Navigation Links
Boston University research suggests new pathways for cancer progression
Date:2/9/2012

BOSTON (2-8-12) Observing that certain cancer cells may exhibit greater flexibility than normal cells, some scientists believe that this capability promotes rapid tumor growth. Now computer simulations developed by Boston University Biomedical Engineering Assistant Professor Muhammad Zaman and collaborators at the University of Texas at Austin appear to support this view. A 3D model of healthy and cancer cells that they've created indicates that the softening of cancer cells not only accelerates their proliferation but also extends their lifetimea one-two punch that may trigger the rapid growth of malignant tumors.

The team's simulations and findings herald a new, quantitative approach to understanding tumor development centered on a small number of mechanical properties rather than multiple biochemical factors.

"Our study is unique in that it takes into account in vivo data on the mechanical properties of cancer cells," said Zaman. "Our novel computer simulation provides a platform to examine how stiffness of cancer cells influences their growth, and could lead to the development of early interventions."

Combining Zaman's expertise in cancer and cell migration with UT-Austin Chemical Engineering Professor Roger Bonnecaze's knowledge of fluid mechanics and postdoctoral fellow Parag Katira's computer simulation skills, the researchers produced a 3D computer model that systematically traces the impact of cell softness and other mechanical factors on cell behavior within a tissue. The model represents each cell as a liquid core encased by a spherical, viscous, elastic shell that can bind or stick to other cells to form a tissue-like mass. In simulations, individual cells are programmed to live, die or divide based on a set of rules drawn from real-time, in vivo experiments with tumor cells.

To emulate tumor growth, the researchers established a baseline simulation of tissue composed exclusively of hard-shelled, healt
'/>"/>

Contact: Mike Seele
mseele@bu.edu
617-353-9766
Boston University College of Engineering
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Boston University researcher awarded 2 NIH grants
2. Dana-Farber/Childrens Hospital Boston study identifies possible therapy for radiation sickness
3. Researchers from Boston University receive grant to develop improved virus detection system
4. Boston researchers share in $10 million grant to study HIV and alcohol
5. Institute for Aging Research study finds Bostons elderly homeless sicker than others
6. Boston Medical Center awarded $1M to expand HIV/AIDS patient care services
7. Boston University School of Medicine professor honored by the Endocrine Society
8. Boston Medical Center chief honored by AUA
9. Boston University researchers validate important roles of iPSCs in regenerative medicine
10. Boston University researchers find most substance-dependent individuals report poor oral health
11. Boston University School of Medicine professor receives award for quality of care research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Boston University research suggests new pathways for cancer progression
(Date:9/30/2014)... Austin, TX (PRWEB) September 30, 2014 ... for Facial Plastic Surgery, has been approved to be ... of Facial Plastic and Reconstructive Surgery (AAFPRS) fellowship program. ... their meeting in Orlando, Florida. , The Educational and ... throughout the medical community. It represents the finest postgraduate ...
(Date:9/30/2014)... September 30, 2014 Gummy teeth ... gum depigmentation treatments for dark gums. Dark gums are ... people feel extremely self-conscious about their smiles. Dr. Farnoosh ... gums. “I am one of the few dental professionals ... have treated celebrities, business leaders, high-ranking officials and patients ...
(Date:9/30/2014)... HealthDay Reporter TUESDAY, Sept. ... supplements won,t prevent the return of a common type of ... In fact, 64.1 percent of those taking fish oil for ... over the course of 16 months, compared to 63.2 ... did not reduce the twin ills of inflammation or oxidative ...
(Date:9/30/2014)... MYERS, Fla. (PRWEB) September 30, 2014 ... Hospital, is giving breast cancer patients a new, more ... surgeries. , Women who undergo mastectomies, biopsies and lumpectomy ... and promote healing. But after seeing her patients describe ... felt compelled to create a new bra in her ...
(Date:9/30/2014)... New York, New York (PRWEB) September 30, 2014 ... will honor Kenro Izu – founder of the nonprofit, ... City on November 6, 2014, for building a hospital ... sustainable pediatric care. , Izu first encountered Cambodia’s ... suffering from a variety of disabilities and illnesses during ...
Breaking Medicine News(10 mins):Health News:Dr. Edward Buckingham Approved to be Fellowship Director for Facial Plastic Surgery 2Health News:Dr. Edward Buckingham Approved to be Fellowship Director for Facial Plastic Surgery 3Health News:Gummy Smile Dentist, Dr. Alex Farnoosh, is Now Offering Gum Depigmentation for Dark Gums 2Health News:Fish Oil Supplements Have Little Effect on Irregular Heartbeat: Study 2Health News:Fish Oil Supplements Have Little Effect on Irregular Heartbeat: Study 3Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 2Health News:Surgeon Creates New Bra for Breast Cancer Patients, Post-Surgery 3Health News:Nobel Prize For Child Advocates Announces 2014 Health Award Honoree 2Health News:Nobel Prize For Child Advocates Announces 2014 Health Award Honoree 3
... WASHINGTON, Sept. 21 Trust for America,s Health ... a new report today featuring a range of evidence-based disease ... reducing costs in communities. , , The ... a summary and examples from an extensive literature review that ...
... , Foundation grants to inspire locally-driven ... PORTLAND, Ore., Sept. 21 The Robert Wood Johnson Foundation ... for Proposal for Partners Investing in Nursing,s Future (PIN), a collaborative ... funding partnerships with local and regional foundations. , ...
... Surgical patients more likely to finish radiation course, study ... and interrupted radiation treatment is a common problem among ... study has found. , Researchers analyzed data from 5,086 ... 1997 and 2003 and found that nearly 40 percent ...
... MD (Sept. 21, 2009) The American Gastroenterological Association ... that the family of the late businessman and photographer, ... a new three-year Research Scholar Award for pancreatic cancer ... Foundation will provide a young investigator with funding and ...
... anyone? Or maybe a big job interview? Dry your palms ... silver lining. Researchers at the Stanford University School of Medicine ... relatively short-term stress can boost the immune system and protect ... this occasional angst seem to last for weeks after the ...
... can blind premature babies are being seen for the first ... Duke University Medical Center. The technology, developed in ... tomography (SD OCT) to create a 3-D picture of the ... way we identify eye conditions in infants," says Cynthia Toth, ...
Cached Medicine News:Health News:New Report Highlights Proven Disease Prevention Programs in Communities 2Health News:New Report Highlights Proven Disease Prevention Programs in Communities 3Health News:New Report Highlights Proven Disease Prevention Programs in Communities 4Health News:Call for Proposals for Partners Investing in Nursing's Future 2Health News:Head, Neck Cancer Treatment Often Not Completed 2Health News:California family honors father with second AGA Foundation Research Scholar Award 2Health News:Short-term stress enhances anti-tumor activity in mice, Stanford study shows 2Health News:Short-term stress enhances anti-tumor activity in mice, Stanford study shows 3Health News:Short-term stress enhances anti-tumor activity in mice, Stanford study shows 4Health News:New device finds early signs of eye disease in preemies 2
(Date:9/29/2014)... -- Repeated exposure to broad-spectrum antibiotics in the first two ... say researchers from The Children,s Hospital of ... data from electronic health records from the extensive CHOP ... children with four or more exposures to broad spectrum ... at risk for obesity. The study, published online September ...
(Date:9/29/2014)... Pharmacists have an important role in ... good clinical trials practices. The Hematology/Oncology Pharmacy Association ... Practice Standards, the first of its kind that ... pharmacists and institutions that conduct clinical trials. The ... the critical role of the pharmacist in the ...
(Date:9/29/2014)... NEW YORK , Sept. 29, 2014 ... Summary GlobalData,s new report, "EU5 ... market data on the EU5 Capsule Endoscopy Systems market. ... volume (in units) and average prices (in US dollars) ... Recorders and Capsule Endoscopy Workstations. The report ...
Breaking Medicine Technology:Antibiotic Use by Age 2 Associated with Obesity Risk 2Antibiotic Use by Age 2 Associated with Obesity Risk 3HOPA Introduces First Investigational Drug Service Best Practice Standards For Institutions And Infusion Clinics 2HOPA Introduces First Investigational Drug Service Best Practice Standards For Institutions And Infusion Clinics 3EU5 Capsule Endoscopy Systems Market Outlook to 2020 2EU5 Capsule Endoscopy Systems Market Outlook to 2020 3
... and Company (NYSE: LLY ) announced the ... Committee voted today to recommend non-approval of liprotamase, a ... review for the treatment of exocrine pancreatic insufficiency (EPI). ... questions about the degree of efficacy of liprotamase and ...
... gloStream, maker of gloEMR and gloPM – the only ... software with Microsoft Office built right in – today announced ... the gloEMR product line. Like its predecessor versions, gloEMR 6.0 ... platform, SQL Server and Microsoft Office so users have access ...
Cached Medicine Technology:Statement From Lilly on FDA Advisory Committee Recommendation Regarding Liprotamase New Drug Application for Treatment of Exocrine Pancreatic Insufficiency 2gloStream Announces Release of Microsoft-Based, Meaningful Use Certified gloEMR 6.0 2gloStream Announces Release of Microsoft-Based, Meaningful Use Certified gloEMR 6.0 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: