Navigation Links
Brain Activity Might Point to Early Alzheimer's
Date:9/25/2007

In future, quick diagnoses should mean better treatment, experts say

TUESDAY, Sept. 25 (HealthDay News) -- A specific pattern of brain activity could be a sign of early Alzheimer's disease, U.S. researchers report.

They noted that as new treatments for Alzheimer's become available, spotting the disease early will become critical.

A team at Duke University Medical Center in Durham, N.C., used functional magnetic resonance imaging (fMRI) to study the brains of 13 patients with mild Alzheimer's disease, 34 patients with mild cognitive impairment, and 28 healthy people (averaging about 73 years of age) as they did a memory task.

Participants with mild Alzheimer's and mild cognitive impairment showed impaired activity in the medial temporal lobe (MTL), an area of the brain associated with episodic memory that normally turns on during a memory task. Previous research had found that structural changes in the MTL are among the earliest known brain changes in people with Alzheimer's disease.

More surprisingly, the researchers found impaired deactivation in the posteromedial cortex (PMC), a brain area involved in personal memory that's usually suppressed during a memory task. The degree of PMC deactivation was closely related to the level of a patient's memory impairment and significantly correlated with their neuropsychological testing scores.

"In other words, the brain not only loses its ability to turn on in certain regions, but also loses its ability to turn off in other regions, and the latter may be a more sensitive marker. These findings give us insight into how the brain's memory networks break down, remodel and finally fail as memory impairment ensues," study lead author Dr. Jeffrey R. Petrella, an associate professor of radiology at Duke, said in a prepared statement.

He said the findings "implicate a potential functional, rather than structural, brain maker -- separate from atrophy -- that may help enhance diagnosis and treatment monitoring of Alzheimer's patients."

The study is published in the October issue of the journal Radiology.

More information

The Fisher Center for Alzheimer's Research Foundation has more about Alzheimer's diagnosis.



-- Robert Preidt



SOURCE: Radiological Society of North America, news release, Sept. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
4. “Brain fingerprinting”- The new lie detectr
5. Nasal Spray Could Take Drugs Direct to Brain.
6. Two doctors suspended for wrong brain surgery
7. The brain loves a surprise
8. Virus Combats Brain Tumour
9. Increase in sugar...decrease in brain function!!!
10. Alcohol shrinks brain
11. Roller coaster takes brain for a big ride!!
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... 20, 2017 , ... Chuck E. Cheese’s® and Center for Autism and Related ... Chuck E. Cheese’s locations throughout New England, New York and New Jersey to provide ... the fun of visiting Chuck E. Cheese’s in a sensory-friendly environment. , After ...
(Date:2/19/2017)... ... , ... Braun Industries will be participating as an exhibitor at EMS Today ... February 23-25, 2017 at the Calvin L. Rampton Salt Palace Convention Center in Salt ... ambulances on display. , “JEMS is a leader in EMS news and ...
(Date:2/18/2017)... , ... February 17, 2017 ... ... for Devicemakers , Sponsored by Axendia, **FDAnews Free Webinar**, March 1, 2017 ... manufacturers looking to reduce their regulatory burden? Pay dividends in enhanced and ...
(Date:2/18/2017)... , ... February 17, 2017 , ... Park Cities Pet ... Behave” Show on the Pet Life Radio network. The episode, which was posted ... of topics including: what factors led to Park Cities Pet Sitter’s being awarded the ...
(Date:2/17/2017)... TN (PRWEB) , ... February 17, 2017 , ... ... mobility has not kept pace. Enovate Medical has introduced an innovative workstation designed ... years of supporting nurses, the Encore Mobile EHR Workstation offers a lightweight, highly ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... N.Y. , Feb. 20, 2017  Henry ... of health care products and services to ... today announced that it has entered into ... Surgical (SAS), a leading U.S. distributor of ... dental anesthesiologists, and periodontists. SAS offers controlled ...
(Date:2/20/2017)... Wis. , Feb. 20, 2017  National ... MEDITECH to integrate the company,s CareSelect Imaging platform ... This formal agreement sets the technical foundation for ... access NDSC,s CareSelect Imaging Clinical Decision Support Mechanism ... to work directly with and support the integration ...
(Date:2/20/2017)... 2017 Seal Shield LLC ( Jacksonville, ... mobile device management and disinfection, the ElectroClave™, to the ... in Orlando, Fla. from February ... have become commonplace in today,s healthcare landscape, but with ... concerns, including the disinfection and tracking of these devices.  ...
Breaking Medicine Technology: