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Boston Scientific PROMUS(R) and First-Generation TAXUS(R) Express(R) Stents Continue Excellent Performance in SPIRIT III Trial
Date:9/21/2009

buting to a benefit for XIENCE V (PROMUS) over the TAXUS Express Stent in the composite endpoints of Major Adverse Cardiac Events (MACE, a composite endpoint of Cardiac Death, Myocardial Infarction (MI) and TLR) (9.1% versus 15.7%, p=0.003) and Target Vessel Failure (TVF, a composite endpoint of Cardiac Death, MI and Ischemia-Drive Target Vessel Revascularization) (13.5% versus 19.2%, p=0.03).

The SPIRIT III results exhibited similar rates of safety and efficacy for the XIENCE V (PROMUS) and TAXUS Express Stents in diabetic patients, with TLR rates of 5.2% versus 4.8% and MACE rates of 10.3% versus 9.4%. The rate of TLR for TAXUS Express diabetic patients was 4.8 percent as compared to 10.5 percent in non-diabetic TAXUS Express patients.

"It is noteworthy that the rate of TLR - which was equivalent for PROMUS and TAXUS Express in diabetic patients - was actually lower in diabetic patients treated with TAXUS Express than in non-diabetics treated with TAXUS Express," added Dr. Baim.

The PROMUS Stent is a private-labeled XIENCE V Everolimus-Eluting Coronary Stent System manufactured by Abbott and distributed by Boston Scientific. SPIRIT III is sponsored by Abbott. TAXUS, TAXUS Express2, Express and PROMUS are trademarks of Boston Scientific Corporation or its affiliates. XIENCE is a trademark of Abbott Laboratories Group of Companies.

The safety and effectiveness of the TAXUS Express Stent has not been established in diabetic patients.

Boston Scientific is a worldwide developer, manufacturer and marketer of medical devices whose products are used in a broad range of interventional medical specialties. For more information, please visit: www.bostonscientific.com.

Cautionary Statement Regarding Forward-Looking Statements

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