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Bone from blood: Circulating cells form bone outside the normal skeleton, Penn study finds
Date:7/23/2009

FOP patients that had formed new bone, and found that these cells had migrated into the early sites of the lesion.

"This study provides an explanation for how bone-forming cells could seed sites of injury and inflammation that subsequently develop ossifications outside the skeleton," says Frederick S. Kaplan, MD, Isaac & Rose Nassau Professor of Orthopedic Molecular Medicine and Director of the Center for FOP & Related Disorders at Penn. "Dr. Pignolo and researchers in his lab demonstrated that these circulating cells are able to home to damaged tissue."


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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert  

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