Navigation Links
Brain cell regrowth linked to benefits of exercise, sexual behaviors and reproductive issues
Date:3/10/2011

Tampa, Fla. (Mar. 10, 2011) Two studies published by an interdisciplinary team of Hong Kong researchers in the current special issue of Cell Transplantation (20:1), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ , link the regrowth of key adult brain cells (neurogenesis) in two critical areas of the brain to both the benefits of exercise as a stress reducer and also to sexual behavior and reproductive issues. The two studies reviewing the causes and impacts of neurogenesis came out of a recent Pan Pacific Symposium on Stem Cell Research held in Taichung, Taiwan.

Until the 1960s, the idea that the adult brain could experience neural cell re-growth was not accepted; research over the next 30 years confirmed that adult brain cells could, and did, in fact, regenerate. Recent research has focused on the role of neurogenesis. Subsequent important findings promise to change not only therapeutic interventions, but our understanding of aging, sexual potency and psychiatric diseases as well.

"The discovery of neural stem cells in the adult brain was a spectacular event that revolutionized the traditional view that the central nervous system did not generate new neurons in adulthood," said corresponding author Dr. Kwok-Fai So of the University of Hong Kong in the People's Republic of China. "Our research is focused on questions about the function and physiological significance of neurogenesis and what factors promote or suppress neurogenesis."

Physical exercise may counteract stress by promoting neurogenesis

"The beneficial effects of running correlated with increased adult neurogenesis, which may provide a hint that newborn neurons could be involved in counteracting stress-related disorders," said Dr. So. "Research has shown that exercise can improve mood and cognition and has also demonstrated that a deficit in adult neurogenesis may result in depressive disorders. Our research is aimed at examining the relationship between exercise as a way of combating stress and the possibility that exercise may promote neurogenesis and that neurogenesis functions as the mechanism of benefit."

According to the researchers, one important adult brain area that is a 'neurogenic zone' is the hippocampus, an area involved in memory and emotional regulation. The role of new neurons in hippocampal functions "remains poorly defined," however, but they add that the effect of stress on the hippocampus is well known. Stress, especially depression and post-traumatic brain injury, have been shown to shrink the hippocampus. Recent research has shown that exercise has a link to enhancing hippocampal 'plasticity' and the regrowth of neurons neurogenesis.

"Recent findings suggest that hippocampal neurogenesis plays a role in the beneficial effects of exercise in countering stress," they concluded.

Citation: Yau, S-K.; Lau, B. W-M.; So, K-F. Adult Hippocampal Neurogenesis: A Possible Way How Physical Exercise Counteracts Stress. Cell Transplantation 20(1):99-111; 2011.

Adult neurogenesis, reproduction and sexual behavior According to the researchers, recent studies suggest adult neurogenesis in the brain's subventricular zone (SVZ), which lines the ventricles (cavities) of the brain that contain cerebrospinal fluid, plays a role in reproductive function and possibly in maternal behaviors, although the function of "SVZ neurogenesis is obscure." They suggest that emerging evidence points to reproductive action and sexual cues, such as pheromones (known to play an important role in reproductive function), may play a role in regulating neurogenesis in the olfactory system, where the sense of smell is located, and in the SVZ. The precise contribution of newborn neurons to sexual behavior is still "under debate," the researchers point out. They cite animal studies showing that neurogenesis plays a role in female mate selection and that suppressed neurogenesis has been associated with decreased sexual performance.

"The potential importance of neurogenesis in sexual behavior, sexual cues and reproductive function has provided new insights," said Dr. So. "These insights might provide a better understanding of sexual dysfunction, sexual disorders and normal sexual functioning."

"These reviews show that the process of neurogenesis has far-reaching implications, including a beneficial exercise-induced response to stress and some degree of involvement with sexual behavior and reproduction," said Prof. Shinn-Zong Lin, professor of neurosurgery at China University Medical Hospital, Taiwan and chair of the Pan Pacific Symposium on Stem Cell Research where this work was first presented. "The studies reinforce the importance of a naturally occurring process that, until recently, was believed to be impossible."

Citation: Lau, B. W-M.; Yau, S-Y.; So, K-F. Reproduction: A New Venue for Studying Function of Adult Neurogenesis? Cell Transplantation 20(1):21-35; 2011.


'/>"/>

Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Related medicine news :

1. Deep brain stimulation research expands at Barrow
2. As Peer Pressure Increases, So Does Brains Ability to Resist It
3. Researchers selectively control anxiety pathways in the brain
4. New study proves the brain has 3 layers of working memory
5. Cerebral spinal fluid guides stem cell development in the brain
6. Which side of the brain rotates a mental picture?
7. Vascular brain disorder misdiagnosed as multiple sclerosis
8. Abnormal neural activity recorded from the deep brain of Parkinsons disease and dystonia patients
9. Brain implant surgeries at UCSF dramatically improve symptoms of debilitating condition
10. As we sleep, speedy brain waves boost our ability to learn
11. Brains Learning Ability Seems to Recharge During Light Slumber
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
Breaking Medicine Technology: