Navigation Links
Brain cell transplants win Fernström Prize
Date:9/12/2011

This year's Fernstrm Foundation Nordic Prize, with prize money of SEK 1 million, goes to Professor Anders Bjrklund from Lund University, Sweden. He is a neurology researcher focusing on neurodegenerative diseases, diseases in which the nerve cells die. Professor Bjrklund's research group is trying to develop customised stem cells to treat Parkinson's disease.

Shipowner Eric K. Fernstrm's foundation is based at the Faculty of Medicine at Lund University. The Foundation awards an annual Nordic prize of SEK 1 million and local prizes of SEK 100 000 each to promising young researchers at Sweden's six university medical faculties.

This year's prize recognises Anders Bjrklund's "development of innovative forms of treatment for Parkinson's disease". The work began in the 1970s, when his research group were pioneers in transplanting new nerve cells into the brain. At the time, most researchers did not consider this either possible or meaningful.

"The prevailing view was that the brain was a sort of switchboard, a closed control room that couldn't be changed. Now, on the other hand, we know that the brain is plastic it changes all the time depending on the individual's development and possible diseases", says Anders Bjrklund.

The transplantation of brain cells has grown into a major international research field. In Lund, a number of patients with Parkinson's disease have received nerve cell transplants. However, the results have been mixed: some patients have seen a marked improvement, while others have not been affected at all. The fetal brain cells used in these trials are difficult to obtain in sufficiently large numbers, and too varied in quality to form the basis for a more regular treatment.

Hope is therefore in stem cells which are customised to produce dopamine, the substance which Parkinson's patients lack. The vision is to halt the progression of the disease at an early stage through a one-off treatment with these stem cells.

"This requires a surgical operation on the brain, of course. However, such operations have already been performed on many thousands of Parkinson's patients, for whom medication has not worked and who instead have received 'deep brain stimulation' via an electrode. The stem cells could be injected in a similar way via thin cannulas to different parts of the brain", explains Anders Bjrklund.

First, however, suitable stem cells must be developed and tested. The large research network around Anders Bjrklund is actively involved in this work. The aim is both to develop cells which function as planned without the risk of side-effects and to work out which patients benefit from the treatment.

"We believe that only a subgroup of Parkinsonpatients can benefit from receiving new dopamine-producing cells. We need to understand what characterises this group so that we don't subject any patients to an unnecessary procedure", says Anders Bjrklund.

However, he has a strong belief in the method.

"If we can show that a transplant of healthy nerve cells can help a brain damaged by Parkinson's disease to heal itself, then that principle could also be used for other neurological diseases", he says.


'/>"/>

Contact: Professor Anders Bjrklund
Anders.Bjorklund@med.lu.se
46-703-146-761
Lund University
Source:Eurekalert

Related medicine news :

1. New X-Rays Offer Clues on Evolution of the Human Brain
2. Stroke prevention trial finds intensive medical treatment has better results than brain stenting
3. Bilingual Homes Help Babies Exercise Their Brain: Study
4. Control of fear in the brain decoded
5. Brain Scans Show Distinct Traits in Kids With Autism: Study
6. Old-Age Tremors May Be Caused by Brain Lesions
7. Alzheimers brains found to have lower levels of key protein
8. Alcohol dulls brain alarm that monitors mistakes, MU study finds
9. Use Caution in Ending Life Support for Brain-Injured, Experts Say
10. Learning information the hard way may be best boot camp for older brains
11. Brain tumors found to have a 2-tier system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... January 20, 2017 , ... Michael and Betsy Brauser ... Cancer Institute. For Betsy, the clinical trial has been life-saving as she has ... worsened. , Betsy Brauser was diagnosed with ovarian cancer in 2009. She underwent ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Mary Magdalene: Grace is ... life of the woman who witnessed Jesus Christ firsthand. “Mary Magdalene: Grace is Greater ... spent her career as an educator interacting with countless women who had little knowledge ...
(Date:1/20/2017)... ... ... a fine examination of how God handles sin, including how to let go of ... who, for over ten long years has been waiting to release this powerful insight about ... has been serving the Lord for over twenty years, and he has been preaching and ...
(Date:1/20/2017)... ... ... and enchanting tale that teaches children the true meaning of Christmas. “Journey to Christmas” is ... a devoted woman of faith. , “Becoming a parent changes you. In my case, ... for years, but actually doing it might have been a while in coming if it ...
(Date:1/20/2017)... ... , ... “God's Miracle Man: Against All Odds”: an inspiring affirmation of ... Keith C. A. Tucker, son of Minister Delores Pinnock and a Jamaican native who ... Hardy , “While sitting up in bed, I felt a pounding headache. It was ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... Report Details ... Alzheimer,s Disease Therapeutics and ... our new study reveals trends, R&D progress, and predicted ... the Alzheimer,s disease therapeutics and diagnostics market. Our new ... - How is the Alzheimer,s disease therapeutics and diagnostics ...
(Date:1/19/2017)... , January 19, 2017 Incretin Mimetics/GLP-1 ... and Others The global anti-obesity drugs market ... first half of the forecast period and CAGR of 38.7% in ... to grow at a CAGR of 32.8% from 2016 to 2027. ... in 2021, and $24,063 million in 2027. ...
(Date:1/19/2017)... -- James Gilbart , ... 2):3-8; http://www.touchoncology.com/articles/optimising-clinical-outcomes-gastrointestinal-cancers-through-inhibiting-angiogenesis-and ...      ... in a supplement to European Oncology & Haematology ... by James Gilbart and Axel ...
Breaking Medicine Technology: