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Boehringer Ingelheim Plans to Launch U.S. Registry to Assess the State of Anticoagulation Therapy for Stroke Prevention in Patients with Non-Valvular Atrial Fibrillation
Date:3/31/2009

tients with AF who are treated in ordinary community medical practices.

In this registry, Boehringer Ingelheim plans to enroll 1,500 AF patients prospectively at roughly 250 general and cardiology practices across the country.(1) In addition, retrospective data will be analyzed from 1,000 patients from the same clinical sites.(1) The registry is designed to provide a better understanding of patient characteristics and risk factors, clinical outcomes (e.g., ischemic stroke, other thromboembolic events and bleeding) and healthcare resource utilization associated with the initiation of anticoagulation treatment in non-valvular AF.(1)

Analyses of retrospective data, including a medical claims database review presented today at the 58th Annual Scientific Session of the American College of Cardiology (ACC) in Orlando, FL, suggest that many patients with AF who are potentially eligible for anticoagulation therapy for stroke prevention are not treated.(7,8) The data from REAL-AF should contribute to our understanding of current treatment trends.

Claims Database Review

A Boehringer Ingelheim sponsored, retrospective analysis of medical claims from a nationally representative group of U.S. managed care plans (from January 2001 to December 2006), was presented today at ACC. The analysis of data from more than 50,000 patients with atrial fibrillation not associated with valvular disease found that less than half (41.9%) of patients potentially eligible for anticoagulation therapy for stroke prevention received it.(7) Patients were considered eligible for anticoagulant therapy if they were at moderate to high risk for stroke and lacked any evidence of contraindication to treatment.(7)

"This medical claims database review found that anticoagulation therapy was not used as widely or effectively as it could have been for stroke prevention in atrial fibrillation patients," said Dr.
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SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
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