Navigation Links
Both real and 'sham' acupuncture help ease side effects of widely used breast cancer drug

BALTIMORE December 23, 2013. Breast cancer patients experience fewer side effects while being treated with a widely used drug called an aromatase inhibitor when they get acupuncture either the real treatment or a "sham" procedure, according to a new study led by researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center. Their findings are published online in Cancer, a peer-reviewed journal of the American Cancer Society.

"We found that patients with early stage, hormone receptor-positive breast cancer taking an aromatase inhibitor showed significant improvement in some symptoms, especially hot flashes, after eight weekly treatments with real acupuncture or sham acupuncture," says lead author Ting Bao, M.D., D.A.B.M.A, M.S., assistant professor of medicine at the University of Maryland School of Medicine and research scientist at the University of Maryland Greenebaum Cancer Center.

"There was no statistically significant difference between the two interventions," Dr. Bao says. She notes that the study sample of 47 women 23 who received real acupuncture and 24 who had the sham procedure may not have been large enough to detect a distinction. In addition, sham acupuncture, which is performed using non-penetrating, retractable needles at non-acupuncture points in the body, may have some unexplained physiological effects. "We are not convinced that sham acupuncture is totally inert," she says.

"Importantly, neither type of acupuncture produced any significant side effects, which is good news for patients," Dr. Bao says.

Up to 60 percent of postmenopausal women with breast cancer who take an aromatase inhibitor, which inhibits an enzyme involved in producing estrogen, experience joint and muscle pain and other side effects, such as hot flashes, anxiety and depression. The study findings may lend support to the use of acupuncture to treat these symptoms.

"If we really want to find something that will help patients, acupuncture is a reasonable alternative to drug therapy, which can produce its own set of side effects," Dr. Bao says. For example, antidepressants used to treat hot flashes can cause side effects such as nausea, constipation, dry mouth and drowsiness.

According to Dr. Bao, the research team did not set out to look at racial differences, but in analyzing the data, found that African-American patients benefited more than non-African-Americans from real acupuncture, compared to sham acupuncture, in reducing the severity and frequency of hot flashes. Researchers plan additional studies to investigate this finding.

The patients enrolled in the study were treated at the University of Maryland Greenebaum Cancer Center and the Johns Hopkins Kimmel Cancer Center. Vered Stearns, M.D., professor of oncology at the Johns Hopkins University School of Medicine and co-director of the breast cancer program at the Kimmel Cancer Center, is the study's senior author.

The research was supported by grants from the American Society of Clinical Oncology, Susan G. Komen for the Cure, the Breast Cancer Research Foundation, the Maryland affiliate of Susan G. Komen and the National Cancer Institute (K12 CA126849, R21 CA173263).

E. Albert Reece, M.D., Ph.D., M.B.A., vice president for medical affairs at the University of Maryland and the John Z. and Akiko K. Bowers Distinguished Professor and Dean of the University of Maryland School of Medicine, says, "Aromatase inhibitors are a very important advance in treating postmenopausal women with estrogen receptor-positive breast cancer, but side effects may cause some patients to stop treatment. This study led by Dr. Bao, an oncologist and medical acupuncturist, offers some intriguing evidence that acupuncture even sham acupuncture may be helpful in alleviating some side effects. These findings warrant further investigation."

In February 2013, Dr. Bao and her colleagues reported similar findings in the journal Breast Cancer Research and Treatment in regard to joint and muscle pain associated with treatment with aromatase inhibitors. They found that acupuncture and sham acupuncture improved breast cancer patients' symptoms but saw no statistical difference between the two interventions.


Contact: Karen Warmkessel
University of Maryland Medical Center

Related medicine news :

1. Nora Ross, Maker of Popular Unscented Garlic Shampoo, Announces November Sale
2. Corner Store Raises $2.3 Million for MDA Shamrocks Program
3. Give Hair a Lift with eShave’s New Triple Action Shampoo and Conditioner, Formulated to Eliminate Dandruff, Add Body, and Reduce Hair Loss
4. Outer Banks' Kitty Dunes Rentals: Gold Sponsors For The 6th Annual First Flight Cruisers Shamrock Car Show And Poker Run in Kill Devil Hills, NC
5. Shame about past alcoholism predicts relapse and declining health in recovering alcoholics
6. Shamanic Healer PaLiChi Restores Peace & Harmony to Struggling Catering Business with Alternative Healing Remedy and Blessings
7. Blue Deer Center Presents "Healing Camp: Five Days of Traditional Huichol Shamanic Healing" March 15-20, 2013
8. 4,000-year-old shamans stones discovered near Boquete, Panama
9. Places Clay Shampoo on Its Virtual Shelves
10. What is the central analgesic mechanism of acupuncture for migraine?
11. Getting the Point Acupuncture Bringing High Quality and Affordable Treatments
Post Your Comments:
(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... MIAMI , Sept. 27, 2017  Commended for their ... recent notable awards. Ranked as number one in the South ... ninth time in Inc. 5000 yearly list, the national specialty ... CEO, Armando Bardisa will soon be honored by ... Set to receive his award ...
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology: