Navigation Links
Boston University research suggests new pathways for cancer progression
Date:2/9/2012

BOSTON (2-8-12) Observing that certain cancer cells may exhibit greater flexibility than normal cells, some scientists believe that this capability promotes rapid tumor growth. Now computer simulations developed by Boston University Biomedical Engineering Assistant Professor Muhammad Zaman and collaborators at the University of Texas at Austin appear to support this view. A 3D model of healthy and cancer cells that they've created indicates that the softening of cancer cells not only accelerates their proliferation but also extends their lifetimea one-two punch that may trigger the rapid growth of malignant tumors.

The team's simulations and findings herald a new, quantitative approach to understanding tumor development centered on a small number of mechanical properties rather than multiple biochemical factors.

"Our study is unique in that it takes into account in vivo data on the mechanical properties of cancer cells," said Zaman. "Our novel computer simulation provides a platform to examine how stiffness of cancer cells influences their growth, and could lead to the development of early interventions."

Combining Zaman's expertise in cancer and cell migration with UT-Austin Chemical Engineering Professor Roger Bonnecaze's knowledge of fluid mechanics and postdoctoral fellow Parag Katira's computer simulation skills, the researchers produced a 3D computer model that systematically traces the impact of cell softness and other mechanical factors on cell behavior within a tissue. The model represents each cell as a liquid core encased by a spherical, viscous, elastic shell that can bind or stick to other cells to form a tissue-like mass. In simulations, individual cells are programmed to live, die or divide based on a set of rules drawn from real-time, in vivo experiments with tumor cells.

To emulate tumor growth, the researchers established a baseline simulation of tissue composed exclusively of hard-shelled, healt
'/>"/>

Contact: Mike Seele
mseele@bu.edu
617-353-9766
Boston University College of Engineering
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Boston University researcher awarded 2 NIH grants
2. Dana-Farber/Childrens Hospital Boston study identifies possible therapy for radiation sickness
3. Researchers from Boston University receive grant to develop improved virus detection system
4. Boston researchers share in $10 million grant to study HIV and alcohol
5. Institute for Aging Research study finds Bostons elderly homeless sicker than others
6. Boston Medical Center awarded $1M to expand HIV/AIDS patient care services
7. Boston University School of Medicine professor honored by the Endocrine Society
8. Boston Medical Center chief honored by AUA
9. Boston University researchers validate important roles of iPSCs in regenerative medicine
10. Boston University researchers find most substance-dependent individuals report poor oral health
11. Boston University School of Medicine professor receives award for quality of care research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Boston University research suggests new pathways for cancer progression
(Date:4/25/2015)... The URO CENTER of NEW YORK is ... by the New York Academy of Medicine to receive the ... field of Urology. , Dr. Ferdinand Valentine, born in 1851, ... He was a man of rare and attractive personality ... Not only did he devote his life to his profession ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Bird B Gone, ... residential applications now offers a complete line of bird control ... poultry farms. , New Flu Strains Threaten Pacific, Central and ... USDA post , a number of highly pathogenic avian ... The disease is often spread when wild birds enter poultry ...
(Date:4/24/2015)... Foothill Ranch, California (PRWEB) April 24, 2015 ... that has a wide range of capabilities and services ... etc. , Ryadon's Quantity Discount Program will be ... ) as follows: , Order 4-19: Receive 10% discount ... Can Benefit by Using the Drawer Slides Products, ...
(Date:4/24/2015)... The 1975 have had an ... the globe to theaters, festivals and TV performances. Now that ... with their label, Dirty Hit Records, to provide clean drinking ... newly launched Cadence & Cause website, this four-piece ... vinyl and a signed photo card. Entries from this ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post ... qualify for auto insurance as a single ... insurance online, without having to follow a special process. ... can reduce their auto insurance expenses. The tips are ... , Clients can now visit an insurance brokerage ...
Breaking Medicine News(10 mins):Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 2Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 3Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 2Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 3Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 4Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
... LAUDERDALE, Fla., Sept. 1 In November, the world,s most ... (NAC) in Florida to cover everything from cutting-edge research to ... , The speaker lineup is set to ... Dr. Russell Blaylock, Dr. Jerry Kartzinel, writer David Kirby, and ...
... , , BURBANK, ... health expert, Dra. Aliza Lifshitz, announced a partnership today to reach ... Looney Tunes as ambassadors for the program. The partnership will ... to best care for and nurture their babies. Launching in ...
... , , Republicans Losing Confidence ... Sept. 1 According to a 3-year time series analysis of the ... and July 2009), Democrats have increased their ratings on top Latino priority ... , , "This data shows that Congressional ...
... , LOS ANGELES, Sept. 1 Azteca America television ... California gubernatorial candidate Gavin Newsom on the Sept. 1 broadcast of ... Armando Guzman. , , As a self-styled ... plan for universal healthcare and San Francisco is probably the highest ...
... finds , TUESDAY, Sept. 1 (HealthDay News) -- A ... nerve connections failed to improve upon regular laparoscopic surgery ... nerve-disruption procedure "did not alleviate any type of pain…or ... or absence of mild endometriosis," according to the authors ...
... procedure can be done up to 21 hours later with ... News) -- Many people who arrive at hospital emergency rooms ... for artery-opening angioplasty, even if an electrocardiogram (EKG) shows evidence ... There was no significant difference in key measures of heart ...
Cached Medicine News:Health News:Kartzinel, Herbert, Blaylock, Mukhopadhyay and Other Autism Experts Join Keynote Speaker Andrew Wakefield at The 2009 National Autism Conference 2Health News:Video: Renowned Health Expert Dra. Aliza Teams Up With Baby Looney Tunes To Promote Healthy, Happy Babies 2Health News:Video: Renowned Health Expert Dra. Aliza Teams Up With Baby Looney Tunes To Promote Healthy, Happy Babies 3Health News:Video: Renowned Health Expert Dra. Aliza Teams Up With Baby Looney Tunes To Promote Healthy, Happy Babies 4Health News:Congressional Democrats Achieve Credibility With Latino Voters 2Health News:San Francisco Mayor Gavin Newsom Talks About Immigration and Drugs on Azteca America's 'Issues: Caras y Voces' 2Health News:Two Treatments Equally Effective for Chronic Pelvic Pain 2Health News:Sometimes Angioplasty Can Wait 2
(Date:4/24/2015)... , April 24, 2015  Perrigo Company plc ... its rejection of the unsolicited offer from Mylan NV ... the outstanding shares of Perrigo for $60.00 per share ... ordinary Perrigo share (the "Offer").  The ... per share significantly undervalued the Company and its future ...
(Date:4/24/2015)... -- IGI Laboratories, Inc. (NYSE MKT: IG), a ... announced the Company will hold a conference call at ... discuss the 1st quarter 2015 results. The ... dialing 1-888-346-3479. International participants should call 1-412-902-4260. Canadian participants ... into the IGI Laboratories, Inc. call. ...
(Date:4/24/2015)... April 24, 2015  Span-America Medical Systems, Inc. ... its fiscal 2015 second quarter results on Thursday, April ... The company will conduct a conference call ... to review the company,s financial and operating results for ... broadcast of the conference call will be available ...
Breaking Medicine Technology:Perrigo Rejects Mylan Unsolicited Offer 2Perrigo Rejects Mylan Unsolicited Offer 3Perrigo Rejects Mylan Unsolicited Offer 4
... 2011 PDL BioPharma, Inc. (PDL) (Nasdaq: ... McLaughlin, the company,s president and chief executive officer, ... conferences:RBC Capital Markets Healthcare ConferenceWednesday, March 2, 20119:00 ... 31st Annual Health Care Conference Tuesday, March 8, ...
... the leading health care supply contracting company, announced today ... that cover cardiovascular and orthopedic products.  Novation is owned ... and VHA and UHC members represent $2 billion in ... has been in constant contact with Medtronic and has ...
Cached Medicine Technology:Medtronic Inc. Cancels Cardiovascular and Orthopedic Contracts With Novation 2Medtronic Inc. Cancels Cardiovascular and Orthopedic Contracts With Novation 3
... tip has two staggered eyes. It ... Luer fitting adapter is enclosed. They ... left or right. They are for ... opaque. The length is 65cm and ...
Used for drainage and navigation of a tortuous ureter. The tapered tip eases placement as there are no edges to interfere with the ureteral orifice. Supplied sterile in peel-open packages. Intended f...
Used for the retrieval of stones, stents, or other objects in the urinary tract under direct vision. Retrieval Forceps are designed for use through rigid or flexible endoscopes. Supplied sterile in p...
... The ACMI RiteCut Right Angle Cutting ... is used with a general purpose ... for use with any ACMI rigid, ... cystoscope which has a working channel ...
Medicine Products: