Navigation Links
Brain Protein May Have Potential Against Alzheimer's
Date:2/8/2009

Study in animals finds memory improvements and less cell degeneration

SUNDAY, Feb. 8 (HealthDay News) -- A naturally occurring brain protein appears able to slow or stop Alzheimer's disease in recent studies done on animal models.

The brain's entorhinal cortex, which supports memory, normally produces brain-derived neurotrophic factor (BDNF); however, its production appears to decrease when Alzheimer's is present. When researchers injected BDNF in lab animals that either were aged, had entorhinal cortex damage or were genetically altered to have Alzheimer's-like symptoms, they found that the animals had improved memory and cognitive skills and that cell degeneration and death was prevented or reversed.

"The effects of BDNF were potent," researcher Dr. Mark Tuszynski, professor of neurosciences at the University of California, San Diego, School of Medicine, said in a news release issued by the school. "When we administered BDNF to memory circuits in the brain, we directly stimulated their activity and prevented cell death from the underlying disease."

The animals receiving the treatment -- transgenic mouse models of Alzheimer's disease, aged rats, rats with induced damage to the entorhinal cortex, aged rhesus monkeys and monkeys with entorhinal cortex damage -- also showed long-term benefits. They began producing more BDNF on their own and exhibited better brain cell signaling and neuronal function, whereas the untreated animals degenerated further. The hippocampus, the brain's short-term memory processing center, which Alzheimer's disease can quickly damage, also appeared to show improvement.

The team, whose findings were published in the Feb. 8 issue of Nature Medicine, concluded that, since BDNF appeared both safe and effective on animal models, it could hold hope for treating Alzheimer's disease in humans.

"In this series of studies, we have shown that BDNF targets the corti
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. GEN Reports on Strategies to Overcome Blood-Brain Barrier
2. Medical research community needs to speak louder to prevent another Canadian brain drain
3. Heavy marijuana use may damage developing brain in teens, young adults
4. New insights into growth factors role in brain development
5. Aggressive Treatment Effective in Kids Brain Cancer
6. Mesh-like network of arteries adjusts to restore blood flow to stroke-injured brain
7. Study of Iraq veterans traumatic brain injuries to be conducted by UB researchers
8. Support cells, not neurons, lull the brain to sleep
9. Blast overpressure is generated from the firing of weapons and may cause brain injury
10. Physical therapists test mechanical arm to help patients recover from stroke, traumatic brain injury
11. Cutting Calories May Boost Aging Brains
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain Protein May Have Potential Against Alzheimer's
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining the main ... , Auto insurance quotes help many drivers find the ... to call an agent or visit an agency for price ... website: http://autocarinsurancebest.com/ . , Every business who relies heavily ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Carinsurancesavings.biz has released ... accidental death and dismemberment insurance . , Purchasing an ... can be very advantageous. This type of rider provides benefits ... dismemberment can be considered a lesser form of life insurance. ...
(Date:1/22/2015)... A study recently published in ... Medicine & Science in Sports & Exercise shows ... reduce gastrointestinal (GI) problems associated with physical strain ... the double-blind, placebo-controlled study took 10 grams of ...
(Date:1/22/2015)... Recently, Weddingshe.com has added many trendy Champagne wedding ... annual revenues in the past three years. Today, the business ... , According to the sales manager of the company, this ... in 2015. This point can be reflected on the discounted ...
(Date:1/22/2015)... Colorado (PRWEB) January 22, 2015 Four years since ... Queen – which coincided with the marriage of Avasa & Matthew ... THE ROAD, which is scheduled for release through White Swan Records ... message that there is a sacred path available to all of ...
Breaking Medicine News(10 mins):Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... those who take up the habit , , FRIDAY, May 9 ... in their everyday conversations with peers helps reduce smoking rates, ... study included almost 11,000 students, ages 12 to 13, at ... the schools, certain students were selected to receive training about ...
... May 9 Alseres,Pharmaceuticals, Inc. (Nasdaq: ALSE ... call on Thursday, May 15th, 2008 at 9:00am ... 2008 and discuss other matters related to,the Company., ... access the conference call, please dial 877-795-3649 for ...
... 9 Xmark Opportunity Partners,LLC, the investment manager ... and Xmark JV Investment Partners, LLC, announced,today that ... press release,issued by Genaera Corporation (Nasdaq: GENR ... base compensation, cash incentives to executives, workforce,reduction and ...
... standardization, ... and reduces costs, IRVINE, Calif., May 9 ... of Pulse CO-Oximetry and,Measure-Through-Motion-and-Low-Perfusion Pulse Oximetry, have announced ... Masimo SET pulse oximetry. The New Jersey-based hospital ...
... groups to reach,stricken Myanmar, EVANSTON, Ill., May ... to cyclone ravaged Myanmar, among the first,charities actually ... grassroots,disaster relief organization supported by Rotary clubs around ... volunteers was on the ground Thursday (May,8) preparing ...
... fruits and vegetables reduced brain plaques in mouse experiments ... found in many fruits and vegetables, may be able ... study suggests. , In experiments with mice, two flavonoids ... forms the harmful plaques that build up in the ...
Cached Medicine News:Health News:Training Student Leaders Cuts Peers' Smoking Rates 2Health News:Alseres Pharmaceuticals to Host 2008 First Quarter Conference Call 2Health News:Alseres Pharmaceuticals to Host 2008 First Quarter Conference Call 3Health News:Saint Barnabas Medical Center Converts to Masimo SET Technology - Establishing a Foundation for the Future of Pulse Oximetry 2Health News:Saint Barnabas Medical Center Converts to Masimo SET Technology - Establishing a Foundation for the Future of Pulse Oximetry 3Health News:Saint Barnabas Medical Center Converts to Masimo SET Technology - Establishing a Foundation for the Future of Pulse Oximetry 4Health News:Saint Barnabas Medical Center Converts to Masimo SET Technology - Establishing a Foundation for the Future of Pulse Oximetry 5Health News:Rotary Clubs Provide Emergency Shelters, Supplies to Cyclone Victims 2Health News:Flavonoids May Help Treat Alzheimer's 2Health News:Flavonoids May Help Treat Alzheimer's 3
(Date:1/23/2015)...  The Partnership to Fight Chronic Disease (PFCD) released a public opinion ... a new study analyzing the impact of increased cost sharing on ... working to educate policy makers and the public on the costs ... on how the Iowa healthcare exchange could ...
(Date:1/23/2015)... ATLANTA , Jan. 23, 2015 More than a ... a quarter of those with private insurance, filled a prescription ... to a report in this week,s Morbidity and Mortality Weekly ... health care providers to treat moderate to severe pain.  They ...
(Date:1/23/2015)... Inc., a leader in hand hygiene monitoring, today announced ... subsidiary of Ascendis Health Limited, in Johannesburg, ... of millions of patients around the world are affected ... patient to patient via the unwashed hands of healthcare ...
Breaking Medicine Technology:New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3HyGreen Partners with RCA Medical in Johannesburg, South Africa 2
... following letter is being released by CEL-SCI Corporation (NYSE Alternext ... Fellow Shareholders: , I am writing today to provide you ... you on our plans for dealing with the current financial ... a year of meaningful accomplishments which put CEL-SCI in a ...
... Pharmacyclics (Nasdaq: PCYC ) announced today the ... by the principals of Pacific Biopharma Group, Ltd. (PBG), ... People,s Republic of China. The transaction was structured as ... at $0.93/share. Robert Duggan, CEO of Pharmacyclics noted, ...
Cached Medicine Technology:CEL-SCI Corporation Releases Letter to Shareholders 2CEL-SCI Corporation Releases Letter to Shareholders 3CEL-SCI Corporation Releases Letter to Shareholders 4CEL-SCI Corporation Releases Letter to Shareholders 5Pharmacyclics, Inc. Announces Closing of a Private Financing With the Principals of Pacific Biopharma Group, Ltd. 2Pharmacyclics, Inc. Announces Closing of a Private Financing With the Principals of Pacific Biopharma Group, Ltd. 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: