Dr. Brent Moelleken, a plastic and reconstructive surgeon in Beverly Hills and Santa Barbara, Calif., noted that Reloxin has not yet been compared head-to-head with Botox.
"The safety profile appears similar to Botox, but perhaps more drooping than is usual with Botox," Moelleken said. "The big question about how Reloxin works, the volume of distribution, was not addressed, or technical differences, which may account for the greater drooping than most injectors see with Botox."
For his part, Salomon said he is "concerned with the increased incidence of ptosis [with Reloxin] and the lack of specificity of that ptosis -- brow versus lids. If it is all lid ptosis then I would consider it as an unintended spread of the material beyond the desired treatment area. That would not be a helpful or predictable component in the product's use," he said.
More information
For more information on Botox, visit the U.S. National Library of Medicine .
SOURCES: Ronald Moy, M.D., Moy-Fincher Medical Group, Los Angeles; Brent Moelleken, M.D., plastic and reconstructive surgeon, Beverly Hills and Santa Barbara, Calif.; Jeffrey C. Salomon, M.D., assistant clinical professor, plastic surgery, Yale University School of Medicine, New Haven, Conn.; Kamran Jafri, M.D., Jafri Craniofacial Plastic Surgery, New York City; March/April 2009 Archives of Facial Plastic Surgery
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