Navigation Links
Brain Scan Might Someday Spot Autism
Date:12/2/2010

By Jenifer Goodwin
HealthDay Reporter

THURSDAY, Dec. 2 (HealthDay News) -- A type of brain imaging that measures the circuitry of brain connections may someday be used to diagnose autism, new research suggests.

Researchers at McLean Hospital in Boston and the University of Utah used MRIs to analyze the microscopic fiber structures that make up the brain circuitry in 30 males aged 8 to 26 with high-functioning autism and 30 males without autism.

Males with autism showed differences in the white matter circuitry in two regions of the brain's temporal lobe: the superior temporal gyrus and the temporal stem. Those areas are involved with language, emotion and social skills, according to the researchers.

Based on the deviations in brain circuitry, researchers could distinguish with 94 percent accuracy those who had autism and those who didn't.

Currently, there is no biological test for autism. Instead, diagnosis is done through a lengthy examination involving questions about the child's behavior, language and social functioning.

The MRI test could change that, though the study authors cautioned that the results are preliminary and need to be confirmed with larger numbers of patients.

"Our study pinpoints disruptions in the circuitry in a brain region that has been known for a long time to be responsible for language, social and emotional functioning, which are the major deficits in autism," said lead author Nicholas Lange, director of the Neurostatistics Laboratory at McLean Hospital and an associate professor of psychiatry at Harvard Medical School. "If we can get to the physical basis of the potential sources of those deficits, we can better understand how exactly it's happening and what we can do to develop more effective treatments."

The study is published in the Dec. 2 online edition of Autism Research.

Dr. Stewart Mostofsky, medical director at the Kennedy Krieger Institute's Center for Autism and Related Disorders, called the study "intriguing." However, it remains to be seen if the test is sensitive enough to distinguish between autism and other developmental conditions that impact the brain.

"This is a very preliminary step and one that will require larger samples of children and a broader range of children with autism and other development disorders, particularly other developmental language disorders," Mostofsky said.

Also unknown is how old a child has to be for the deviations in brain circuitry to show up on the MRI. At birth, the brain's gray and white matter is largely undifferentiated, although this changes rapidly during the first 18 to 24 months, Lange said.

The specific type of MRI used is called diffusion tensor imaging, which offers information about the structure of the brain as opposed to how the brain "lights up" during particular activities.

Among the specific findings in participants with autism, the fibers in the right side of the superior temporal gyrus were more organized than the fibers on the left; the opposite was true in typical people.

"The left is language. Typical brains have nice, coherent, organized fiber structures," Lange said. "In those with autism, the left is less organized."

Researchers repeated the MRI test with a second set of participants and had similar success in predicting who had autism and who didn't.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more on autism.

SOURCES: Nicholas Lange, Sc.D., associate professor, psychiatry, Harvard Medical School, and director, Neurostatistics Laboratory, McLean Hospital, Boston; Stewart Mostofsky, M.D., medical director, Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore; Dec. 2, 2010, Autism Research, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gadgets not related to teenagers brain pain
2. Dementia Rates Escalate as Brain Capacity Diminishes with Age
3. Researchers discover new way to kill pediatric brain tumors
4. Scientists Pinpoint Area of Brain That Fears Losing Money
5. Physical Changes in Brain Linked to Altered Spirituality
6. Pro Athletes Brains React at Olympic Speed
7. Neuroscientists reveal new links that regulate brain electrical activity
8. Brain Scan Shows What Beauty is Worth
9. Study supports alternative anti-seizure medication following acute brain injury
10. Exercise helps protect brain of multiple sclerosis patients
11. Pittsburgh Neurosurgeons Explore Use of Drug that Illuminates Brain Tumor Cells To Guide Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain Scan Might Someday Spot Autism
(Date:6/25/2016)... ... ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize each ... Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into hand ... select a ProHand generator and drag it above media or text in the Final ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at www.diabetesscholars.org by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
Breaking Medicine Technology: