Navigation Links
Boosting the efficacy of anticancer vaccines
Date:8/2/2010

There are several challenges to be overcome if therapeutic anticancer vaccines, which are designed to boost the patient's anticancer immune response, are to be successfully developed. For example, the viruses used to deliver the tumor protein to the patient's immune system are themselves targeted by the patient's immune system, inducing neutralizing and suppressive responses. But now, a team of researchers, led by Michael Morse, at Duke University Medical Center, Durham, has developed a way to overcome these neutralizing and suppressive responses by using an alphavirus packaged in virus-like replicon particles. Repeated administration of such particles carrying the tumor protein CEA to patients with metastatic cancer expressing CEA induced clinically relevant immune responses targeted to CEA. As the presence of such immune responses was associated with longer overall patient survival, the authors hope their approach might be of therapeutic use in many cancer settings.


'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Boosting Mental Performance, from the Harvard Mental Health Letter
2. The Diet Solution Program: Popular Online Weight Loss Program is Revised to Include More Metabolism Boosting Meals
3. Smoking Bans May Be Boosting Public Health
4. Boosting Vitamin D Can Do a Heart Good
5. Free Brain IQ Quiz, Activities for Home “Brain-Boosting” and Seminar Offered from LearningRX Denver during National Brain Awareness Month
6. Smoking cigarettes is a predictor of RA and may negatively impact on efficacy of anti-TNFs
7. Sleep apnea patients using oral appliance therapy show high efficacy and compliance
8. 14 Human Clinical Studies Prove the Efficacy of Tahitian Noni Bioactive Beverages
9. EXCEL trial will determine safety and efficacy of drug-eluting stents vs. bypass surgery
10. COPPERTONE(R) Solar Research Center Unveils Studies on Efficacy of Topical Antioxidants in Sunscreens at 2010 Annual Meeting of The American Academy of Dermatology
11. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... , ... “The Trainer”: an electrifying and suspenseful gunslinger novel with a ... an active imagination and an enthusiasm for action and adventure stories. , ... Hart, who sat looking at the thirty-three notches that lined the edges of the ...
(Date:3/22/2017)... ... March 22, 2017 , ... Cosmetic Town, an online plastic ... its companion print magazine. The new magazine, scheduled for release in mid-April, includes ... by board-certified doctors from across the country. , According to the senior editor ...
(Date:3/22/2017)... ... 22, 2017 , ... The American Society for Preventive ... form for prescribers to improve patients’ access to the revolutionary therapy for appropriate ... part of the article entitled “PCSK9 Inhibitor Access Barriers: Issues and Recommendations: ...
(Date:3/22/2017)... ... March 22, 2017 , ... In recognition of Colon Cancer ... focused on cancer patients, cancer centers and advocacy groups, and MJH Studios™, a ... series, “No Ifs, Ands, or Butts,” that focuses on Colorectal Cancer detection, prevention ...
(Date:3/22/2017)... ... March 22, 2017 , ... An intensive search of the medical ... reports Leslie Norins, MD, PhD. He says investigating this possibility, is important ... virus and in new infections with HIV. , His findings appear on ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... 2017 Serve You Rx Vermont, LLC, a wholly ... You), based in Milwaukee, Wisconsin , has ... in Middlebury, Vermont , from Pharmacy Health ... so it was perfect timing for this opportunity to present ... Serve You. "Like us, NEMOP has a high-touch service model, ...
(Date:3/22/2017)... , Mar 22, 2017 Research ... Immune Check Point Inhibitors Market & Clinical Pipeline Insight 2022" ... ... Inhibitors Market & Clinical Pipeline Insight 2022 report gives comprehensive ... and integration of immune check point inhibitors as main streamline ...
(Date:3/22/2017)... , March 22, 2017 ... Manufacturing Organization (CDMO), held a special event to introduce ... in Lexington, Kentucky . The inaugural ... Piramal Group Chairman Ajay Piramal, and Piramal Pharma ... ...
Breaking Medicine Technology: