Navigation Links
Brain Activity Might Point to Early Alzheimer's
Date:9/25/2007

In future, quick diagnoses should mean better treatment, experts say

TUESDAY, Sept. 25 (HealthDay News) -- A specific pattern of brain activity could be a sign of early Alzheimer's disease, U.S. researchers report.

They noted that as new treatments for Alzheimer's become available, spotting the disease early will become critical.

A team at Duke University Medical Center in Durham, N.C., used functional magnetic resonance imaging (fMRI) to study the brains of 13 patients with mild Alzheimer's disease, 34 patients with mild cognitive impairment, and 28 healthy people (averaging about 73 years of age) as they did a memory task.

Participants with mild Alzheimer's and mild cognitive impairment showed impaired activity in the medial temporal lobe (MTL), an area of the brain associated with episodic memory that normally turns on during a memory task. Previous research had found that structural changes in the MTL are among the earliest known brain changes in people with Alzheimer's disease.

More surprisingly, the researchers found impaired deactivation in the posteromedial cortex (PMC), a brain area involved in personal memory that's usually suppressed during a memory task. The degree of PMC deactivation was closely related to the level of a patient's memory impairment and significantly correlated with their neuropsychological testing scores.

"In other words, the brain not only loses its ability to turn on in certain regions, but also loses its ability to turn off in other regions, and the latter may be a more sensitive marker. These findings give us insight into how the brain's memory networks break down, remodel and finally fail as memory impairment ensues," study lead author Dr. Jeffrey R. Petrella, an associate professor of radiology at Duke, said in a prepared statement.

He said the findings "implicate a potential functional, rather than structural, brain maker -- separate from atrophy -- that may help enhance diagnosis and treatment monitoring of Alzheimer's patients."

The study is published in the October issue of the journal Radiology.

More information

The Fisher Center for Alzheimer's Research Foundation has more about Alzheimer's diagnosis.



-- Robert Preidt



SOURCE: Radiological Society of North America, news release, Sept. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
4. “Brain fingerprinting”- The new lie detectr
5. Nasal Spray Could Take Drugs Direct to Brain.
6. Two doctors suspended for wrong brain surgery
7. The brain loves a surprise
8. Virus Combats Brain Tumour
9. Increase in sugar...decrease in brain function!!!
10. Alcohol shrinks brain
11. Roller coaster takes brain for a big ride!!
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... February 05, 2016 , ... The Muscular Dystrophy Association and ... launched the 14th annual “Appetite for a Cure” campaign on Feb. 1 to ... and related diseases that severely limit strength and mobility. , Now through ...
(Date:2/5/2016)... ... February 05, 2016 , ... After years as an active staff surgeon ... and cosmetic surgeon Dr. Wayne Carman transitioned to chief of the Division of Plastic ... first three-year term as chief and began a second three-year term in January of ...
(Date:2/5/2016)... ... , ... The American public tends to feel uncomfortable about drinking recycled waste ... or well water. The recent experience with lead contaminated water in Flint, Michigan, according ... toward increasing public acceptance of recycled waste water as drinking water. , The ...
(Date:2/5/2016)... ... February 05, 2016 , ... Pivot Point Consulting, a leading ... Software & Services for HIT Implementation Support & Staffing report with an outstanding ... performance by healthcare executives, managers and clinicians representing over 4,500 hospitals and 2,500 ...
(Date:2/5/2016)... ... February 05, 2016 , ... Dr. ... announces that it is now welcoming orthodontist, Dr. Amanda Cheng, to the practice. ... range of oral health care, including general dentistry, cosmetic treatments, periodontics, implant ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 Site Profile: --> ... - The Speech Recognition People, announced their latest primary healthcare case ... care, reduce turnaround times and to save the practice money. ... since 2013 Challenge: --> ,- Wirral CCG ... - Six doctors ,- Wirral CCG ,- VoicePower client since 2013 ...
(Date:2/4/2016)... WASHINGTON , Feb. 4, 2016  The ... Oversight and Government Reform Committee Chairman Jason ... (D-MD) for holding today,s hearing , "Developments ... drug price increases and growing questions about abusive ... Jason Chaffetz (R-UT) and Ranking Member Elijah ...
(Date:2/4/2016)... Feb. 4, 2016  Montoya Love is recognized by ... field of Pharmaceuticals. Montoya is the Regulatory Systems Operations ... Manufacturing and selling a ... Dickinson provides healthcare institutions, clinical laboratories and life ... countries across the globe. ...
Breaking Medicine Technology: