Navigation Links
Brain cell regrowth linked to benefits of exercise, sexual behaviors and reproductive issues
Date:3/10/2011

Tampa, Fla. (Mar. 10, 2011) Two studies published by an interdisciplinary team of Hong Kong researchers in the current special issue of Cell Transplantation (20:1), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ , link the regrowth of key adult brain cells (neurogenesis) in two critical areas of the brain to both the benefits of exercise as a stress reducer and also to sexual behavior and reproductive issues. The two studies reviewing the causes and impacts of neurogenesis came out of a recent Pan Pacific Symposium on Stem Cell Research held in Taichung, Taiwan.

Until the 1960s, the idea that the adult brain could experience neural cell re-growth was not accepted; research over the next 30 years confirmed that adult brain cells could, and did, in fact, regenerate. Recent research has focused on the role of neurogenesis. Subsequent important findings promise to change not only therapeutic interventions, but our understanding of aging, sexual potency and psychiatric diseases as well.

"The discovery of neural stem cells in the adult brain was a spectacular event that revolutionized the traditional view that the central nervous system did not generate new neurons in adulthood," said corresponding author Dr. Kwok-Fai So of the University of Hong Kong in the People's Republic of China. "Our research is focused on questions about the function and physiological significance of neurogenesis and what factors promote or suppress neurogenesis."

Physical exercise may counteract stress by promoting neurogenesis

"The beneficial effects of running correlated with increased adult neurogenesis, which may provide a hint that newborn neurons could be involved in counteracting stress-related disorders," said Dr. So. "Research has shown that exercise can improve mood and cognition and has also demonstrated that a deficit in adult neurogenesis may result in depressive disorders. Our research is aimed at examining the relationship between exercise as a way of combating stress and the possibility that exercise may promote neurogenesis and that neurogenesis functions as the mechanism of benefit."

According to the researchers, one important adult brain area that is a 'neurogenic zone' is the hippocampus, an area involved in memory and emotional regulation. The role of new neurons in hippocampal functions "remains poorly defined," however, but they add that the effect of stress on the hippocampus is well known. Stress, especially depression and post-traumatic brain injury, have been shown to shrink the hippocampus. Recent research has shown that exercise has a link to enhancing hippocampal 'plasticity' and the regrowth of neurons neurogenesis.

"Recent findings suggest that hippocampal neurogenesis plays a role in the beneficial effects of exercise in countering stress," they concluded.

Citation: Yau, S-K.; Lau, B. W-M.; So, K-F. Adult Hippocampal Neurogenesis: A Possible Way How Physical Exercise Counteracts Stress. Cell Transplantation 20(1):99-111; 2011.

Adult neurogenesis, reproduction and sexual behavior According to the researchers, recent studies suggest adult neurogenesis in the brain's subventricular zone (SVZ), which lines the ventricles (cavities) of the brain that contain cerebrospinal fluid, plays a role in reproductive function and possibly in maternal behaviors, although the function of "SVZ neurogenesis is obscure." They suggest that emerging evidence points to reproductive action and sexual cues, such as pheromones (known to play an important role in reproductive function), may play a role in regulating neurogenesis in the olfactory system, where the sense of smell is located, and in the SVZ. The precise contribution of newborn neurons to sexual behavior is still "under debate," the researchers point out. They cite animal studies showing that neurogenesis plays a role in female mate selection and that suppressed neurogenesis has been associated with decreased sexual performance.

"The potential importance of neurogenesis in sexual behavior, sexual cues and reproductive function has provided new insights," said Dr. So. "These insights might provide a better understanding of sexual dysfunction, sexual disorders and normal sexual functioning."

"These reviews show that the process of neurogenesis has far-reaching implications, including a beneficial exercise-induced response to stress and some degree of involvement with sexual behavior and reproduction," said Prof. Shinn-Zong Lin, professor of neurosurgery at China University Medical Hospital, Taiwan and chair of the Pan Pacific Symposium on Stem Cell Research where this work was first presented. "The studies reinforce the importance of a naturally occurring process that, until recently, was believed to be impossible."

Citation: Lau, B. W-M.; Yau, S-Y.; So, K-F. Reproduction: A New Venue for Studying Function of Adult Neurogenesis? Cell Transplantation 20(1):21-35; 2011.


'/>"/>

Contact: David Eve
celltransplantation@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Related medicine news :

1. Deep brain stimulation research expands at Barrow
2. As Peer Pressure Increases, So Does Brains Ability to Resist It
3. Researchers selectively control anxiety pathways in the brain
4. New study proves the brain has 3 layers of working memory
5. Cerebral spinal fluid guides stem cell development in the brain
6. Which side of the brain rotates a mental picture?
7. Vascular brain disorder misdiagnosed as multiple sclerosis
8. Abnormal neural activity recorded from the deep brain of Parkinsons disease and dystonia patients
9. Brain implant surgeries at UCSF dramatically improve symptoms of debilitating condition
10. As we sleep, speedy brain waves boost our ability to learn
11. Brains Learning Ability Seems to Recharge During Light Slumber
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... ... June 28, 2017 , ... American Farmer proudly announces the participation of ... winning television series, scheduled to broadcast fourth quarter 2017. American Farmer airs Tuesdays at ... supplier of garden pea seed. As demand grew, the small company located in Moscow, ...
(Date:6/28/2017)... Gainesville, VA (PRWEB) , ... June 28, 2017 ... ... asset protection assistance and financial consultations to communities in northern Virginia and DC, ... Center to help provide for patients with Alzheimer’s and other disorders that lead ...
(Date:6/27/2017)... Zurich, Switzerland (PRWEB) , ... June 27, 2017 , ... ... crowd to manage token assets on the Ethereum blockchain, has released their technical ... but until now, there has been little systematic approach for determining which offerings will ...
(Date:6/27/2017)... ... June 27, 2017 , ... A January 18th ... to reach a staggering $6.81 billion by the year 2024 according to a new ... faster rate than those made from titanium. Los Angeles area clinic Beverly Hills Periodontics ...
(Date:6/27/2017)... ... June 27, 2017 , ... ... Foundation Fundraiser hygiene symposium in Mystic, CT. Covering the process and maintenance strategies ... experience in these popular periodontal procedures. Drs. Toback and Urbanski practice as experienced ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... Datascope Corp. is voluntarily performing a worldwide field correction of certain ... failure code.     ... PART NUMBER ... 0998-UC-0446HXX; 0998-UC-0479HXX 0998-00-3013-XX;  0998-UC-3013-XX ... This field correction also applies to any ...
(Date:6/14/2017)...  ivWatch LLC, a medical device company focused on ... is pleased to announce it was the Bronze Winner ... and Equipment at the 2017 Medical Design Excellence Awards ... The award was presented by Medical Device and Diagnostics ... New York during MD&M East, ...
(Date:6/14/2017)... N.C. , June 14, 2017  In 2016, ... Creative Startups pitch competition and came away ... reality platform is described by Forbes as "entering the ... American Medical Association as teaching "empathy to medical professionals ... the startup was recently named a finalist for the ...
Breaking Medicine Technology: