Navigation Links
Brain Mechanism Can Turn Off Trauma of Bad Memories
Date:7/30/2008

Molecules that eliminate fear factor could lead to new panic disorder drugs

WEDNESDAY, July 30 (HealthDay News -- The brain mechanism that turns off traumatic feelings associated with bad memories has been identified by researchers at the University of California, Irvine, who said their finding may lead to the development of new drugs to treat panic disorders.

When a person suffers a traumatic experience, environmental cues often become associated with the bad experience. Subsequent exposure to the same cues can cause fear or even panic attacks, according to study author Rainer Reinscheid, an associate professor of pharmacology and pharmaceutical sciences.

The UCI team, along with colleagues from the University of Muenster in Germany, found that a protein called neuropeptide S (NPS) eliminates traumatic responses to bad memories by working on a group of neurons inside the amygdala, the brain region where negative memories are stored.

In experiments with mice exposed to situations that caused bad memories, the researchers found that blocking NPS receptors in the amygdala made traumatic responses to bad memories persist longer. But when the mice were treated with compounds that activated the NPS receptors, traumatic responses vanished sooner.

The findings are published in the July 31 issue of Neuron.

"The exciting part of this study is that we have discovered a completely new process that regulates the adverse responses to bad memories," Reinscheid said in a UCI news release. "These findings can help the development of new drugs to treat conditions in which people are haunted by persistent fears, such as post-traumatic stress disorder or other panic disorders."

Previous research has shown that erasing major negative experiences may require "new learning," such as exposure to the place where the bad experience occurred. This is the first study to identify specific neurons and molecules that eliminate fear memories from the brain.

More information

The U.S. National Institute of Mental Health has more about post-traumatic stress disorder.



-- Robert Preidt



SOURCE: University of California, Irvine, news release, July 30, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Vision restoration therapy shown to improve brain activity in brain injured patients
3. Clinical depression linked to abnormal emotional brain circuits
4. Brain imaging reveals breakdown of normal emotional processing
5. Brain cells work differently than previously thought
6. Vaccine Stops Alzheimers Brain Tangles
7. Research may unlock mystery of autisms origin in the brain
8. Scientists Spot Brains Free Will Center
9. Free will takes flight: how our brains respond to an approaching menace
10. Alcoholics With Cirrhosis Have More Brain Damage
11. Brain Lesions Predict MS Progression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... , ... December 08, 2016 ... ... Suite 10.2 version gives development continuity to its innovative Unified Instance Manager ... management capacity. In addition, this new version optimizes the unattended auto-dialing system ...
(Date:12/8/2016)... ... 08, 2016 , ... Today’s patients are encouraged to be ... SIGVARIS has created a new line of anti-embolism stockings to help prevent a ... benefits of graduated compression when transitioning from recovery to early rehabilitation. , The ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... planning services from offices headquartered in Jefferson County, is announcing the launch of ... in Birmingham. , The number of homeless women and children in Birmingham has ...
(Date:12/8/2016)... ... December 08, 2016 , ... Bill Mull ... business owners in and around central Kansas, is joining the Youth Horizons organization ... the region. , Headquartered in Wichita, Youth Horizons works to empower area children ...
(Date:12/7/2016)... NY (PRWEB) , ... December 07, 2016 , ... ... of the drug in their bodies, a researcher at the Icahn School of ... Pediatric Research. , The study found that when young children are exposed to ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... VIEW, Calif. , Dec. 8, 2016 IRIDEX ... intends to offer newly issued shares of common stock, $0.01 ... pursuant to an underwritten public offering.  The final terms of ... the time of pricing, and there can be no assurance ... IRIDEX expects to use the net proceeds it ...
(Date:12/8/2016)... Dec. 8, 2016 KEY FINDINGS ... Patient warming ... of blood during surgeries, lowering the risks of neurological disorders ... of SSIs. The patient warming systems can be segmented into ... benefits in turn reduce the stay at hospitals thus, lowering ...
(Date:12/8/2016)... KEY FINDINGS The global medical ... Various reasons for growth of the medical lifting sling ... chronic diseases, high recovery cost of injuries and government ... lifting sling refers to an assistive device that helps ... connect to the lift and hold the patient. It ...
Breaking Medicine Technology: