Navigation Links
Bone Marrow Cancer Patients May Benefit From Drug Combo
Date:3/29/2010

Small study had successful results in myelodysplastic syndrome patients

MONDAY, March 29 (HealthDay News) -- The drugs azacitidine and lenalidomide provide a highly effective combination treatment for bone marrow cancer, according to the results of a new study.

The phase 1 study, which was funded by the U.S. National Institutes of Health, included 18 higher-risk patients, median age 68, with myelodysplastic syndromes (MDS). In people with this cancer (which is similar to leukemia), stem cells fail to mature into healthy red blood cells, white blood cells or platelets. This leads to infection, anemia and bleeding complications.

The patient response rate to the combined drug treatment was 67 percent, and the treatment was well-tolerated. The combined treatment had a better response rate and remission rate than either drug used alone.

This is the first time that two U.S. Food and Drug Administration-approved drugs have been combined for the treatment of MDS. The findings were published online March 29 in the Journal of Clinical Oncology.

"This combination was so successful, it's being incorporated into the next nationwide MDS study, as well as international studies," study author Dr. Mikkael Sekeres, of the Taussig Cancer Institute at the Cleveland Clinic, said in a news release.

About 15,000 people are diagnosed with MDS each year in the United States, and about 60,000 are living with the disease. MDS primarily affects older adults.

More information

The American Cancer Society has more about myelodysplastic syndromes.



-- Robert Preidt



SOURCE: Cleveland Clinic, news release, March 29, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Stem Cell, Bone Marrow Transplants Both Benefit Leukemia Patients
2. Stem cell breakthrough: Bone marrow cells are the answer
3. Bone Marrow Transplants May Cure Sickle Cell in Adults
4. Mayo Clinic Proceedings: Researchers find evidence of survival gains in bone marrow disease
5. Drug dramatically reduces nausea and vomiting in bone marrow transplant patients
6. HIV Hides Out in Bone Marrow Cells
7. University of Michigan scientists discover bone marrow can harbor HIV-infected cells
8. Fewer platelets could be used for some cancer and bone-marrow transplantation patients
9. Autologous Bone Marrow Stem Cells Transplant into Parkinson's Disease Patients is Safe and May Improve Their Quality of Life
10. Vertebroplasty: Integral to treating back pain in blood marrow cancer patients
11. Targeted therapy prolongs life in patients with HER2-positive breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... treat children with uncomplicated acute appendicitis is a reasonable ... fewer missed school days, according to a pilot study. ... Hospital and published online April 12 in the ... the first prospective study on nonoperative management of acute ... , Researchers enrolled 77 patients age 7 to 17 ...
(Date:4/14/2014)... 2014, Perth, Australia. Drug discovery company Proteomics International ... of a companion diagnostic (CDx) test with the ... The research team authenticated the panel of biomarkers ... samples. Seven biomarkers were validated at high stringency ... The mass spectrometry data was then cross-validated using ...
(Date:4/14/2014)... 2014) When it comes to the cost and ... Patients get the best care when they are treated ... extensive experience in their current job, according to a ... and Columbia Business School. The study was published in ... Applied Economics . , The review of more ...
(Date:4/13/2014)... STANFORD, Calif. A low-cost empowerment program for ... and sexual harassment of these girls, who live ... and are frequently attacked, a large new study ... Stanford University School of Medicine, Lucile Packard Children,s ... No Worldwide, validated the program,s effectiveness in combating ...
(Date:4/11/2014)... the processes that control brain cell production could pave ... brain-related disorders. , Scientists have gained new understanding of ... how and when nerve and brain cells are formed ... and keeps it healthy. Their findings could help explain ... which is a fundamental characteristic of many diseases including ...
Breaking Medicine News(10 mins):Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 2Health News:Antibiotics alone are a successful treatment for uncomplicated acute appendicitis in kids 3Health News:Longer nurse tenure on hospital units leads to higher quality care 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 2Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 3Health News:Empowerment program greatly decreases incidence of rape, Stanford/Packard-led study finds 4
... (Nov. 8, 2011) - Patients who are not ... lesions could be treated with carotid artery stenting, according ... at The University of Texas Health Science Center at ... by lead investigator Colin M. Barker, M.D., at the ...
... , TUESDAY, Nov. 8 (HealthDay News) -- The reversal ... of receiving a new organ from a deceased donor, U.S. ... Sharing (UNOS) gave priority to potential recipients who had a ... an antigen involved in the body,s immune response to foreign ...
... on Dec. 1, University of Cincinnati research is shedding light ... AIDS and HIV infections. An Ohio survey conducted by Matthew ... AIDS remains a public health concern. Asare surveyed just ... AIDS/HIV and sex all subjects that are considered taboo ...
... Smoking bans in public places have had a spillover effect ... new study. U.S. researchers analyzed data from a nationally ... who lived in counties with total smoking bans in workplaces, ... bans at home. Homes with children were most likely ...
... TUESDAY, Nov. 8 (HealthDay News) -- New research finds older ... than younger women, suggesting that older patients may not be ... over the past three decades. Researchers analyzed U.S. government ... death rates were stable throughout the 1980s for women aged ...
... it sounds like good news: The body,s own immune ... not necessarily for the benefit of the patient. "We ... Professor Dr. Viktor Umansky, immunologist at DKFZ and University ... the immune system specifically attack tumor cells. On the ...
Cached Medicine News:Health News:Racial Disparities Still Exist for Kidney Recipients, Study Finds 2Health News:Survey finds that AIDS remains an unspeakable subject for African immigrants 2Health News:Public Smoking Bans May Spill Over to Households 2Health News:Advances in Breast Cancer Care May Not Be Reaching Older Women 2Health News:Using Viagra to combat malignant melanoma 2
(Date:1/15/2014)... , Jan. 15, 2014  Research and Markets ... the "Dental Consumables Market - Global Industry ... - 2018" report to their offering. ... ) Dental consumables are products which are ... impairments, for tooth restoration and in treatment of ...
(Date:1/15/2014)... , Jan. 15, 2014  Novation, the leading ... company, awarded several new IT value-added reseller (VAR) ... hospital organizations with IT goods and services at ... agreements, as well as value-added services such as ... New Novation agreements were awarded to ...
(Date:1/15/2014)... DUBLIN , January 15, 2014 ... that it has waived the Office of Fair Trading (OFT) ... the outstanding shares of ViroPharma Incorporated (NASDAQ: VPHM).   ... no longer conditional on OFT approval, and Shire expects to ... currently scheduled expiration time, subject to the satisfaction of all ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... Cryo System is the first in portability and performance. ... surgeons who need a flexible, portable system with the ... CTU attaches easily to an "E" size tank and ... cryo to where it is needed.,The CTU Travel Case ...
... easy-to-use, workflow-based system designed to save you time ... the SleepWorks software and either the Connex or ... can be used for a complete range of ... EEG recording - and have superior signal quality ...
... made up of three integral components including ... Merci Balloon Guide Catheter. The system employs ... the clot has been identified using angiography, ... through a small incision in the femoral ...
... level of care you can provide to ... care program, including innovative products, standardization and ... Davol® pulsed lavage systems deliver the performance ... tissue, bacteria, and foreign material. Each provides ...
Medicine Products: