Navigation Links
Brain Glitch May Raise Some Girls' Odds of Depression
Date:4/5/2010

Study finds neural deficit in processing rewards and pleasure

MONDAY, April 5 (HealthDay News) -- Young girls at high risk for depression appear to have a malfunctioning reward system in their brains, a new study suggests.

The finding comes from research that included a high-risk group of 13 girls, aged 10 to 14, who were not depressed but had mothers who experienced recurrent depression and a low-risk group of 13 girls with no personal or family history of depression. Both groups were given MRI brain scans while completing a task that could result in either reward or punishment.

Compared with girls in the low-risk group, those in the high-risk group had weaker neural responses during both anticipation and receipt of the reward. Specifically, the high-risk girls showed no activation in an area of the brain called the dorsal anterior cingulate cortex, believed to play a role in reinforcing past experiences to assist learning.

The high-risk girls did have greater activation of this brain area when receiving punishment, compared with the other girls. The researchers said that this suggests that high-risk girls have an easier time processing information about loss and punishment than information about reward and pleasure.

"Considered together with reduced activation in the striatal areas commonly observed during reward, it seems that the reward-processing system is critically impaired in daughters who are at elevated risk for depression, although they have not yet experienced a depressive episode," wrote Ian H. Gotlib, of Stanford University, and his colleagues.

"Clearly, longitudinal studies are needed to determine whether the anomalous activations observed in this study during the processing of rewards and losses are associated with the subsequent onset of depression," they concluded.

The study was published in the April issue of the Archives of General Psychiatry.

More information

Mental Health America has more about teens and depression.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, April 5, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Hope for Brain, Spinal Cord Injuries
2. UPMC Health Plan Offers Brain Fitness Software to Improve Health
3. NFL Brain Injury Panel Raises Awareness of Potential Long-Term Consequences from Traumatic Brain Injuries
4. Melatonin precursor stimulates growth factor circuits in brain
5. Brain Scans Suggest Some Vegetative Patients May Be Aware
6. Brain Damage Seen in People With Severe Sleep Apnea
7. Alterations in the brains reward system related to attention-deficit/hyperactivity disorder
8. Brain dopamine receptor density correlates with social status
9. 3 brain diseases linked by toxic form of same neural protein
10. Brain Damage: NFL ‘Gets It,' American Society of Anesthesiologists Still Appears ‘Asleep'
11. Study finds reduced brain gray matter concentration in patients with severe obstructive sleep apnea
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join ... wage raise to $12 an hour by 2020 and then adjusting it yearly to increase ... of the minimum wage, assure the wage floor does not erode again, and make future ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners is ... sequencing and genomics experience, as Vice President of North American Capital Sales at ... for leading the sales team in the commercialization of the HTG EdgeSeq system and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
Breaking Medicine Technology: