Navigation Links
Bowel Disease Treatment May Raise Skin Cancer Risk
Date:10/26/2009

Rates of non-melanoma cancer higher in patients with Crohn's, ulcerative colitis, study finds

MONDAY, Oct. 26 (HealthDay News) -- Inflammatory bowel disease (IBD) patients who are being treated with immunosuppressive medications may be at increased risk for non-melanoma skin cancer, a new U.S. study says.

Researchers analyzed data on 26,403 Crohn's disease patients and 26,974 patients with ulcerative colitis in order to evaluate how the use of immunosuppressive and biologic medications to treat IBD affected non-melanoma skin cancer risk.

The study found that the incidence of non-melanoma skin cancer was higher in IBD patients than in a control group. Recent use (within 90 days) of any immunosuppressive medication was associated with greater risk of non-melanoma skin cancer (adjusted odds ratio 3.28), as was recent use of the thiopurine class of immunosuppressive medications (adjusted odds ratio 3.56) and recent use of biologic medications in Crohn's disease patients (adjusted odds ratio 2.07).

Persistent use of any immunosuppressive medication, which was considered use for over one year, was strongly associated with non-melanoma skin cancer (adjusted odds ratio 4.04), the study authors noted. The association was even stronger with persistent use of thiopurine medications (adjusted odds ratio 4.27). In Crohn's disease, persistent use of biologic medications was also associated with a raised risk (adjusted odds ratio 2.18).

"The increased risk of [non-melanoma skin cancer] in patients with IBD is likely related to the immunosuppressive medications used to treat the disease, although we can't rule out changes to the immune system itself as a result of IBD as contributing to this risk," said study leader Dr. Millie Long, of the University of North Carolina at Chapel Hill.

"In patients on immunosuppression therapy after organ transplant, previous studies have shown a clear association with [non-melan
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

0

GOOD

Page: 1 2

Related medicine news :

1. Elsevier announces new journal on inflammatory bowel diseases
2. C-diff infection 4 times more likely to kill patients with inflammatory bowel disease
3. Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients
4. Threshold for bowel surgery may be too high, warn experts
5. Antegrade bowel intussusception can cause recurrent, chronic postoperative intestinal obstruction
6. Bowel cancer screening halves emergency admissions and cuts deaths
7. Emmaus Medical, Inc. Enters Into Sub-License Agreement for Treatment of Short Bowel Syndrome
8. Interactive Teleconference on Inflammatory Bowel Disease for Patients, Caregivers, and Healthcare Professionals
9. Allergic disease linked to irritable bowel syndrome
10. Abuse history affects pain regulation in women with irritable bowel syndrome
11. Harnessing the Mind to Manage Irritable Bowel Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2009)... but not delivered ,, WASHINGTON, Dec. 15 ... to ensure that healthcare reform does not override ... insurance companies in 37 states. ,, Prostate cancer ... the population and individuals who are identifiable as ... who have a family history of prostate cancer. ...
(Date:12/15/2009)... 15 4R Systems, Inc., a leading ... which help retailers significantly increase profits by optimizing ... today that The Vitamin Shoppe has been utilizing ... store and DC inventory solutions have helped us ... in-stocks over the last two years," said Tony ...
(Date:12/15/2009)... following are the remarks by Lanny A. ... at the Medicare Fraud Strike Force press conference: ... for the enormous effort everyone at HHS is ... our Departments have and will continue to accomplish ... progress in fighting Medicare fraud in South Florida, ...
(Date:12/15/2009)... Lead to Indictment of 30 Individuals Charged in ... Million in Fraudulent Billing to Medicare ... have been charged in three cities for their ... $61 million in false Medicare claims as part ... Strike Force, Department of Health and Human Services ...
(Date:12/15/2009)... Volunteer service, such as tutoring children, can help ... according to a study led by researchers at ... Using functional magnetic resonance imaging (fMRI), the researchers ... program made gains in key brain regions that ... one,s daily life. The study is the first ...
Breaking Medicine News(10 mins):Health News:Men's Health Network Calls on Congress to Complete President Obama's Promise on Health Care Reform 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 2Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 3Health News:4R's Profit Optimizing Inventory Solutions Helps The Vitamin Shoppe Drive Increased Productivity and Performance 4Health News:Remarks by Lanny A. Breuer, Assistant Attorney General for the Criminal Division, at the Medicare Fraud Strike Force Press Conference 2Health News:Remarks by Lanny A. Breuer, Assistant Attorney General for the Criminal Division, at the Medicare Fraud Strike Force Press Conference 3Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 2Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 3Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 4Health News:Medicare Fraud Strike Force Expands Operations Into Brooklyn, N.Y.; Tampa, Fla.; and Baton Rouge, La. 5Health News:For older adults, participating in social service activities can improve brain functions 2
... Sunday, smoking ban in enclosed public places will be activated. ... studies// in the world that will probe the impact of ... ,The study, budgeted at a mammoth ?140,000, will be funded ... University researchers, who will study the health of 360 bar ...
... Dana-Faber Cancer Institute has come out with a new ... life-threatening complication of donor bone marrow and stem cell ... drug known as rituximab, grew out of recent discoveries ... transplanted cells and recipients' own tissue. In the new ...
... A case of hospital negligence stands substantiated in yesterday’s ruling ... to a lady patient who had suffered a large abscess. ... had she been referred to a specialist. The hospital had ... ,A fatal accident inquiry has revealed that due to ...
... (WHO) and UNICEF have announced a new formula for ... designed to minimize the occurrence of acute diarrhoeal disease.// ... achieve the target of reducing child mortality by two-thirds ... of child mortality and kills nearly 2 million children ...
... Ministry of Health in China has revealed that just over ... of HIV/AIDS//. ,This survey was conducted recently by a ... answers from 1,919 respondents in 24 colleges of 19 cities.,The ... are aware of how HIV/AIDS is transmitted and 75.6 per ...
... lower the risks of a heart attack, according to ... are laid down early in life. ,Helen ... Dallas, and her colleagues examined nearly 13,000 people enrolled ... Minnesota, North Carolina and Maryland, reported the online edition ...
Other Medicine News:Health News:Rituximad Can Treat Chronic Graft-Versus-Host Disease: Study 2Health News:Rituximad Can Treat Chronic Graft-Versus-Host Disease: Study 3
(Date:12/15/2009)... PARK, Calif., Dec. 15 SRI International, ... today the award of U.S. patent 7,592,021 for ... enhanced release of drugs through the human body,s ... drug delivery and allows for a much longer ... or liquids. ,, Transmucosal delivery is an effective ...
(Date:12/15/2009)... Medical researchers with EDP Biotech Corporation ... new technology for a simple blood test to ... the success of its pre-clinical trials for the ... the biomarker, CA11-19, and all aspects of its ... will detect colon cancer in its earliest, most ...
(Date:12/15/2009)... Cumberland Pharmaceuticals Inc. ( CPIX) ... a patient preference study evaluating Kristalose ( lactulose ... as a crystalline powder, compared to similar products ... prescription-strength laxative available in pre-measured powder packets. Over ... diagnosis of chronic constipation were administered both Kristalose ...
Breaking Medicine Technology:SRI International Receives U.S. Patent for Needle-Free Transmucosal Drug Delivery System 2SRI International Receives U.S. Patent for Needle-Free Transmucosal Drug Delivery System 3SRI International Receives U.S. Patent for Needle-Free Transmucosal Drug Delivery System 4SRI International Receives U.S. Patent for Needle-Free Transmucosal Drug Delivery System 5Researchers Announce Medical Breakthrough with Simple, Inexpensive Blood Test for Colon Cancer 2Kristalose(R) Preferred by Patients With Chronic Constipation Compared to Similar Products in a Recent Study 2Kristalose(R) Preferred by Patients With Chronic Constipation Compared to Similar Products in a Recent Study 3Topping Out Ceremony Marks Milestone in Construction of University Medical Center of Princeton at Plainsboro 62579 1Topping Out Ceremony Marks Milestone in Construction of University Medical Center of Princeton at Plainsboro 62579 2Topping Out Ceremony Marks Milestone in Construction of University Medical Center of Princeton at Plainsboro 62579 3Topping Out Ceremony Marks Milestone in Construction of University Medical Center of Princeton at Plainsboro 62579 4Ginger Prices Could Skyrocket on H1N1 Fears 62576 1Ginger Prices Could Skyrocket on H1N1 Fears 62576 2AAHSA Statement on Passage of Bennet Health Reform Amendment 62573 1
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: