Navigation Links
Bone Marrow Cancer Patients May Benefit From Drug Combo
Date:3/29/2010

Small study had successful results in myelodysplastic syndrome patients

MONDAY, March 29 (HealthDay News) -- The drugs azacitidine and lenalidomide provide a highly effective combination treatment for bone marrow cancer, according to the results of a new study.

The phase 1 study, which was funded by the U.S. National Institutes of Health, included 18 higher-risk patients, median age 68, with myelodysplastic syndromes (MDS). In people with this cancer (which is similar to leukemia), stem cells fail to mature into healthy red blood cells, white blood cells or platelets. This leads to infection, anemia and bleeding complications.

The patient response rate to the combined drug treatment was 67 percent, and the treatment was well-tolerated. The combined treatment had a better response rate and remission rate than either drug used alone.

This is the first time that two U.S. Food and Drug Administration-approved drugs have been combined for the treatment of MDS. The findings were published online March 29 in the Journal of Clinical Oncology.

"This combination was so successful, it's being incorporated into the next nationwide MDS study, as well as international studies," study author Dr. Mikkael Sekeres, of the Taussig Cancer Institute at the Cleveland Clinic, said in a news release.

About 15,000 people are diagnosed with MDS each year in the United States, and about 60,000 are living with the disease. MDS primarily affects older adults.

More information

The American Cancer Society has more about myelodysplastic syndromes.



-- Robert Preidt



SOURCE: Cleveland Clinic, news release, March 29, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Stem Cell, Bone Marrow Transplants Both Benefit Leukemia Patients
2. Stem cell breakthrough: Bone marrow cells are the answer
3. Bone Marrow Transplants May Cure Sickle Cell in Adults
4. Mayo Clinic Proceedings: Researchers find evidence of survival gains in bone marrow disease
5. Drug dramatically reduces nausea and vomiting in bone marrow transplant patients
6. HIV Hides Out in Bone Marrow Cells
7. University of Michigan scientists discover bone marrow can harbor HIV-infected cells
8. Fewer platelets could be used for some cancer and bone-marrow transplantation patients
9. Autologous Bone Marrow Stem Cells Transplant into Parkinson's Disease Patients is Safe and May Improve Their Quality of Life
10. Vertebroplasty: Integral to treating back pain in blood marrow cancer patients
11. Targeted therapy prolongs life in patients with HER2-positive breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
Breaking Medicine Technology: