Navigation Links
Body's 'Clock' Gene May Play Role in Depression
Date:11/18/2010

THURSDAY, Nov. 18 (HealthDay News) -- Depression may be linked to increased activity in the gene that regulates the body's 24-hour (circadian) clock, the results of a study suggest.

Researchers collected blood samples from 30 people with a history of depression and 30 people who had never been diagnosed with the disorder. The blood samples were analyzed to assess messenger RNA levels related to four circadian genes. Messenger RNA levels indicate gene activity.

Participants with a history of depression had a higher level of activity of the gene known as the Clock gene than those who had never had depression. Increased activity of the Clock gene suggests a problem with the 24-hour biological and behavioral cycle, which could affect sleep patterns and other physical functions governed by circadian rhythm, the researchers said.

"We know that there are a lot of insomnia symptoms in depression, especially early morning awakening," lead author Jean-Philippe Gouin, a graduate student in psychology at Ohio State University, said in a university news release.

"We can't say with this study that there is a direct relationship between this altered gene function and behavior, but the research suggests that over-expression of circadian genes might serve as a biomarker of vulnerability to depression," Gouin added.

The study was published in a recent issue of the Journal of Affective Disorders.

The findings suggest that people with depression who have increased Clock gene activity might get the most benefit from sleep-related treatments, such as light therapy or antidepressants that affect the hormone melatonin, which regulates sleep.

More information

The U.S. National Institute of Mental Health has more about depression.

-- Robert Preidt

SOURCE: Ohio State University, news release, Nov. 9, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. As Clocks Fall Back on Sunday, Think About Better Sleep
2. Temperature rhythms keep body clocks in sync, UT Southwestern researchers find
3. Ticking biological clock increases womens libido, new research shows
4. Turning back the cellular clock
5. Green Light Exposure Can Reset Body Clock
6. Excelltech's New iPhone Alarm Clock App Announces Time When Asked
7. Fish Oil Pills Turn Back The Clock On Aging
8. Biological clock could be a key to better health, longer life
9. Depression linked to HIV risk among South African young people, study shows
10. Social Class May Affect Outcome of Depression Treatment
11. Additional cardiac testing vital for patients with anxiety and depression
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Body's 'Clock' Gene May Play Role in Depression
(Date:1/17/2017)... ... January 17, 2017 , ... January is National Stalking Awareness Month (NSAM), now ... in the corners and commit the crime of stalking, a very real danger to many ... often overlooked factor in stalking and other crimes. , “Stalking: know it. Name it. Stop ...
(Date:1/17/2017)... ... January 17, 2017 , ... Gym Source, America’s leading retailer of premium ... South Dixie Hwy in Miami, FL. , “We are elated to be opening this ... in-store concept is designed to give clients a seamless and motivating shopping experience.” , ...
(Date:1/17/2017)... , ... January 17, 2017 , ... For breast cancer ... Symposium (SABCS) or those who desire a more intimate review and analysis of its ... – Bench to Bedside—is being offered by Imedex on February 4, 2017 in Chicago. ...
(Date:1/17/2017)... ... 17, 2017 , ... Healthful Balance announces the national release ... operated by Ed Stroup, was created to offer the highest quality vitamins and ... customer service. Healthful Balance products can be purchased online through their website, or ...
(Date:1/17/2017)... ... January 17, 2017 , ... Kevin Harrington (one of the original Sharks from ... campaigns regarding the topic of Beauty and Personal Care. , Everyone ... better way to commit to these changes than beginning with personal care and beauty ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... 18, 2017  Robust competition in the private ... on medicine prices, according to a new study ... is among the first to examine the share of ... pharmacy benefit managers (PBMs), health plans and other stakeholders ... is the first to show what happens when the ...
(Date:1/18/2017)... Chinese Food and Drug Administration CSL CureVac ... Food and Drug Administration FORT Fresenius Pharmaceuticals ... Glaxo Smith Klein GlaxoWellcome Global Influenza Programme ... Immune Targeting Systems Indian Association of Paediatrics ... Johnson & Johnson Krka Pharmaceuticals Medicago ...
(Date:1/17/2017)... , Jan. 17, 2017 North America ... GlobalData,s new report, "North America Insulin Delivery Market Outlook ... America Insulin Delivery market. The report provides value, in ... prices (USD) within market segments - Insulin Pens, Insulin ... The report also provides company shares and distribution shares ...
Breaking Medicine Technology: