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Bone marrow stem cell co-transplantation prevents embryonic stem cell transplant-associated tumors
Date:5/11/2009

," says Dr. Yoshikawa. "We considered that the BMSCs played an important role in preventing tumors and speculate that one of the mechanisms by which BMSCs promote the differentiation of ES cells is related to secreted soluble factors, including neurotrophic factors."

According to Dr. Yoshikawa, the transplanted BMSCs survived in the grafted site for at least five weeks after transplantation and maintained their ability to produce NGF.

"These findings are extremely important and emphasize the need for additional study on how embryonic stem cells may be used to treat human neurological problems in the not too distant future," commented Section Editor Dr. John Sladek, professor of pediatrics and neuroscience at the University of Colorado School of Medicine.


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Contact: Dr. Masahide Yoshikawa
myoshika@naramed-u.ac.jp
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

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