Navigation Links
Brain Science Institute announces license agreement to develop treatments for neurological disease
Date:3/12/2010

Johns Hopkins University's newly formed Brain Science Institute's NeuroTranslational Program has entered into a licensing agreement with pharmaceutical company Eisai Inc. to discover and develop small molecule glutamate carboxypeptidase II (GCPII) inhibitors.

The NeuroTranslational Program was launched in 2009 staffed with seasoned drug-discovery scientists to work side by side with Johns Hopkins faculty to help translate basic science discoveries into small molecule therapeutics.

Under the terms of the agreement, Eisai has granted the Brain Science Institute, or BSI, non-exclusive U.S. rights to use its GCPII technology to generate inhibitor molecules for diseases of the central and peripheral nervous system, including peripheral neuropathy and neurodegeneration, Alzheimer's disease, stroke, and ALS, as well as non-central nervous system diseases.

BSI will be responsible for the GCPII research, drug discovery and preclinical activities. Eisai will have an exclusive option to develop and commercialize any drug molecules generated from the collaboration, which will be led by a joint steering committee of representatives from both entities. Barbara Slusher, Ph.D., chief scientific officer of the BSI's NeuroTranslational Program, will serve as the academic lead of the steering committee, along with the NeuroTranslational Program's Director of Medicinal Chemistry Takashi Tsukamoto, Ph.D.

"We believe this collaboration will strengthen our ability to bring a novel class of compounds to patients," said Slusher.

"It is a great accomplishment for this team to announce a licensing agreement of this kind within its first year of operation," said Jeffery Rothstein, M.D., professor of neurology and co-director of the program.


'/>"/>

Contact: Gary Stephenson
gstephenson@jhmi.edu
410-955-5384
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1

Related medicine news :

1. American Brain Tumor Association Recognizes Philadelphia Family Foundation With Annual Award
2. OASIS Recognized for Brain Fitness Programming
3. Carnegie Mellon research provides insight into brains decision-making process
4. Researchers discover brain tumors grow-or-go switch
5. U discovery gives insight into brain replay process
6. UW Symposium: How Disease, Therapy, Drugs and Meditation Reshape the Brain
7. iPhone Memory Aid for Scatterbrains, Aging Baby Boomers and Busy, Forgetful People
8. After a fight with a partner, brain activity predicts emotional resiliency
9. Free Brain IQ Quiz, Activities for Home “Brain-Boosting” and Seminar Offered from LearningRX Denver during National Brain Awareness Month
10. Ritalin Boosts Learning by Increasing Brain Plasticity, According to UCSF Research
11. Golf Fore Brain Cancer Research at the Barry Spiegelman Memorial Golf Classic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... Alcovit, a ... to ramp up its marketing efforts with its product now available through Jet.com. ... to the public. The effervescent powdered drink is designed to quickly detox the body ...
(Date:8/18/2017)... ... ... “Our Mountains to Climb: A Journey of Love and Faith Through Trials”: ... faith they shared to overcome struggles in life. “Our Mountains to Climb: A Journey ... Corcoran, a retired teacher and happily married since 1999; the author’s personal experiences drive ...
(Date:8/18/2017)... ... ... “Beyond Our Imaginations: The Infinite God”: shows the importance of God in living ... of published author, Mark Lawrence, born in Michigan, the author has lived in various ... greater man of God is that I have to be more mindful of feminine ...
(Date:8/18/2017)... ... ... Mandate for Kingdom Builders”: a call to walk as citizens of the Kingdom and ... published author, John F. McGeorge, Jr. Dr. John F. McGeorge Jr., B.A., J.D., ... three decades training pastors and Christian leaders. He also met his wife, Valerija, ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... , Aug. 7, 2017  Endo International plc ... reached agreements to resolve virtually all known U.S. mesh ... discussions to resolve the known remaining U.S. claims at ... payments beginning in the fourth quarter of 2017 and ... of its second quarter 2017 results, the Company intends ...
(Date:8/4/2017)... Aug. 3, 2017  Agragen, LLC, a ... in the biopharmaceutical, nutraceutical, and aquacultural feed sectors, ... its lead drug candidates, AGR131.  This drug is ... from the blood of patients suffering from inflammatory ... bowel disease. ...
(Date:8/2/2017)... Aug. 2, 2017 Fenita J. ... as a Pinnacle Lifetime Professional in the Field ... Manager at Turing Pharmaceuticals, AG. Her skills and ... relationship building.                ... 25 years of experience as a highly successful ...
Breaking Medicine Technology: