Navigation Links
Boston University School of Medicine awarded grants to improve early detection of lung cancer
Date:12/14/2010

(Boston)- Researchers from Boston University School of Medicine (BUSM) have been awarded a five-year, $2 million grant from the National Cancer Institute (NCI) Early Detection Research Network (EDRN), as well as a four-year, $1.3 million grant from the Department of Defense (DOD). These grants will allow the scientists to develop novel and complementary procedures for early detection of lung cancer in high-risk patients.

The grant from NCI will support collaboration between the University of California-Los Angeles and Boston University to form a Lung Cancer Biomarker Development Laboratory (UCLA-BU BDL) as part of the NCI EDRN program. The focus of the Boston University portion of this research program is designed to develop new tests for diagnosing lung cancer based on subtle cancer-related differences in cells from the nose or mouth.

"The idea is that even though these cells aren't cancerous, they act differently in patients with cancer and we can use these differences to diagnose disease," said Marc Lenburg, PhD, one of the principal investigators on the grant and an associate professor of medicine and pathology at BUSM.

The Boston University researchers will use sophisticated genomic approaches that measure the activity of each gene to detect the differences between patients with and without cancer. By drawing from the vast academic and clinical resources at the two institutions, the UCLA-BU BDL will advance new discoveries and transform them into early detection tools for lung cancer.

The DOD grant will fund collaborative research involving researchers at Boston University, UCLA, MD Anderson, and Vanderbilt University. This project also focuses on novel tests for the early detection of lung cancer, and will study veterans. Veterans are 75 percent more likely to develop lung cancer than civilian adults and also more likely to die from the disease.

The researchers will collect cells from the airways of veterans that have been damaged by smoking and develop a test that can detect differences in the healing of these injuries that might be related to lung cancer. This could ultimately allow for the detection of early signs of lung cancer in cells from the mouth, nose and throat that can be easily collected from smokers at risk for developing the disease. The work will further research into how lung cancer develops and on novel cancer therapies that target this process.

"The challenge is to develop lung cancer detection methods that are effective during this early window of opportunity to increase the rate of early detection and thereby spur early treatment and improve lung cancer patient outcomes," said Avrum Spira, MD, principal investigator on both grants and an associate professor of medicine and pathology at BUSM.


'/>"/>

Contact: Nathan Bliss
nathan.bliss@bmc.org
617-638-8490
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Boston University researcher lauded for leading-edge lung cancer research efforts
2. Boston, Oct. 21-24: Largest international pediatric oncology conference
3. Boston Medical Center receives 2 grants for integrative medicine research
4. Boston Medical Center research study validates the Boston Bowel Preparation Scale
5. eMindful Provides a New Twist on Chocolate for Members of Boston's Beacon Hill Village
6. 25th AIDS Walk Boston to Take Place Sunday, June 6, 2010
7. Boston Children's Museum Lunch & Learn Lecture Series
8. Village at Proprietors Green Opens on South Shore, Introducing Innovative Senior Living to Boston Area
9. Vietnamese Student Named UMass Boston JFK Award Winner
10. Save the date: American Chemical Society National Meeting in Boston, Aug. 22-26
11. Keeping the Boston Bruins Healthy. Their New - Very Cold - Secret Weapon Against Injuries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/6/2016)... ... February 06, 2016 , ... FOR INFORMATION: ... AORN SURGICAL CONFERENCE & EXPO , WHAT:     , This conference is the ... perioperative nurses in attendance to study the latest evidence-based recommendations and resources ...
(Date:2/6/2016)... ... February 06, 2016 , ... Research has shown ... to reduce the frequency and level of relapse. , At the ... and Purpose,” will explore the critical tasks of the recovery phase and beyond ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Today, the Whole-Food ... announced that the much-anticipated feature with author Jahnavi Foster, specialist in healthy vegetarian cuisine, ... Network. , Each week, on his weekly Whole-Food Warrior TV show, Frank Davis highlights ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... ... announce the addition of micro-needling services in their Napa Valley office. The technique ... of Plastic Surgery Associates, Dr. Canales and Dr. Furnas, are part of only ...
(Date:2/5/2016)... ... February 05, 2016 , ... The ... funding innovative lymphoma research and serving the lymphoma community through a comprehensive series ... again host, Swirl, A Wine Tasting Event at the La Gorce Country Club ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... SAN DIEGO , Feb. 5, 2016 Aethlon ... Jim Joyce , Chairman and CEO, will be presenting at ... New York, NY at 2:15 p.m. ... participate in an Immunotherapy Panel discussion taking place at 3:15 ... available for replay approximately one hour after the conclusion of ...
(Date:2/5/2016)... February 5, 2016 --> ... report states that the global active pharmaceuticals ingredients (APIs) ... predicted to reach US$185.9 bn by 2020. It is ... 2014 to 2020. The title of the report is ... by Geography, and by Therapeutic Area) - Global Industry ...
(Date:2/5/2016)... 5, 2016  Zimmer Biomet Holdings, Inc. (NYSE and ... announced underwritten secondary offering of 11,027,558 shares of its ... affiliates of Blackstone and Goldman Sachs.  The shares are ... of $96.45 per share. The selling stockholders will receive ... Biomet nor any of its directors, officers or other ...
Breaking Medicine Technology: