Navigation Links
Blood vessel bends and branches put the brakes on statins
Date:7/9/2009

exposed to sluggish or disrupted blood flow.

Dr Mason, who led the team from the National Heart and Lung Institute, Imperial College London at Hammersmith Hospital, said: "Arteries don't clog up in a uniform way. Bends and branches of blood vessels - where blood flow is disrupted and can be sluggish - are much more prone to fatty plaques building-up and blocking the artery. What we've shown is that those regions of the arteries most likely to become diseased are the same regions that may not be benefiting maximally from statin treatment - a double whammy."

"We now hope to use these findings to identify a way to get the most out of statins, or to find other ways to switch on protective mechanisms in vulnerable areas of arteries."

Research suggests that the cells lining our arteries can sense 'shear stress' exerted by blood flowing past them, and that this affects their ability to keep the artery healthy. Straighter sections of arteries, with no branches, tend to have faster blood flow and are more protected from build-up of fatty plaques.

Professor Peter Weissberg, Medical Director of the BHF said "This research demonstrates how the physical forces inside blood vessels may influence the local action of drugs such as statins. The findings open avenues of investigation that could lead to greater health benefits of statins' being realised.

"Previous research has revealed that endothelial cells produce protective biological signals in parts of the artery where blood flow is fast and uniform and that this is lost in areas where blood flow is disrupted or non uniform, leading to build up of dangerous fatty deposits. This study shows that differing forces of blood flow may also cause the endothelial cells to be less responsive to a potentially protective antioxidant effect of statins.

"Research teams at Imperial - involving biologists and fluid engineers - are now taking these findings
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Pioneer of Digital Place-Based Media Joins World's Leading Blood Pressure and Health Kiosk Manufacturer
2. Cord Blood America Leases Las Vegas Building for Its Own Stem Cell Laboratory
3. Vegetable Amino Acid Lowers Blood Pressure
4. Intensive management can improve blood pressure in non-adherent hypertensive patients
5. Women's Health Expert Dr. Susan Lark Featured on Searchbloodsugar.com
6. Parents Guide to Cord Blood Foundation Introduces New Brochure During Cord Blood Awareness Month to Address Critical Education Gap
7. Stem Cell Industry Expert Praises, Encourages Continued Progress on Legislation to Promote Benefits of Cord Blood
8. CSC to Kick Off National Blood Drive Campaign July 8 at Global Headquarters in Virginia
9. Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels
10. Cord Blood Awareness Month: Understanding Still Low, Despite Medical Advancements
11. Newer Blood Tests May Not Improve Heart Risk Assessment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... The report “Poxvirus Infections Pipeline Review ... development for Poxvirus Infections, complete with comparative analysis ... mechanism of action (MoA), route of administration (RoA) ... featured news and press releases. It also reviews ... Poxvirus Infections and special features on late-stage and ...
(Date:11/28/2014)... Recently, SWAccessControl.com, a renowned smartware manufacturer, has announced ... these high end products are offered at discounted rates, ... last from today to Dec 16, 2014. , The ... the promotion. We are proud of our new access ... information about our hottest items, we have listed some ...
(Date:11/28/2014)... York, NY (PRWEB) November 28, 2014 ... physical therapy techniques such as Dynamic Neuromuscular Stabilization, ... and gait/motion analysis. After moving to upgraded facilities ... and running clinic. Now, owner Dr. Lev Kalika ... performance and injury prevention lab in the country. ...
(Date:11/28/2014)... 28, 2014 (HealthDay News) -- People with diabetes face a ... help keep you healthy, an expert says. "With the ... deal with the events, the family you,ll be visiting and ... Association of Diabetes Educators, said in an association news release. ... be healthy." One idea is to make a healthy ...
(Date:11/28/2014)... Sunnyvale, CA (PRWEB) November 28, 2014 ... on December 2, 2014. This national movement was ... their communities by giving to local charities and causes. ... Thanksgiving Holiday, coincides with the kickoff of the holiday ... Friday is to shopping and Cyber Monday is to ...
Breaking Medicine News(10 mins):Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 2Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 3Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 4Health News:New Access Control Systems Now Offered At Low Prices By Smartware Manufacturer SWAccessControl.com 2Health News:New York Dynamic Neuromuscular Rehabilitation Opens Nation's Most Advanced Movement Performance and Injury Prevention Lab 2Health News:New York Dynamic Neuromuscular Rehabilitation Opens Nation's Most Advanced Movement Performance and Injury Prevention Lab 3Health News:Holiday Eating Tips for People With Diabetes 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 3
... Group, Inc. (SSI),announced today that Siemens Healthcare has ... through SSI,s ClickON(R), ClickON(R),s LinX,offering, and content partnership., ... Healthcare customers,to take advantage of a wide range ... Status, Secondary Billing, Audit Tracking and Note,Posting for ...
... had to become a "difficult patient" before she could get ... her health. , And once the diagnosis was made, she ... "difficult" before she could get the best treatment for scleroderma, ... is a major element. , Mayer, a research assistant professor ...
... PALM BEACH, Fla., Sept 10 If a ... bag of chips or a quart of ice ... emotional eating, which can,now be helped with The ... ), the first vegan, gluten-free vitamin with human,clinical ...
... is a unique online community for people who support affordable health ... ... Columbus, OH (PRWEB) September 10, 2008 -- While politicians dispense their ... are invited to do the same online. The common place to ...
... launches a unique, national weight and stress management program based upon ... ... (PRWEB) September 10, 2008 -- With high gasoline prices, depressed real ... Americans are skyrocketing. For those that attempt to eat their stress ...
... personalized service educates clients about Medicare; identifies best options and ... ... Belleville, Ill. (Vocus) September 10, 2008 ... the services it offers to individuals with disabilities with the ...
Cached Medicine News:Health News:SSI Announces Agreement with Siemens Healthcare 2Health News:Survival instincts propel 'difficult patient' to insist on quality care 2Health News:Survival instincts propel 'difficult patient' to insist on quality care 3Health News:Stress-Related and Emotional Eating Can Be Curbed With the Vitamin Code(TM) Perfect Weight Formula 2Health News:Stress-Related and Emotional Eating Can Be Curbed With the Vitamin Code(TM) Perfect Weight Formula 3Health News:Social Network For Affordable Health Care Supporters Stimulates A New Level of Interactivity and Dialogue 2Health News:Are You A Stress Eater? Revolutionary Program Reduces Overall Stress and Stress Eating Tendencies 2Health News:Are You A Stress Eater? Revolutionary Program Reduces Overall Stress and Stress Eating Tendencies 3Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 2Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 3Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 4Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 5
(Date:11/28/2014)... Nov. 28, 2014  Valeant Pharmaceuticals International, Inc. ... announced that its wholly owned subsidiary, Valeant Pharmaceuticals ... of its outstanding 6.875% Senior Notes due 2018, ... on December 29, 2014 and has mailed an ... the redemption, approximately US$500 million aggregate principal amount ...
(Date:11/28/2014)... , Nov. 28, 2014 /CNW Telbec/ - Ergoresearch Ltd ... appointment of Mrs. Dominique Boudreau who will ... team. Mrs. Dominique Boudreau was acting as ... occupied similar duties for more than seven years for ... in January 2013.  Mrs. Boudreau replaces Mr. Greco who ...
(Date:11/28/2014)... Aratana Therapeutics, Inc. (NASDAQ: PETX ), ... acquisition, development and commercialization of innovative biopharmaceutical products for ... it will present at the 26 th Annual ... 2014, at the New York Palace Hotel in ... St. Peter , M.D., President and Chief Executive Officer, ...
Breaking Medicine Technology:Valeant Announces Redemption of US$445.0 Million Aggregate Principal Amount of its Outstanding 6.875% Senior Notes due 2018 2Ergoresearch announces the appointment of its new Vice Président Finance 2Ergoresearch announces the appointment of its new Vice Président Finance 3Aratana Therapeutics to Present at the 26th Annual Piper Jaffray Healthcare Conference 2
... Measuring the body temperatures of newborns with temporal artery ... by axillary (under arm) thermometry, the clinically recommended method ... to a new study reported in Advances in ... first published clinical analysis evaluating the accuracy of temporal ...
... 18, 2011 BB&T Capital Markets served as the ... Comfort, the leading developer, manufacturer and marketer of therapeutic ... sale to DJO Global, an international provider of medical ... management based in Vista, Calif. Dr. Comfort generated net ...
Cached Medicine Technology:Study Finds Exergen Temporal Artery Thermometry Accurate on Newborns 2Study Finds Exergen Temporal Artery Thermometry Accurate on Newborns 3BB&T Advises Dr. Comfort on Its Sale to DJO Global in Transaction Valued at $254.6 Million 2
... , ... event is to use an ... environment. But will the device be durable enough? Can you depend, ... its signal quality? Will the battery last? Is it comfortable, ...
... new features and state-of-the ... innovation, the SuperStim brain ... stimulation up to 30 ... and transcranial stimulation up ...
... high-volume analyzer that builds upon the field-proven ... and the latest Olympus technological advances. The ... with up to 147 on-board chemistries and ... Choose from Olympus 122 test menu, including ...
... The AU640 e is ... mid-sized to large laboratories and hospitals. ... the AU640es field-proven reliability and Olympus ... chemistries, urine chemistry, specific proteins, esoteric ...
Medicine Products: