Navigation Links
Brain Activity Might Point to Early Alzheimer's
Date:9/25/2007

In future, quick diagnoses should mean better treatment, experts say

TUESDAY, Sept. 25 (HealthDay News) -- A specific pattern of brain activity could be a sign of early Alzheimer's disease, U.S. researchers report.

They noted that as new treatments for Alzheimer's become available, spotting the disease early will become critical.

A team at Duke University Medical Center in Durham, N.C., used functional magnetic resonance imaging (fMRI) to study the brains of 13 patients with mild Alzheimer's disease, 34 patients with mild cognitive impairment, and 28 healthy people (averaging about 73 years of age) as they did a memory task.

Participants with mild Alzheimer's and mild cognitive impairment showed impaired activity in the medial temporal lobe (MTL), an area of the brain associated with episodic memory that normally turns on during a memory task. Previous research had found that structural changes in the MTL are among the earliest known brain changes in people with Alzheimer's disease.

More surprisingly, the researchers found impaired deactivation in the posteromedial cortex (PMC), a brain area involved in personal memory that's usually suppressed during a memory task. The degree of PMC deactivation was closely related to the level of a patient's memory impairment and significantly correlated with their neuropsychological testing scores.

"In other words, the brain not only loses its ability to turn on in certain regions, but also loses its ability to turn off in other regions, and the latter may be a more sensitive marker. These findings give us insight into how the brain's memory networks break down, remodel and finally fail as memory impairment ensues," study lead author Dr. Jeffrey R. Petrella, an associate professor of radiology at Duke, said in a prepared statement.

He said the findings "implicate a potential functional, rather than structural, brain maker -- separate from atrophy -- that may help enhance diagnosis and treatment monitoring of Alzheimer's patients."

The study is published in the October issue of the journal Radiology.

More information

The Fisher Center for Alzheimer's Research Foundation has more about Alzheimer's diagnosis.



-- Robert Preidt



SOURCE: Radiological Society of North America, news release, Sept. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
4. “Brain fingerprinting”- The new lie detectr
5. Nasal Spray Could Take Drugs Direct to Brain.
6. Two doctors suspended for wrong brain surgery
7. The brain loves a surprise
8. Virus Combats Brain Tumour
9. Increase in sugar...decrease in brain function!!!
10. Alcohol shrinks brain
11. Roller coaster takes brain for a big ride!!
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/21/2017)... ... February 21, 2017 , ... Individuals who have been diagnosed ... surgery, treatment, therapy and management. Regular exercise in proper environments has been shown ... their diseases. On February 23, 2017, 1:00-2:00 p.m. E.S.T., a dynamic HydroWorx ...
(Date:2/21/2017)... NJ (PRWEB) , ... February 21, 2017 , ... ... research and conference coverage in veterinary medicine, will be launching its first bi-monthly ... animal health and medicine, business and practice management, and One Health. , ...
(Date:2/21/2017)... ... 2017 , ... Atlanta-based Jvion, the leading cognitive clinical science ... practice. Predixion, which raised $42M+ to date, received $20M in its third ... Ventures, and Software AG , will bring top industry talent and an impressive ...
(Date:2/21/2017)... ... February 21, 2017 , ... A February 6 article on Healio ... It found that the treatments have led to significant improvements in weight loss and ... efforts. It also noted very few problematic results relating to the treatment. Beverly Hills ...
(Date:2/20/2017)... Ill. (PRWEB) , ... February 20, 2017 , ... ... to reduce the rate at which women are called back for additional examinations ... journal Radiology . , In 2011, the U.S. Food and Drug Administration ...
Breaking Medicine News(10 mins):
(Date:2/21/2017)... MELBOURNE, Australia , Feb. 21, 2017  IBM (NYSE: ... IBM Watson,s ability to detect abnormalities of the eye,s retina. ... trained a research version of Watson to recognize abnormalities in ... insights and speed in their early identification of patients who ... glaucoma, a leading cause of blindness in the developed world. ...
(Date:2/21/2017)... Medical Oxygen Concentrators Market: Overview ... Medical oxygen concentrators are used by patients ... having low level of oxygen in their blood ... are to be used only with prescription and ... concentrators work either on rechargeable lithium batteries or ...
(Date:2/21/2017)...   BeyondSpring Pharmaceuticals , a clinical stage ... immuno-oncology cancer therapies, today announced that the Company,s ... 2 trial of BeyondSpring,s innovative lead asset, ... lung cancer (NSCLC) with Docetaxel has been selected ... Immuno-Oncology Symposium in Orlando, Fla. ...
Breaking Medicine Technology: