.

"The disruption of such functional properties is better characterized by RS-fMRI than by conventional diagnostic tools," Dr. Ge said.

Dr. Ge and colleagues used RS-fMRI to study the brain activity of 24 patients with MTBI and 17 healthy control patients. A normal pattern of thalamic RSNs with relatively symmetric and restrictive connectivity was demonstrated in the healthy control group. In the patients with MTBI, this pattern was disrupted, with significantly increased thalamic RSNs and decreased symmetry. These findings correlated with clinical symptoms and diminished neurocognitive functions in the patients with MTBI.

"The thalamic functional networks have multiple functions, including sensory information process and relay, consciousness, cognition, and sleep and wakefulness regulation," Dr. Ge said. "The disruption of thalamic RSNs may result in a burning or aching sensation, accompanied by mood swings and sleep disorders, and can contribute to certain psychotic, affective, obsessive-compulsive, anxiety and impulse control disorders. These symptoms are commonly seen in MTBI patients with post-concussive syndrome."

Because the causes of post-concussive syndrome are poorly understood, there is currently no treatment. But, according to Dr. Ge, the results of this study have implications for a new therapeutic strategy, based on sound understanding of the underlying mechanisms of thalamocortical disruption and post-concussive syndrome.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Gadgets not related to teenagers brain pain
2. Dementia Rates Escalate as Brain Capacity Diminishes with Age
3. Researchers discover new way to kill pediatric brain tumors
4. Scientists Pinpoint Area of Brain That Fears Losing Money
5. Physical Changes in Brain Linked to Altered Spirituality
6. Pro Athletes Brains React at Olympic Speed
7. Neuroscientists reveal new links that regulate brain electrical activity
8. Brain Scan Shows What Beauty is Worth
9. Study supports alternative anti-seizure medication following acute brain injury
10. Exercise helps protect brain of multiple sclerosis patients
11. Pittsburgh Neurosurgeons Explore Use of Drug that Illuminates Brain Tumor Cells To Guide Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... Mich (PRWEB) , ... August 03, 2015 , ... Since ... country has declined, according to a new publication released today by the AAMC (Association ... black male college graduates over the past three decades, the number of black male ...
(Date:8/3/2015)... ... ... to an opinion piece published July 28 by the Washington Post, the conventional ... loss may not be accurate. While this system may work for some people, the author ... based both on the individual and at what point that person is in their weight ...
(Date:8/3/2015)... ... August 03, 2015 , ... BESLER Consulting today ... B2B Awards. , The MarketingProfs Bright Bulb B2B Awards celebrate the best marketing, ... for the launch of their Readmissions Analytics product was selected as one of ...
(Date:8/3/2015)... CA (PRWEB) , ... August 03, 2015 , ... ... Hispanic Health notes that while an overwhelming number of Hispanics believe people ... , The overwhelming 70 percent of participants queried said making diet changes was ...
(Date:8/3/2015)... ... August 03, 2015 , ... Social ... , AUGUST 3, 2015 – Since winning a South by Southwest® (SXSW®) Interactive ... – an organization whose mission is to develop technology for the sake of ...
Breaking Medicine News(10 mins):Health News:New Publication Focuses on the Decline of Black Males in Medicine 2Health News:New Publication Focuses on the Decline of Black Males in Medicine 3Health News:New Publication Focuses on the Decline of Black Males in Medicine 4Health News:Article Dispelling Weight Loss Myth Correctly Emphasizes the Complicated and Difficult Nature of Weight Loss, Says Dr. Michael Feiz 2Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 2Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 3Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 4Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 2Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 3Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 4
... crisis in the 1990s the hole in Earth,s ... acid rain worse, scientists are reporting. Their ... (CFCs) once used in aerosol spray cans, air conditioners, ... Physical Chemistry A, a weekly publication. Jeffrey Gaffney, ...
... Comparing tuition and ... and intimidating for adults going back to school. Try comparing hundreds to find the ... service is about to change all that. , ... Tampa, Florida (PRWEB) June 16, 2010 -- Comparing tuition and fees between ...
... Alcohol consumption is associated with a significantly ... Rheumatoid Arthritis (RA), Osteoarthritis (OA), reactive arthritis, psoriatic ... new study presented today at EULAR 2010, the ... in Rome, Italy. Regardless of the type of ...
... international team of researchers led by scientists at the Virginia ... of an Amerindian strain of the gastric bug Helicobacter ... to the New World. Experiments in animals have highlighted how ... the onset of inflammation and disease. H. ...
... head injury guidelines for school sports, survey shows , ... strict policies on concussions in school sports, the majority ... -- and most report widespread pressure to return young ... These findings came from the C.S. Mott Children,s Hospital ...
... creates sense of connectedness, research shows , WEDNESDAY, June 16 (HealthDay ... team take on Slovenia in its next World Cup match on ... than just a lot of fun. , Scientists have shown that ... who attend games and cheer along with like-minded fans, reap the ...
Cached Medicine News:Health News:Comparing Tuition and Fees Just Got Easier With College Equalizer, the New Revolutionary College Search System Set to Launch Soon 2Health News:Comparing Tuition and Fees Just Got Easier With College Equalizer, the New Revolutionary College Search System Set to Launch Soon 3Health News:Alcohol consumption lowers risk of developing several arthritic conditions 2Health News:New world Helicobacter pylori genome sequenced, dynamics of inflammation-related genes revealed 2Health News:Parents Ill-Informed About Kids' Concussion Risks 2Health News:World Cup Matches Might Boost Your Mental Health 2Health News:World Cup Matches Might Boost Your Mental Health 3Health News:World Cup Matches Might Boost Your Mental Health 4
(Date:8/3/2015)...  Array BioPharma Inc. (NASDAQ: ARRY ) ... full year of its fiscal year ended June ... of Array, noted, "Binimetinib and encorafenib, two innovative ... for regulatory submissions in 2016. Additional data shared ... colorectal cancer further validate the value of these ...
(Date:8/3/2015)... YORK , Aug. 3, 2015 Immune ... Immune,s CEO, Dr. Daniel Teper , will present ... DATE:  Thursday, August 6, 2015 TIME:   11:30AM EDT LINK:    ... a live, interactive online event where investors are invited ... in the presentation hall as well as the association,s ...
(Date:8/3/2015)... Aug. 3, 2015  Sorrento Therapeutics, Inc. (NASDAQ: ... into an exclusive licensing agreement to develop and commercialize ... Mabtech Limited, a holding company for premier antibody development ... Under the terms of the agreement, ... (mAbs) for the North American, European and Japanese market. ...
Breaking Medicine Technology:Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 2Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 3Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 4Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 5Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 6Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 7Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 8Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 9Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 10Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 11Array BioPharma Reports Financial Results For The Fourth Quarter And Full Year Of Fiscal 2015 12Immune Pharmaceuticals to Webcast Live at VirtualInvestorConferences.com August 6 2Sorrento In-Licenses Four Late-Stage Clinical Biobetter and Biosimilar Antibodies 2Sorrento In-Licenses Four Late-Stage Clinical Biobetter and Biosimilar Antibodies 3Sorrento In-Licenses Four Late-Stage Clinical Biobetter and Biosimilar Antibodies 4
... ROCKVILLE, Md., Oct. 5 Sequella, Inc., a clinical-stage ... life-threatening infectious diseases, today announced that it received a ... and Reinvestment Act (ARRA) of 2009. The ARRA funds, ... Diseases (NIAID) of the National Institute of Health (NIH), ...
... First Recipient of adjunctive screening system , NEWPORT BEACH, ... initiated a program of donating VELscope® Oral Cancer Screening ... helping communities with, underserved populations. The first recipient ... Center, commonly known as Native Heath, in Phoenix, Arizona, ...
Cached Medicine Technology:Sequella Receives American Recovery and Reinvestment Funding Through the NIH 2Oral Cancer Foundation to Donate Screening Devices to Free Clinics 2Oral Cancer Foundation to Donate Screening Devices to Free Clinics 3Oral Cancer Foundation to Donate Screening Devices to Free Clinics 4
... The Accu-Chek InstantPlus Meter is ... that can perform cholesterol and ... This simple, CLIA-waived test provides ... 180 seconds. So you can ...
The Strep A Rapid Test Strip is a rapid chromatographic,immunoassay for the qualitative detection of Strep A antigen,from throat swab specimens to aid in the diagnosis of Group A,Streptococcal ...
...
... offers unparalleld speed, providing accurate, reliable ... only 10 ul of blood. Fast ... comprehensive patient care by spending more ... S System is easy-to-use, accurate, convenient, ...
Medicine Products: