Navigation Links
Blood test for brain injuries gains momentum
Date:3/31/2009

brain. The time between injury and irreversible brain swelling is short and many drug studies have failed to find a therapy that leverages this time frame and works as designed.

Before the S-100B blood test, the best way to know if the BBB was open was to perform an invasive procedure called a ventriculostomy. (Doctors insert a catheter through the skull and into the brain, withdrawal fluid, and compare the concentration of albumin protein in the cerebrospinal fluid to the concentration in the blood.)

In a pilot study of 20 patients, however, Blyth found that serum S-100B concentrations could accurately predict the function of the blood-brain barrier 12 hours after injury, eliminating the need for the invasive procedure.

The study compared levels of S-100B proteins to the CSF-serum albumin quotient (Qa), the gold standard measurement signaling a brain injury. Researchers compared nine people with a known severe head injury, to 11 people who suffered from non-traumatic headaches.

Blyth and Bazarian believe the research may impact future drug studies. "The disability and death rates from brain injuries have not improved much in the past 20 years," Blyth said. "Many clinical trials for new medications have failed, probably because it was difficult to know if the blood-brain barrier was open and the drugs were reaching its target. Our study shows that any diagnostic test for brain injury should incorporate a way to measure the status of the blood-brain barrier into its design."


'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Specific antagonism lowers blood pressure
2. Restricting Blood Flow May Help Heart Bypass Patients
3. FDA Updates Prescription Guidelines for Blood Thinner
4. Doctors Often Miss High Blood Pressure in Kids
5. Back to School Means Return of School Blood Drives
6. Blood-flow detector software show promise in preventing brain damage
7. FDA Approves New Roche West Nile Virus Blood Screening Test
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Laser blasts viruses in blood
10. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
11. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... 29, 2014 After having a double ... had to have breast reconstruction. She found that the ... she decided that there needed to be a solution. ... a woman or man who needs or wants breast ... promotes confidence and peace of mind. Producible in design ...
(Date:8/29/2014)... 29, 2014 University of Western States ... professionals, announced that Daniel Redwood, DC, director of the ... of the Year,” by the Missouri State Chiropractors Association ... 21. , Patrick Montgomery, DC, president of the MSCA, ... the Missouri House Task Force for Medicaid Reform, in ...
(Date:8/29/2014)... Aug. 29, 2014 (HealthDay News) -- The West African Ebola ... Health Organization announcing an estimated 500 new cases this week ... of the new cases arose in Liberia, the U.N. health ... rose sharply, the Associated Press reported. "There ... control," according to the WHO report. "The situation is worsening ...
(Date:8/29/2014)... August 29, 2014 Sansego ... videos, an interactive online community, and a range of ... beginners all the way to professional athletes. Crowie has ... have been with him throughout the majority of his ... everyone in the triathlon public. , Sansego provides the ...
(Date:8/29/2014)... ReputationChief.Com, a well-established online reputation management firm, has ... service has been launched to help individuals and organizations ... them. , In order to make sure that the ... to its clients, ReputationChief.Com has designed the service after ... , As per the indications from the company management, ...
Breaking Medicine News(10 mins):Health News:University of Western States Director of Human Nutrition and Functional Medicine Daniel Redwood, DC, named Missouri Educator of the Year by MSCA 2Health News:Biggest Ever Weekly Rise in Ebola Cases, U.N. Agency Says 2Health News:Biggest Ever Weekly Rise in Ebola Cases, U.N. Agency Says 3Health News:5 x World Champion Triathlete, Craig “Crowie” Alexander, Launches Online Triathlon Coaching Company – Sansego 2Health News:5 x World Champion Triathlete, Craig “Crowie” Alexander, Launches Online Triathlon Coaching Company – Sansego 3Health News:ReputationChief.Com Announces a New Service ‘Remove Bad Reviews’ 2
... issue of the online journal Sexuality Research and ... reveal that abstinence-only-until-marriage sex education programs fail to change ... and violate human rights principles. Edited by John S. ... Department of Family and Population Health and Leslie M. ...
... Prestigious Award for Strong Market Share Growth, Product Innovation, ... ... Scottsdale, Ariz (PRWEB) September ... Management Solutions], Inc., a leading global security management company, ...
... holds that when it comes to aggression, boys hit ... exclude others, a type of aggression that,s called indirect, ... 150 studies of aggression in children and adolescents has ... likely to engage in physical aggression, girls and boys ...
... French . Montreal, September 16, 2008 ... than the birds and bees with their parents they ... out with older boys. A new study by researchers from ... Tufts University, published in the journal Child Development , ...
... flu? Not yet. But a new study offers new ... significant help. The three-year study showed that trial participants ... get a "Jackson" cold or flu. The very sensitive ... judging clinical symptoms, which include coughing, sneezing, runny noses ...
... AMDL, Inc. (Amex:,ADL), a vertically integrated pharmaceutical company with ... is reaffirming guidance for Q3 and,FY2008. Additionally, the Company ... to the heightened activity in its common stock,on the ... it is the Company,s normal policy to not comment ...
Cached Medicine News:Health News:Accuracy, efficacy and ethics of abstinence-only programs questioned by public health experts 2Health News:Accuracy, efficacy and ethics of abstinence-only programs questioned by public health experts 3Health News:Accuracy, efficacy and ethics of abstinence-only programs questioned by public health experts 4Health News:Lumension Security Receives Frost & Sullivan 2008 Global Market Penetration Leadership Award 2Health News:Lumension Security Receives Frost & Sullivan 2008 Global Market Penetration Leadership Award 3Health News:Lumension Security Receives Frost & Sullivan 2008 Global Market Penetration Leadership Award 4Health News:Lumension Security Receives Frost & Sullivan 2008 Global Market Penetration Leadership Award 5Health News:Move over mean girls -- boys can be socially aggressive, too 2Health News:Troubled girls from poor neighborhoods more likely to have sex in early adolescence 2Health News:Troubled girls from poor neighborhoods more likely to have sex in early adolescence 3Health News:Colds and flu cut by one-third in study of Canada's top cold fighter in vaccinated seniors 2Health News:Colds and flu cut by one-third in study of Canada's top cold fighter in vaccinated seniors 3Health News:AMDL Reaffirms 2008 Guidance and Provides Additional Information 2Health News:AMDL Reaffirms 2008 Guidance and Provides Additional Information 3
(Date:8/29/2014)... 29, 2014 Research and Markets ... Sclerosis Drugs Market 2014-2018" report to their offering. ... medical condition that results in demyelination, axonal transection, and ... abnormal response by the immune system, which targets neurons ... potentially debilitating disease in which the damage of the ...
(Date:8/29/2014)... 29, 2014 Pixcelldata, the innovative ... has announced a major new deal with Dutch based ... pathology expert, Dr. Marius Nap . ... European Congress of Pathology which is taking placing between ... London where Pixcelldata will demonstrate ...
(Date:8/28/2014)... 28, 2014  Rigrodsky & Long, P.A.: , ... (NYSE: LCI )? , Did you purchase your ... July 16, 2014, inclusive? , Did you lose money ... you want to discuss your rights? ... Attorney, Timothy J. MacFall , announces that a complaint has ...
Breaking Medicine Technology:Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 3Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 3
... Systems Ltd. (Nasdaq: DHRM ) ("Dehaier" or ... marketing and sale of medical devices and homecare medical ... Weibing Yang as and Dr. Genhui Chen directors of ... fills the vacancy resulting from the resignation of Ms. ...
...  Researchers have published the largest single patient population ... patients with retrievable inferior vena cava (IVC) filters—devices ... the lungs. This study, which is important for ... existing guidelines developed by the Society of Interventional ...
Cached Medicine Technology:Dehaier Medical Announces Changes to Board of Directors 2Dehaier Medical Announces Changes to Board of Directors 3IVC Filters: Society of Interventional Radiology Leads in Patient Care, Safety, Research 2IVC Filters: Society of Interventional Radiology Leads in Patient Care, Safety, Research 3IVC Filters: Society of Interventional Radiology Leads in Patient Care, Safety, Research 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: