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Bowel prep oral sodium phosphate equal to fasting before capsule endoscopy for obscure GI bleeding
Date:6/17/2008

OAK BROOK, Ill. JUNE 18, 2008 According to a new study from researchers in France, bowel preparation with oral sodium phosphate for capsule endoscopy in patients with obscure gastrointestinal (GI) bleeding is no better at cleansing the small bowel than the standard method of preparation, which is an eight-hour fast before the procedure. The study appears in the June issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

Capsule endoscopy (CE) is performed via a swallowed capsule containing a tiny video camera. The capsule, about the size of a large vitamin pill, contains a light source, batteries, a radio transmitter and an antenna. The capsule transmits the images to a recording device worn around the patient's waist. When complete, the recording is downloaded to a computer where the images are reviewed by the physician. The capsule is disposable and usually takes eight hours to move through the digestive system, after which it is passed harmlessly in a bowel movement. Capsule endoscopy does not require sedation and is painless. Capsule endoscopy can be used to diagnose hidden GI bleeding, Crohn's disease, celiac disease, and other malabsorption problems, tumors (benign and malignant), vascular malformations, medication injury, and to a lesser extent, esophageal disease. Currently, capsule endoscopy cannot be used to biopsy or treat any conditions.

Diagnostic results of CE may be reduced when visibility of the mucosa is impaired because of intestinal content or slow capsule progression. Prior to this study, there was only a limited consensus that preparations or prokinetics (drugs that promote gastrointestinal motility) probably improve the quality of small bowel cleanliness. Currently, an overnight fast only is proposed by the CE manufacturer.

"The aim of our study was to compare bowel preparation with oral sodium phosphate versus none
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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