Navigation Links
Brain Deficits Higher in Seniors Who Survive Blood Poisoning
Date:10/26/2010

TUESDAY, Oct. 26 (HealthDay News) -- Older adults who survive severe sepsis are at increased risk for new physical limitations and problems with mental functioning, a new study indicates.

This largely invisible problem swells the rolls of nursing homes and puts an increased burden on caregivers and families, as well as increasing the rate of depression and death among the elderly, the researchers said.

Also called "blood poisoning," sepsis is a potentially deadly infection in the blood or tissues that causes inflammation throughout the body. In cases of severe sepsis, the infection may lead to heart problems, organ failure or a sometimes fatal drop in blood pressure known as septic shock.

Researchers from the University of Michigan and colleagues analyzed data from 516 patients, average age 76.9, who survived severe sepsis and compared them to 4,517 patients who survived a hospitalization that wasn't due to the potentially life-threatening infection.

The study found that the prevalence of moderate to severe cognitive (brain) impairment was 10.6 percent higher among the severe sepsis survivors, and they had a 3.3 times greater risk of developing moderate to severe brain impairment than those hospitalized for reasons other than sepsis.

Severe sepsis survivors also had a higher rate of new limitations in physical functioning than those without hospitalized without sepsis, with an additional average increase of 1.5 things they could no longer do per patient among those who had no or mild to moderate functional limitations before they developed sepsis.

Their counterparts hospitalized for reasons other than sepsis had no change in cognitive function.

"Cognitive and functional declines of the magnitude seen after severe sepsis are associated with significant increases in caregiver time, nursing home admission, depression and mortality. These data argue that the burden of sepsis survivorship is a substantial, under-recognized public health problem, with major implications for patients, families and the health-care system," Dr. Theodore J. Iwashyna, of the University of Michigan Medical School, and colleagues, said in a news release.

They said hundreds of thousands of people develop severe sepsis each year in the United States, and nearly 20,000 new cases per year of moderate to severe cognitive impairment in elderly people may be due to sepsis.

"Thus, an episode of severe sepsis, even when survived, may represent a sentinel event in the lives of patients and their families, resulting in new and often persistent disability, in some cases even resembling dementia," the researchers wrote.

"Future research to identify mechanisms leading from sepsis to cognitive impairment and functional disability -- and interventions to prevent or slow these accelerated declines -- is especially important now given the aging of the population," they concluded.

The study appears in the Oct. 27 issue of the Journal of the American Medical Association.

More information

The Society of Critical Care Medicine has more about sepsis.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, Oct. 26, 2010.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Gadgets not related to teenagers brain pain
2. Dementia Rates Escalate as Brain Capacity Diminishes with Age
3. Researchers discover new way to kill pediatric brain tumors
4. Scientists Pinpoint Area of Brain That Fears Losing Money
5. Physical Changes in Brain Linked to Altered Spirituality
6. Pro Athletes Brains React at Olympic Speed
7. Neuroscientists reveal new links that regulate brain electrical activity
8. Brain Scan Shows What Beauty is Worth
9. Study supports alternative anti-seizure medication following acute brain injury
10. Exercise helps protect brain of multiple sclerosis patients
11. Pittsburgh Neurosurgeons Explore Use of Drug that Illuminates Brain Tumor Cells To Guide Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain Deficits Higher in Seniors Who Survive Blood Poisoning
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work ... as “patient engagement.” The patient is doing more than filling out a survey; in ... “There is an increasing emphasis in health care and research on the importance of ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... http://www.rebound-solution.com/ ...
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/19/2017)... ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device ... precise destruction of targeted tissues, announced three leadership team developments today:   ... Stopek, PhD ... ... Veteran medical device executive ...
Breaking Medicine Technology: