Navigation Links
Boston University School of Medicine receives a grant to study chronic obstructive pulmonary disease
Date:12/8/2008

(Boston)-Boston University School of Medicine (BUSM) is one of seven centers to receive a four-year grant from the National Institutes of Health (NIH) to use cutting edge genomic technologies to better understand lung disease. The $2.9 million awarded to BUSM will fund a study to probe the causes of chronic obstructive pulmonary disease (COPD), a disease associated with smoking that is characterized by airflow limitation.

COPD is the fourth leading cause of death in the United States and a significant public health burden. There is currently no cure for COPD, and the limited available therapies are mainly used to treat symptoms of the disease. While the role cigarette smoke plays in COPD is undisputed, the mechanism by which inhaled smoke contributes to disease pathogenesis remains unclear. The purpose of this study is to develop an understanding of the processes that contribute to COPD pathogenesis, ultimately yielding tools for stratifying and treating COPD patients based on the molecular processes that are responsible for their disease.

"One of the major barriers to the development of new approaches to diagnose and manage COPD is the clinical heterogeneity among COPD patients," said principle investigator of the study Avrum Spira, MD, an associate professor of medicine and pathology at Boston University School of Medicine. "We have shown in our previous work that cigarette smoke affects the entire respiratory tract, and that we can detect signs of disease-specific processes occurring deep in the lung by examining, using microarray technology, the pattern of genes that are turned on and off in the relatively accessible cells at the top of the airway. In this study, we will use this approach to help figure out the molecular processes that give rise to COPD in individual patients. Our hope is that this will give us some important clues about what underlies the symptomatic differences seen between patients, and that ultimately we will be abl
'/>"/>

Contact: Allison Rubin
allison.rubin@bmc.org
617-638-8491
Boston University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Boston Micromachines Multi-DM Named One of the Years Most Innovative Products
2. Boston University School of Medicine researcher recipient of Memory Ride Grant
3. Success of Shape-Up Somerville Childhood Obesity Intervention to be Presented at the Friedman School Symposium at Tufts, October 29-31, 2007 - Boston
4. AAHFNs 2008 Annual Meeting in Boston Will Be Raising the Bar in Heart Failure Care
5. Families Invited to Celebrate Shire Day at Boston Childrens Museum
6. Boston Scientific Announces New Initiatives to Increase Shareholder Value
7. Boston Scientific Announces Additions to Clinical Sciences Organization
8. Boston University School of Medicine physician receives award from AATOD
9. Boston Scientific Announces Verdict in Cordis Litigation
10. Boston Scientific Announces Sale of Cardiac Surgery and Vascular Surgery Businesses
11. Boston Scientific and GE Healthcare Announce their First Patient Data Link to Electronic Medical Record
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... ... July 01, 2015 , ... Bunion Bootie, the newest and ... two or more Bunion Booties directly from their website, http://www.BunionBootie.com can ... misaligned toes and its ultra thin properties allow for protection against rubbing footwear ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... firm B. E. Smith, Tri-City Medical Center in Oceanside, Calif., has ... proven record of leading organization-wide compliance adaptation efforts and growing a focus on ...
(Date:7/1/2015)... ... ... The Recovery Workforce Summit: 2015 PRA Annual Conference , presented by ... as a keynote on June 2nd in Philadelphia, PA. Stossel led a timely keynote ... power and reach to the essential message, while opening doors to wellness and recovery. ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... and the Florida Panhandle, the regional southeast Alabama community health system announced ... clinical communications workflow solution provider. TelmedIQ, a burgeoning leader in secure healthcare ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... cannabis space, created a web-based resource where legal cannabis startups can ... together visionary entrepreneurs and medical marijuana advocates looking to strategically enter and capitalize ...
Breaking Medicine News(10 mins):Health News:Bunion Bootie, the #1 Non-Surgical Treatment for Bunion Pain, Announces Their Big Summer Sale 2Health News:Tri-City Medical Center Hires New Chief Compliance Officer 2Health News:Tri-City Medical Center Hires New Chief Compliance Officer 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 2Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 4Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 5Health News:Southeast Alabama Community Health System Chooses TelmedIQ to Meet Secure Text Messaging Challenges for Healthcare 2Health News:First Harvest Financial Partners in Launch of Legal Medical Cannabis Documentary Initiative 2Health News:First Harvest Financial Partners in Launch of Legal Medical Cannabis Documentary Initiative 3
... 2008: Adalimumab therapy is effective and well-tolerated in ... arthritis (PsA) patients with a previously inadequate response ... infliximab, according to results of research presented today ... Rheumatology in Paris, France. This positive response to ...
... China, June 12 /Xinhua-PRNewswire-FirstCall/ -- China Sky One,Medical, ... Medical," "CSY"), a manufacturer,marketer and distributor of pharmaceutical, ... that it has signed an agreement to,acquire Peng ... established,pharmaceutical company that has obtained Good Manufacturing Practice,Certification ...
... Biogen Idec will present data on baminercept alfa ... LIGHT pathway inhibitor in development for the treatment ... the 2008 European League Against Rheumatism (EULAR) Annual ... de Congrs de Paris. Three abstracts will be ...
... Va., June 12 Millions of,Americans are suffering ... struggling with tough economic times, according to a ... alarming new survey,results, patients may wish to consider ... prevention of stress-related headaches and muscle,pain, says the ...
... A few months ago, members of,Congress asked the Social ... approaching retirement age. "A lot of seniors had the,idea ... Cameron,Truesdell, CEO of LTC Financial Partners LLC (LTCFP), one ... insurance agencies. "It wasn,t,so, but the wording of the ...
... history of chronic insomnia in parents is not only ... elevated risks for use of hypnotics, psychopathology and suicidal ... that will be presented on Thursday at SLEEP 2008, ... Societies (APSS). , The study, authored by Xianchen Liu, ...
Cached Medicine News:Health News:Adalimumab therapy effective in AS, RA and PsA patients refractory to other anti-TNF therapies 2Health News:China Sky One Medical, Inc. to Acquire Peng Lai Jin Chuang Company 2Health News:China Sky One Medical, Inc. to Acquire Peng Lai Jin Chuang Company 3Health News:Biogen Idec's baminercept alfa shows promise in patients with rheumatoid arthritis 2Health News:Biogen Idec's baminercept alfa shows promise in patients with rheumatoid arthritis 3Health News:Biogen Idec's baminercept alfa shows promise in patients with rheumatoid arthritis 4Health News:Chiropractic Can Offer Relief from Stress-Related Pain, Health Problems 2Health News:Social Security Statement Advises Seniors to Consider Private Long-Term Care Insurance, LTC Agency Reports; Medicare Won't Cover It 2Health News:Insomnia in parents can result in sleep problems, suicidal behavior among their offspring 2
(Date:7/1/2015)... LOUIS , July 1, 2015 New ... first quarter of 2015 compared to the same time ... the Express Scripts (NASDAQ: ESRX ) Exchange Pulse™ ... first quarter of 2014, the number of new exchange ... declined 18 percent in the first quarter of 2015. ...
(Date:6/30/2015)... EDINBURGH, Scotland , July 1, 2015 ... joins Nu C ana team   ... proprietary ProTide technology to develop and commercialise a portfolio ... Professor Chris McGuigan as Chief Scientific Officer. ... the ProTide technology. He is currently Professor of Medicinal ...
(Date:6/30/2015)... , June 30, 2015 Nortek Security ... NTK ) and a leader in the ... today announced it acquired mobile personal emergency response ... held Numera, Inc. Headquartered in ... easily implemented, mobile PERS products and cloud-based software ...
Breaking Medicine Technology:Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 2Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 4Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 5Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 2Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 4
... 2, 2010 Fiscal first quarter revenue from ... $641 million Fiscal first quarter adjusted income from ... $0.87 per share Fiscal first quarter GAAP income ... per share Rx segment revenue grew 47 percent ...
... IRVINE, Calif., Nov. 2, 2010 Endologix, Inc. (Nasdaq: ... for aortic disorders, announced today the first clinical implant ... City Hospital in Auckland, New Zealand.  The procedure was ... of Interventional Radiology) and Andrew, Hill, MD (Associate Professor ...
Cached Medicine Technology:Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 2Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 3Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 4Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 5Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 6Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 7Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 8Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 9Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 10Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 11Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 12Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 13Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 14Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 15Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 16Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 17Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 18Perrigo Reports Record Earnings and Raises Full Year Adjusted EPS Guidance 19Endologix Announces First Clinical Implant of Ventana™ Stent Graft 2Endologix Announces First Clinical Implant of Ventana™ Stent Graft 3Endologix Announces First Clinical Implant of Ventana™ Stent Graft 4
...
... QUANTA LiteTM ANA is an enzyme-linked ... of anti-nuclear antibodies (ANA) in human serum. ... in conjunction with clinical findings and other ... of rheumatic diseases such as systemic lupus ...
... Immuno Concepts manufactures slides that are ... technologist to decrease the number of pipetting ... patient sample dilutions on the slides. Ask ... procedure and these slides. These slide formats ...
... The ANA and ENA assays can ... negative for antinuclear antibodies, which are ... such as Systemic lupus erythematosus (Lupus), ... progressive systemic sclerosis, scleroderma, polymyositis, dermatomyositis, ...
Medicine Products: