Navigation Links
Bone drug suppresses wandering tumor cells in breast cancer patients
Date:6/2/2010

r received a combination treatment of chemotherapy and zoledronic acid.

After three months of therapy, patients with DTCs in their bone marrow decreased from 43 percent to 30 percent in the combination group, compared with a decrease from 48 percent to 47 percent in the control group. This result approached statistical significance.

The researchers also found that of those patients who had no DTCs in their bone marrow at the start of the study, 87 percent remained negative after three months of combination treatment compared to 60 percent of those who received chemotherapy alone, a result that was statistically significant.

Zoledronic acid treatment with chemotherapy had additional benefits. Women in the combination group experienced significant gains in bone density after 12 months. This is helpful for breast cancer patients, who often develop osteoporosis as a side effect of chemotherapy and other breast cancer treatments.

The study also suggested that zoledronic acid may help fight certain types of breast tumors directly. Aft speculates that the drug may stop the tumor from making its own blood supply, modify the immune system in a way that makes it harder for tumor cells to survive or even cause the cancer cells to commit suicide.

"Although it's common practice to administer zoledronic acid during chemotherapy given after breast cancer surgery, it isn't common when chemotherapy is given before surgery," Aft says. "Because chemotherapy increases bone loss, we would argue that women should receive zoledronic acid at the time of chemotherapy in the presurgical setting. Our single-institutional study also suggests that similar protocols using zoledronic acid for high-risk breast cancer patients should continue to be tested in larger, multi-institutional studies."


'/>"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. FreightWatch Security Net Launches Solution for Tracking and Rescuing Persons at Risk of Wandering
2. Spice Compounds May Stem Tumor Growth
3. New Scan May Help Find Aggressive Prostate Tumors
4. CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth
5. American Brain Tumor Association names Alexander Ksendzovsky outstanding 2009 medical student
6. Scientists show how brain tumors outsmart drugs
7. Researchers find a treatment for deadly brain tumor
8. Cancer stem cells suppress immune response against brain tumor
9. Florida Brain Tumor Association & Moffitt Cancer Center Presents: The Bridge to Hope
10. Diffusion tensor imaging increases ability to remove benign tumors in children
11. Minimally invasive surgery removes sinus tumor without facial disfiguration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bone drug suppresses wandering tumor cells in breast cancer patients
(Date:8/21/2014)... not protest being overcompensated, even when there are ... and Behavior Program have found. , This could ... believed about the inequity of others, researchers said. ... Brain Connectivity . These findings suggest humans, sense ... the interest humans show in others, outcomes is ...
(Date:8/21/2014)... Home Care Assistance of Centennial ... that it has received the Certified – Trusted Provider ... Care Assistance’s commitment to client satisfaction. , “Our goal ... client’s in the South Metro Denver area are receiving ... of Home Care Assistance of Centennial. “Home Care ...
(Date:8/21/2014)... and health authorities need to ensure that experimental drugs ... context of randomized controlled trials, according to a new ... 21 August, 2014]. , Leading bioethicists Professor ... and Dr Annette Rid, of King,s College London, UK, ... to if experimental drugs are to be deployed in ...
(Date:8/21/2014)... CA (PRWEB) August 21, 2014 ... of American Corporate Health, was recently recognized ... influential professionals in the field of workers’ ... National Workers’ Compensation and Occupational Medicine Conference ... including attorneys, physicians, nurses, case managers, disability ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 According to ... "Medical Fiber Optics Market-Global Industry Analysis, Size, Share, Growth, ... fiber optics market was valued at USD 863.1 million ... CAGR of 7.6% from 2013 to 2019, to reach ... , The medical fiber optics market is witnessing significant ...
Breaking Medicine News(10 mins):Health News:Influenced by self-interest, humans less concerned about inequity to others 2Health News:Influenced by self-interest, humans less concerned about inequity to others 3Health News:Home Care Assistance of Centennial Receives Home Care Pulse Certified – Trusted Provider Distinction 2Health News:Home Care Assistance of Centennial Receives Home Care Pulse Certified – Trusted Provider Distinction 3Health News:The Lancet: Experimental Ebola drugs must be fairly distributed and tested ethically in clinical trials 2Health News:Dr. Vasili Gatsinaris Named One of the Top 50 Most Influential in Workers’ Compensation 2Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 2Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 3Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 4
... recurrence of breast cancer shows promise in fighting life-threatening ... born prematurely and patients with cancer. Some scientists suspected ... the University of Rochester Medical Center shows that it ... disease. "It,s still early, but if tamoxifen, or ...
... ... to share their experiences and tips on keeping kids healthy and active this summer ... Minneapolis, MN (PRWEB) July 20, ... and television aside as they enjoy the summer sun. While the occasional bump or bruise ...
... , , Stronger ... WASHINGTON, July 20 Five organizations representing the nation,s ... public health and disease prevention announced their support for a provision ... within the healthcare reform bill introduced by leaders of the U.S. ...
... July 20 The following was released today by Randall Terry, founder of Operation ... discussing potential backlash -- including the potential of unwanted violence -- if Congress votes ... Address: National Press Building, 529 14th Street NW, Washington, DC , ... , Leaders to be present: , , ...
... , , ... Competition between employer-based health insurance plans and a government-sponsored public ... the majority of employers responding to a Health Care Reform Survey, ... Aon Corporation (NYSE: AOC ). What will help ...
... , , , ... CareFusion Corporation, the company that will become publicly traded following ... of Cardinal Health, today announced it has expanded its Pyxis((R)) ... (ORIS), incorporate radio-frequency identification (RFID) technology(1) and include new services. ...
Cached Medicine News:Health News:Breast cancer drug shows promise against serious infections 2Health News:Treating Kids' Summertime Bumps, Bruises and Injuries with The Healthcare Scoop 2Health News:Treating Kids' Summertime Bumps, Bruises and Injuries with The Healthcare Scoop 3Health News:Experts Support National Public Reporting of Healthcare-Associated Infections 2Health News:Experts Support National Public Reporting of Healthcare-Associated Infections 3Health News:Employers Express Doubts About Employer Mandate and Government-Sponsored Public Plan, Says Aon Consulting Survey 2Health News:Employers Express Doubts About Employer Mandate and Government-Sponsored Public Plan, Says Aon Consulting Survey 3Health News:Employers Express Doubts About Employer Mandate and Government-Sponsored Public Plan, Says Aon Consulting Survey 4Health News:Employers Express Doubts About Employer Mandate and Government-Sponsored Public Plan, Says Aon Consulting Survey 5Health News:CareFusion Expands Pyxis(R) Perioperative Solutions Offering 2Health News:CareFusion Expands Pyxis(R) Perioperative Solutions Offering 3Health News:CareFusion Expands Pyxis(R) Perioperative Solutions Offering 4Health News:CareFusion Expands Pyxis(R) Perioperative Solutions Offering 5
(Date:8/20/2014)... , Aug. 20, 2014 Northstar Global ... that after months of hard work from many ... new Snorenz formulation and package design.  The new ... B-6 back into the product due to overwhelming ... lasting effects.  Snorenz Nighttime will also include these ...
(Date:8/20/2014)... Md. , Aug. 20, 2014  The ... lauded the latest results achieved by the real-time, ... as the National Precursor Log Exchange (NPLEx), automatically ... officials track down methamphetamine offenders and make arrests. ... Michigan blocked the sale ...
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com ... is available in its catalogue: ... Key Trends and Opportunities to 2017 ... Synopsis The report provides in depth ... Canadian personal accident and health insurance segment, ...
Breaking Medicine Technology:Northstar completes the first phase of its new retail strategy and prepares to ship reformulated Snorenz with all new packaging 2Michigan's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23
Redesigning the World's Oxygen Therapy One Device at a Time. , ,Everything you like about our OXYMATIC 400 Series conservers, only better!...
... Accutrol is similar in design to the ... incorporates a temperature probe at the tip ... can accurately determine the patient's core body ... accuracy comparable to a pulmonary artery catheter ...
... Ultra Micro Shafts For Insertion Through ... For Light-Weight ... ,Curved Shafts For A More Comfortable Approach., ... ,Protective Cap Supplied For Protection Of Jaws ...
The New Easy-To-Use Disposable Diamond Knife Cleaning System Can Remove Even Baked-On Debris In Seconds. It Is Much More Effective Than Steam Or Blocks Of Styrofoam, Much Safer For Employees As Wel...
Medicine Products: