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Boston Scientific PROMUS(R) and First-Generation TAXUS(R) Express(R) Stents Continue Excellent Performance in SPIRIT III Trial
Date:9/21/2009

NATICK, Mass. and SAN FRANCISCO, Sept. 21 /PRNewswire-FirstCall/ -- Boston Scientific Corporation (NYSE: BSX) today welcomed three-year results from the SPIRIT III clinical trial, which continue to reaffirm the proven long-term safety of the Company's portfolio of drug-eluting stents, including the first-generation TAXUS((R)) Express(2)(TM) Paclitaxel-Eluting Coronary Stent System and the XIENCE V(TM) (PROMUS((R))) Everolimus-Eluting Coronary Stent System. The results were presented at the Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium in San Francisco by Gregg W. Stone, M.D., Professor of Medicine and the Director of Research and Education at the Center for Interventional Vascular Therapy at the Columbia University Medical Center/New York-Presbyterian Hospital, and Principal Investigator of the trial.

"We are very pleased that our first-generation TAXUS Express Stent continued to perform well against our PROMUS Stent in the SPIRIT III trial at three years," said Donald S. Baim, M.D., Chief Medical and Scientific Officer of Boston Scientific. "The strong outcomes among diabetic patients were particularly impressive."

The results demonstrated that the XIENCE V (PROMUS) and TAXUS Express Stents had comparable safety outcomes through three years, with equivalent rates of cardiac death (1.4% versus 1.6%, p=0.68) and low and equivalent rates of stent thrombosis using the ARC (Academic Research Consortium) definite/probable definition (1.2% and 1.6%, p=0.67). No additional stent thromboses were reported between years two and three for either stent group.

The three-year rate of Ischemia-Driven Target Lesion Revascularization (TLR) was lower for the XIENCE V (PROMUS) Stent as compared to the TAXUS Express Stent (5.4% versus 8.9%, p=0.05), contri
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SOURCE Boston Scientific Corporation
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