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Bradmer provides clinical trial update and announces evaluation of strategic alternatives
Date:2/17/2009

are evaluating strategic options related to the Bradmer assets and resources. While the cash on hand is not enough to finish the clinical trial, it is substantial enough to warrant careful consideration of proper deployment. It is envisioned that this strategic evaluation process will be reviewed by the Directors in March and recommendations will be forthcoming.

About Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is the most common and most advanced form of brain cancer with approximately 30,000 new cases diagnosed each year in the world's seven largest healthcare markets. Unlike many other solid tumors, GBM tumors do not metastasize, but cause symptoms and often death through invasion of nearby tissues and impairment of brain function. The current standard of care, consisting of surgery, radiation and adjuvant chemotherapy (temozolomide), extended average overall patient survival from 53 to 64 weeks.

About Neuradiab

Neuradiab is a monoclonal antibody, conjugated to radioactive iodine, used to treat glioblastoma multiforme (GBM), the most common and most advanced form of brain cancer. Neuradiab delivers tumor-killing radiation specifically to residual brain tumor cells after surgery, with minimal impact on normal brain tissue. During the course of development at Duke University, over US$60 million in research grants and related support has produced a series of Phase I and Phase II clinical trials on Neuradiab and other closely related technologies. Approximately 200 brain cancer patients, including over 160 with GBM, have been treated with the Neuradiab therapy regimen, and survival benefits have significantly exceeded historical controls in each completed trial. Neuradiab has been formerly referred to in literature as 131-I anti-tenascin monoclonal antibody 81c6.

GBM tumors typically have infiltrating edges that are very difficult to completely remove with surgery. The Ne
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SOURCE Bradmer Pharmaceuticals Inc.
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