Navigation Links
Brain Scans Reveal Secrets of 'Writer's Cramp'
Date:4/15/2009

Condition may arise from abnormalities in nerve fiber bundles, scientists say

WEDNESDAY, April 15 (HealthDay News) -- A team of French researchers has linked abnormalities in certain neural pathways of the brain to the debilitating muscle disorder known as "writer's cramp."

The finding could lead to a better understanding of the neurological basis for the resulting loss of muscle control and coordination that characterizes this difficult-to-diagnose disorder -- also known as "hand dystonia." The condition can render a patient unable to write or even maintain a functional grip when trying to perform a simple task.

"These results demonstrate the presence of abnormalities in [brain] fiber tracts," that are located in areas known to be involved with writer's cramp, said study author Dr. Stephane Lehericy, director of the Center for NeuroImaging Research at Pitie-Salpetriere Hospital in Paris.

Lehericy explained that although prior research had already linked writer's cramp to problematic alterations in the gray matter in certain brain regions, the current investigation identified problems with the white matter of certain nerve pathways in brain areas that are responsible for generating motor commands.

Such white matter, explained Lehericy, "contains fiber bundles that convey information from one brain region to another, as well as to the spinal cord."

Lehericy and his team reported the findings in the April issue of the Archives of Neurology.

To explore linkages between the disorder and the brain, the French team conducted high-tech diffusion-tenor magnetic resonance imaging (DTI) to scan for brain abnormalities among 26 right-handed writer's cramp patients and 26 right-handed healthy participants.

Among the writers cramp patients, the scans uncovered structural abnormalities in the white matter from the primary sensorimotor cortex region of the brain to below-cortex regions such as the thalamus. The observed abnormalities were not present among the healthy participants.

Such connections, the researchers noted, are typically key to the proper transference of motor coordination instructions from the brain to the spine, brain guidance that ultimately enables proper limb movement.

Dr. Daniel Labovitz, director of the division of cerebral vascular disease at New York University's Langone Medical Center, said the French researchers used "a very interesting technique to look at a very interesting problem."

"This is a solid piece of work," he said, "and a fascinating area of research that touches on issues that go far beyond writer's cramp alone and has to do with a whole range of activity-related difficulties that clearly have to do with a problem with the brain."

"So this study builds on the little knowledge we have on an exceedingly rare and unusual issue for which we have virtually no treatment," Labovitz added. "No, this finding doesn't tell us what the brain changes mean exactly. But it does add incrementally and importantly to our understanding of the neurology underlying the problem."

More information

For more on writer's cramp, head to the Dystonia Medical Research Foundation.



SOURCES: Stephane Lehericy, M.D., Ph.D., director, Center for NeuroImaging Research, and professor, department of neuroradiology, Pitie-Salpetriere Hospital, Paris; Daniel Labovitz, M.D., director, division of cerebral vascular disease, New York University Langone Medical Center, and assistant professor, neurology, NYU School of Medicine, New York City; April 2009 Archives of Neurology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms
2. Gene Network Sciences Announces Brain Cancer Collaboration With M.D. Anderson
3. Reversing effects of altered enzyme may fight brain tumor growth
4. Aspirin Linked to Brain Microbleeds
5. Brain Balance(TM) Centers Picks Adam Kluger Public Relations (AKPR) to Help Promote New Book and Atlanta Event to Raise Awareness About Revolutionary New Way to Treat Learning Disorders; Atlantic Recording Artist/Country Music Star Zac Brown and Dr. Rober
6. Pathway to Wisdom May Be Found in Brain Circuitry
7. American Heart Association Statement Gives Guidance on Minimally Invasive Procedures to Treat Diseased Brain Vessels
8. Avastin effective at delaying brain tumor progression in recurrent disease
9. Elsevier and Brain Mapping Foundation co-host 6th Annual World Congress of IBMISPS
10. From Early Brain Development to Digestive Health, New Juicy Juice Beverages Aid Children Through Different Stages of Growth and Development
11. Computerized Brain Exercise Improves Memory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain Scans Reveal Secrets of 'Writer's  Cramp'
(Date:2/8/2016)... Park, KS (PRWEB) , ... February 08, 2016 , ... ... a leader in Mole removal products. , Moles are derived from a cluster of ... appear in all the wrong places and create a lifetime of embarrassment. Historically, ...
(Date:2/8/2016)... ... , ... Guruji Mahendra Kumar Trivedi is offering 3 days of accelerated personal ... birthday on February 10th. During this time, people can achieve better health, greater ... people from over 40 different countries as an “ordinary man with an extraordinary gift.” ...
(Date:2/8/2016)... ... ... According to research by the National Association of Dental ... certified or obtain continuing education. To increase patient awareness of the lack of ... to inform dentists and patients about the possible lack of skills and knowledge ...
(Date:2/7/2016)... (PRWEB) , ... February 07, 2016 , ... Women's Excellence ... National Wear Red Day. National Wear Red Day is the first Friday each ... Heart disease and stroke cause 1 in 3 deaths among women each year – ...
(Date:2/7/2016)... AZ (PRWEB) , ... February 07, 2016 , ... ... Neck and Facial Plastics, has added Kybella® to his medical and surgical expertise. ... a newly approved FDA injectable medication used as a non-surgical alternative for reduction ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... India , February 8, 2016 ... a new market research report "Ablation Technologies Market by ... (Csardiovascular, Cancer, Pain Management, Cosmetic Surgery, Ophthalmology, Gynecology) - ... studies the global market over the forecast period of ... $4.44 Billion by 2020, at CAGR of 10.5% from ...
(Date:2/8/2016)... Kan. , Feb. 8, 2016 /PRNewswire/ ... organization that formerly specialized in the development ... recently announced that it has divided its ... Capital. While Nueterra Capital will continue the ... services, NueHealth will operate a national system ...
(Date:2/8/2016)... , Feb. 8, 2016  A research team ... scientists has discovered details of how the abnormal breakage ... a particularly aggressive form of acute lymphoblastic leukemia (ALL). ... which genetic mutations trigger overproduction of immature cells, called ... The discoveries of the malfunction underlying the type called ...
Breaking Medicine Technology: