Navigation Links
Brain cells help neighboring nerves regenerate
Date:5/27/2008

Researchers have uncovered a completely unexpected way that the brain repairs nerve damage, wherein cells known as astrocytes deliver a protective protein to nearby neurons.

Astrocytes are a type of support cell in the brain that serve many functions; one of their roles is to chew up damaged nerves during brain injury and then form scar tissue in the damaged area.

Roger Chung and colleagues have now found that astrocytes have another trick up their sleeve. During injury, astrocytes overproduce a protein called metallothionein (MT) and secrete it to surrounding nerves; MT is a scavenging protein that grabs free radicals and metal ions and prevents them from damaging a cell, and thus is a potent protecting agent.

While the ability of astrocytes to produce MT has been known for decades, the general view was that the MT stayed within astrocytes to protect them while they help repair damaged areas. However, Chung and colleagues demonstrated that MT was present in the external fluid of damaged rat brain. Furthermore, with the aid of a fluorescent MT protein, they observed that MT made in astrocytes could be transported outside the cell and then subsequently taken up by nearby nerves, and that the level of MT uptake correlated with how well the nerves repaired damage.

While the exact physiological role that MT plays in promoting better repair remains to be identified, this unexpected role for this protein should open up new avenues in treating brain injuries in the future.


'/>"/>

Contact: Nick Zagorski
nzagorski@asbmb.org
301-634-7366
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Vision restoration therapy shown to improve brain activity in brain injured patients
3. Clinical depression linked to abnormal emotional brain circuits
4. Brain imaging reveals breakdown of normal emotional processing
5. Brain cells work differently than previously thought
6. Vaccine Stops Alzheimers Brain Tangles
7. Research may unlock mystery of autisms origin in the brain
8. Scientists Spot Brains Free Will Center
9. Free will takes flight: how our brains respond to an approaching menace
10. Alcoholics With Cirrhosis Have More Brain Damage
11. Brain Lesions Predict MS Progression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... Curly Hair ... hair salons. This highly anticipated partnership between Curly Hair Solutions™ and Trade Secrets ... Founder Jonathan Torch and the Curly Hair Solutions™ team could not be more ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... Sculpted Contours ... of Atlanta’s Women of Power and Influence by Modern Luxury’s The Atlantan Magazine. ... the business as well as Kathy King. Her idea and vision to bring ...
(Date:8/31/2015)... ... August 31, 2015 , ... When it comes to undergoing a hair transplant, most patients ... head. Adding more volume to the hair on top of the scalp, as well ... a good amount of donor hair on other areas of their head. , What about ...
(Date:8/31/2015)... , ... August 31, 2015 , ... ... weight management program that is unique to the Lake Orion area. This program ... Macomb County. , WEmovestrong’s weight management program will incorporate group fitness and ...
(Date:8/31/2015)... ... 31, 2015 , ... Coast Dental Vista is celebrating its recent ... to 3 p.m. near Albertsons in the Foothill Center, located at 1279 E. Vista ... and Dr. Jay Lopp. Call (760) 208-2518 for more details or stop by on ...
Breaking Medicine News(10 mins):Health News:Curly Hair Solutions™ Partners With Trade Secrets 2Health News:Sculpted Contours Owner Selected One of Atlanta's Women of Power and Influence by Modern Luxury's The Atlantan Magazine 2Health News:Sculpted Contours Owner Selected One of Atlanta's Women of Power and Influence by Modern Luxury's The Atlantan Magazine 3Health News:Body Hair Transplants to Help Achieve a Full Head of Hair 2Health News:Discover How to Replace Missing Teeth, Reduce Cavities, and Restore Oral Health During Coast Dental’s Open House in Vista, CA on Sept. 5, 2015 2Health News:Discover How to Replace Missing Teeth, Reduce Cavities, and Restore Oral Health During Coast Dental’s Open House in Vista, CA on Sept. 5, 2015 3
... ... of Africa.,A Virtual Soccer Ball Created by I Imagine Studio To Be Signed by Thousands, ... ... Rotary’s campaign to eradicate the disease, I Imagine Studio has created an interactive, strategic viral ...
... ... premium library of photographs documenting real people and their emotions. Created by assignment photographers ... ) is one of the first stock photo agencies devoted solely to portraiture of ... ...
... ... ... 20, 2010 -- IT-Lifeline, the Northwest’s foremost provider of disaster recovery and business continuity ... that they have entered into a joint marketing agreement to provide a suite of ...
... with erlotinib for people with non-small-cell form of disease ... people with non-small-cell lung cancer, treatment with the drug ... rates, a new study suggests. , Non-small-cell lung ... cases. About half the time, people have advanced disease ...
... THURSDAY, May 20 (HealthDay News) -- Walk a little, and your ... thank you. , That,s the message of a new study that ... of an extremely common condition known as metabolic syndrome, which can ... shows a connection between more walking and better health -- it ...
... ... be presented on June 21 in New York City , ... Provo, Utah (Vocus) May 20, 2010 -- Tahitian Noni ... , , , ,The American Business Awards is the nation’s premier business awards program. All ...
Cached Medicine News:Health News:Rotary International and I Imagine Studio Have Teamed up to Helps Kick Polio out of Africa 2Health News:Rotary International and I Imagine Studio Have Teamed up to Helps Kick Polio out of Africa 3Health News:Citizen Stock Launches Industry's First Rights Managed Database of Images Shot Exclusively Against White 2Health News:IT-Lifeline, Inc and OptiStor Technologies, Inc. Enter Joint Marketing Agreement 2Health News:IT-Lifeline, Inc and OptiStor Technologies, Inc. Enter Joint Marketing Agreement 3Health News:Post-Chemo Treatment May Boost Lung Cancer Survival 2Health News:More Steps a Day Lead to Better Health 2Health News:More Steps a Day Lead to Better Health 3Health News:Tahitian Noni International Named As Finalist In 2010 American Business Awards 2
(Date:8/31/2015)... 2015  Chiasma, Inc. (NASDAQ: CHMA ), ... for the orphan condition acromegaly, today reported financial ... 2015 and provided a corporate update. ... time for Chiasma, as we successfully completed our ... first New Drug Application (NDA) has been accepted ...
(Date:8/31/2015)... 2015 With increasing clinical applications, the ... rise in active partnerships. The primary reason for ... quantitate CD4 cell markers in human immunodeficiency virus ... New analysis from Frost ... Market ( http://www.frost.com/nf0e ), finds the market earned ...
(Date:8/31/2015)... Aug. 31, 2015  The departments of Drug and ... at Gaudenzia Concept 90 to raise awareness for International ... in Pennsylvania and help more ... on recovery through the Building Bridges to Recovery ... dying every day to a disease that is fully ...
Breaking Medicine Technology:Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 2Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 3Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 4Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 5Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 6Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 7Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 8Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 9Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 2Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 3Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 4Pennsylvania Departments of Drug & Alcohol Programs and Health Kick-off Second Annual Building Bridges to Recovery Initiative 2
... Identify Unique microRNA Signatures That Will ... Project Will Leverage Rosetta Genomics, Proprietary microRNA Extraction, and Quantification Technologies, ... and Experience ... Patients With High Risk, of Recurrence, who may Benefit From Adjuvant ...
... Accrual and Expansion Plans for SB-509-701 Phase 2 Clinical Trial for ... ... Neuropathy, SAN FRANCISCO, June 6 Sangamo BioSciences,Inc. (Nasdaq: SGMO ... trial (SB-509-701) in subjects with moderate to,severe diabetic neuropathy. Additionally, based upon ...
Cached Medicine Technology:Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer 2Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer 3Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer 4Rosetta Genomics and M. D. Anderson to Develop a MicroRNA-based Diagnostic Test to Identify Risk of Recurrence of Lung Cancer 5Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs 2Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs 3Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs 4Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs 5
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: