Navigation Links
Body's Response to Foods' Smell, Taste Could Be Diabetes Risk Factor
Date:3/11/2010

A gene mutation could trigger key insulin reaction in some, researchers say

THURSDAY, March 11 (HealthDay News) -- A mutation that affects how the body responds when a person smells or tastes food may play a role in the development of type 2 diabetes in some people, U.S. researchers report.

"Our study showed there is a novel genetic mutation through which some type 2 diabetic people could be vulnerable to the gradual onset of this disease," study senior author Vann Bennett, a professor in the departments of cell biology, biochemistry and neurobiology at Duke University Medical Center, said in a news release from the school.

He said this gradual development of diabetes "happens through what is called the parasympathetic nervous system, not directly through eating food. We think this parasympathetic response is potentially very important in type 2 diabetes."

When people eat or smell food, their bodies begins to secrete insulin. A molecule called ankyrin B plays an important role in insulin response.

Experiments with mice lacking the molecule showed that ankyrin B deficiency impairs the parasympathetic chain of events that lead to insulin secretion. This has a measurable effect on blood sugar levels.

Further investigation revealed that one type of mutation in ankyrin B was associated with type 2 diabetes in Hispanics and whites.

The study was published online March 11 in the journal Science Signaling.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about type 2 diabetes.



-- Robert Preidt



SOURCE: Duke University, news release, March 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
2. Study identifies key player in the bodys immune response to chronic stress
3. Retired NYPD Lieutenants William E. Keegan, Jr., Owen McCaffery and John Moran and Tom Thees, a former COO in the financial industry, announce today the formation of H.E.A.R.T (Healing Emergency Aid Response Team) 911.
4. Response Biomedical appoints S. Wayne Kay Chief Executive Officer
5. Merck & Co., Inc. Response to Todays New York Medicaid Suit
6. Maternal depression and controlling behavior associated with increased stress response in infants
7. Family history of alcoholism affects response to drug used to treat heavy drinking
8. Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
9. Breast cancer susceptibility gene predicts outcome and response to treatment in lung cancer
10. PET scans can accurately detect a breast tumors response to chemotherapy
11. DNA damage response confers a barrier for viral tumorigenesis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... March 23, 2017 , ... The TouchPoint Solution, home of Buzzies ... stress and anxiety. , “Buzzies change the way we interact with stress and ... , Since its launch date in December 2016, The TouchPoint Solution has sold more ...
(Date:3/23/2017)... ... , ... ?This conference will prominently feature 150+ Hospital and Health System Executive Speakers including: , ... , 43rd President of the United States of America: George W. Bush , ... Out of the Ring: Sugar Ray Leonard , JD, Chairperson, McGuireWoods LLP: Amber ...
(Date:3/23/2017)... ... 23, 2017 , ... It’s that time of year again! Time to think ... summer internships , which can be frustrating when they don’t even know how to ... a boutique public relations firm outside of Philadelphia, have offered these three tips to ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... skincare products, was awarded as winners of American Dreams & Good Housekeeping Seal ... hosted jointly by HSN and Good Housekeeping. , Steven Wang, MD ., ...
(Date:3/23/2017)... , ... March 23, 2017 , ... News Advisory/Interview Opportunity ... has helped score a major victory in Europe for public health and the environment ... , Based on rigorous scientific research and the overwhelming support of European citizens, the ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017  Cornerstone Pharmaceuticals, Inc., a ... milestone today.  Following successful End-of-Phase I (EOP1) ... and Drug Administration (FDA), the Company has ... path forward to conduct pivotal trials of ... acute myeloid leukemia (AML) and pancreatic cancer. ...
(Date:3/23/2017)... March 23, 2017 Piramal ... Limited, anuncia el nombramiento de Stuart E. ... plataforma de servicios integrados completa para su base ... cargo clave en el crecimiento y ejecución de ... responsable de impulsar todas las actividades de desarrollo ...
(Date:3/23/2017)... Merrimack Pharmaceuticals, Inc. (NASDAQ: MACK ) ... a Phase 1 study of MM-310 in solid tumors. ... novel taxane and targets the EphA2 receptor, a protein ... major tumor types, including prostate, ovarian, bladder, gastric, pancreatic ... study is an important step in evaluating MM-310,s safety ...
Breaking Medicine Technology: