Navigation Links
Blood vessel bends and branches put the brakes on statins
Date:7/9/2009

exposed to sluggish or disrupted blood flow.

Dr Mason, who led the team from the National Heart and Lung Institute, Imperial College London at Hammersmith Hospital, said: "Arteries don't clog up in a uniform way. Bends and branches of blood vessels - where blood flow is disrupted and can be sluggish - are much more prone to fatty plaques building-up and blocking the artery. What we've shown is that those regions of the arteries most likely to become diseased are the same regions that may not be benefiting maximally from statin treatment - a double whammy."

"We now hope to use these findings to identify a way to get the most out of statins, or to find other ways to switch on protective mechanisms in vulnerable areas of arteries."

Research suggests that the cells lining our arteries can sense 'shear stress' exerted by blood flowing past them, and that this affects their ability to keep the artery healthy. Straighter sections of arteries, with no branches, tend to have faster blood flow and are more protected from build-up of fatty plaques.

Professor Peter Weissberg, Medical Director of the BHF said "This research demonstrates how the physical forces inside blood vessels may influence the local action of drugs such as statins. The findings open avenues of investigation that could lead to greater health benefits of statins' being realised.

"Previous research has revealed that endothelial cells produce protective biological signals in parts of the artery where blood flow is fast and uniform and that this is lost in areas where blood flow is disrupted or non uniform, leading to build up of dangerous fatty deposits. This study shows that differing forces of blood flow may also cause the endothelial cells to be less responsive to a potentially protective antioxidant effect of statins.

"Research teams at Imperial - involving biologists and fluid engineers - are now taking these findings
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Pioneer of Digital Place-Based Media Joins World's Leading Blood Pressure and Health Kiosk Manufacturer
2. Cord Blood America Leases Las Vegas Building for Its Own Stem Cell Laboratory
3. Vegetable Amino Acid Lowers Blood Pressure
4. Intensive management can improve blood pressure in non-adherent hypertensive patients
5. Women's Health Expert Dr. Susan Lark Featured on Searchbloodsugar.com
6. Parents Guide to Cord Blood Foundation Introduces New Brochure During Cord Blood Awareness Month to Address Critical Education Gap
7. Stem Cell Industry Expert Praises, Encourages Continued Progress on Legislation to Promote Benefits of Cord Blood
8. CSC to Kick Off National Blood Drive Campaign July 8 at Global Headquarters in Virginia
9. Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels
10. Cord Blood Awareness Month: Understanding Still Low, Despite Medical Advancements
11. Newer Blood Tests May Not Improve Heart Risk Assessment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2015)... Kantar Health UK, a leading global ... Best Small Companies to Work For” list for 2015. This ... on the list, which measures employees’ levels of fulfilment, motivation ... Kantar Health UK, and we are delighted to be included ... Mark Hinton-Jones said. “The team is dedicated to putting clients ...
(Date:2/26/2015)... (PRWEB) February 26, 2015 Body Well Therapy, ... ten years of delivering high quality mobile massage ... and other regions across the United States. The company has ... a pivotal year as it sets its sights on additional ... office chair massage services. , “We’ve come a long way ...
(Date:2/26/2015)... 2015 The federal litigation established ... move forward in the U.S. District Court, Eastern ... to court records, the proceeding issued its eighth ... Xarelto Products Liability Litigation, No. 2592) , “The ... and procedures pertaining to the litigation’s Common Benefit ...
(Date:2/26/2015)... 26, 2015 It is no secret that a ... long shown that sleep improves the immune system, allows the body ... even helps a person lose weight. The message is clear, ... Time is crunched and people try to fit more and more ... heavily on the mind and caffeine and alcohol are simply part ...
(Date:2/26/2015)... Since its inception, the Master of ... at University of Western States (UWS) has incorporated innovative ... the two institutions forged a stronger alliance and signed ... between the two institutions, including integration of IFM’s novel ... training for HNFM faculty. As part of the agreement, ...
Breaking Medicine News(10 mins):Health News:Kantar Health UK Named One of The Sunday Times 100 Best Small Companies to Work For 2Health News:Body Well Therapy Celebrates 10 Years of Quality Mobile Massage Services 2Health News:Body Well Therapy Celebrates 10 Years of Quality Mobile Massage Services 3Health News:Federal Xarelto Lawsuits Progress, As Bernstein Liebhard LLP Comments on Issuance of Most Recent Pretrial Order 2Health News:Federal Xarelto Lawsuits Progress, As Bernstein Liebhard LLP Comments on Issuance of Most Recent Pretrial Order 3Health News:The Lodge at Woodloch Launches Rest+Well Blueprint- March 2015 2Health News:The Lodge at Woodloch Launches Rest+Well Blueprint- March 2015 3Health News:The Lodge at Woodloch Launches Rest+Well Blueprint- March 2015 4Health News:The Lodge at Woodloch Launches Rest+Well Blueprint- March 2015 5Health News:The Lodge at Woodloch Launches Rest+Well Blueprint- March 2015 6Health News:UWS and the Institute for Functional Medicine Sign Global Agreement 2
... WEDNESDAY, Feb. 1 (HealthDay News) -- To open a clogged ... metal stent to keep blood flowing or perform surgery. A ... arteries clear for at least two years and help prevent ... [heart] arteries, where re-blockage occurs about 20 percent of the ...
... , WEDNESDAY, Feb. 1 (HealthDay News) -- Sleep apnea, the ... already known to boost the risk of stroke. Now, a ... which there is tissue death in the brain without symptoms. ... loss before a stroke boosts the risk of the stroke ...
... -- Scientists may one day be able to read the minds ... suggests. In their report, published in the Jan. 31 ... California, Berkeley researchers describe how they have found a way to ... person hears in normal conversation. This ability to decode electrical ...
... www.genome.org ) publishes online and in print today ... gained form cutting-edge genomic and epigenomic analyses of ... novel biological insights gained from genomic analyses of ... genomic analyses of breast cancer genes, large scale ...
... , Baltimore, MD -- A new comparison of the ... blockages in the arteries of the neck concludes they ... after treatment with either surgery or a minimally invasive ... remained the same, approximately six percent. Results of the ...
... NBC Sports Group recently teamed up with the National Hockey ... of NHL Hockey"--an informative 10-part video series exploring the science ... students and teachers to use in the classroom, the videos ... standards, and are available to the public cost-free on ...
Cached Medicine News:Health News:Stenting, Surgery Appear Comparable for Opening Neck Artery 2Health News:Sleep Apnea May Be Tied to 'Silent' Strokes, Study Finds 2Health News:Sleep Apnea May Be Tied to 'Silent' Strokes, Study Finds 3Health News:Scientists Use Brain Waves to Eavesdrop on the Mind 2Health News:Genome Research publishes special issue: Cancer Genomics 2Health News:Genome Research publishes special issue: Cancer Genomics 3Health News:Genome Research publishes special issue: Cancer Genomics 4Health News:Genome Research publishes special issue: Cancer Genomics 5Health News:Genome Research publishes special issue: Cancer Genomics 6Health News:Genome Research publishes special issue: Cancer Genomics 7Health News:Stents and surgery for blocked neck arteries are neck-and-neck as lasting stroke prevention 2Health News:Stents and surgery for blocked neck arteries are neck-and-neck as lasting stroke prevention 3Health News:NBC News, NBC Sports and National Science Foundation launch 'Science of NHL Hockey' 2Health News:NBC News, NBC Sports and National Science Foundation launch 'Science of NHL Hockey' 3
(Date:2/26/2015)... 2015 Vectorious Medical Technologies, ... system for patients suffering from congestive heart failure ... $5 million financing round. Investors in the round ... by Yehuda Zisapel and Prof. Nava Zisapel ... Muntzer and others; and the U.S.-based Global Cardiovascular ...
(Date:2/26/2015)... Feb. 26, 2015  CSSi, ( www.CSSiEnroll.com ) ... clinical research industry, is pleased to announce the ... a Project Manager, adding significant value and expertise ... http://photos.prnewswire.com/prnh/20150225/177750 Karen is ... ability to successfully lead the navigation of the ...
(Date:2/26/2015)... Editor Note: For more ... Investor-Edge has initiated coverage on the following ... Teva Pharmaceutical Industries Ltd (NYSE: TEVA ), ... Inc. (NYSE: AGN ), and Depomed Inc. ... Johnson and Johnson can be accessed at http://get.Investor-Edge.com/pdf/?c=Johnson%20and%20Johnson&d=26-Feb-2015&s=JNJ ...
Breaking Medicine Technology:Vectorious Medical Technologies Completes $5M Raise 2CSSi's Continued Growth Brings Talented New Hire - Karen Welch Welcomed as Project Manager 2Updates on Pharma Stocks -- Johnson and Johnson, Teva Pharma Industries, Endo Intl., Allergan, and Depomed 2Updates on Pharma Stocks -- Johnson and Johnson, Teva Pharma Industries, Endo Intl., Allergan, and Depomed 3Updates on Pharma Stocks -- Johnson and Johnson, Teva Pharma Industries, Endo Intl., Allergan, and Depomed 4Updates on Pharma Stocks -- Johnson and Johnson, Teva Pharma Industries, Endo Intl., Allergan, and Depomed 5
... , NEW YORK, ... market research report is available in its catalogue. ... 2009 , http://www.reportlinker.com/p0164742/Global-Markets-for-Assisted-Reproductive-Devices-2009.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire ... U.S., 15 Countries in Europe and Japan. This ...
... Nov. 20 Cyberonics, Inc. (Nasdaq: CYBX ) today announced ... Chief Financial Officer, will present at the 21st Annual Piper Jaffray ... at 12:00 PM EST. The conference session and webcast will ... Piper Jaffray will host a webcast of the presentation live and ...
Cached Medicine Technology:Reportlinker Adds Global Markets for Assisted Reproductive Devices 2009 2Cyberonics to Present at 21st Annual Piper Jaffray Health Care Conference 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: