Navigation Links
Blood test can predict rheumatoid arthritis before symptoms arise
Date:1/27/2010

ed, the team conducted a nested casecontrol study within the Medical Biobank of Northern Sweden. Blood samples were analyzed from 86 individuals before the appearance of symptoms of RA (pre-patients), from 69 of the pre-patients after the onset of RA, and from 256 matched control subjects (1:3 ratio). A consecutive time-dependent involvement of the immune system in disease development and progression was evaluated. The plasma levels of 30 cytokines, related factors, and chemokines were measured using a multiplex system. Individuals in whom RA subsequently developed were discriminated from control subjects mainly by the presence of Th1 cell-, Th2 cell-, and Treg cellrelated cytokines, while chemokines, stromal cellderived cytokines, and angiogenic-related markers separated patients after the development of RA from individuals before the onset of RA.

"We observed a clear relationship between cytokines related not only to Th1, Th2, and Treg cells but also to Th17 and the presence of anti-CCP antibodies, thereby supporting the concept that the immune system was already stimulated and disease was developing toward RA," explains Dr. Rantap-Dahlqvist. Researchers found that blood samples obtained from individuals had elevated concentrations of proinflammatory cytokines, cytokine-related factors, and chemokines, indicating immune system activation prior to any symptoms of joint involvement. "Our findings present an opportunity for better predicting the risk of developing RA and possibly preventing disease progression," concluded Dr. Rantap-Dahlqvist.


'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Aging of Blood Stem Cells May Be Reversible
2. Fat tissue may be a source of valuable blood stem cells, study says
3. Tight Blood Sugar Control May Raise Risk of Death
4. For Lower Blood Pressure, Low-Carb Diet May Be Best
5. Newborns of Smokers Have Abnormal Blood Pressure
6. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
7. Blood Test Spots Colon Cancer, Polyps
8. First successful use of expanded umbilical-cord blood units to treat leukemia
9. CBS News Helps Red Cross Transport Blood into Haiti
10. Bioengineered Skin Grafts Control Blood Pressure in Mice
11. Raising kids may lower blood pressure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... Request A Test , a leading national provider of direct ... drug testing in September 2014. To take advantage ... DRUG10 when placing their order. Request A Test offers a ... testing is typically done in panels which screen for multiple types ... include the 5 Panel Urine Screening and 10 ...
(Date:9/2/2014)... support for marijuana legalization in the U.S. has led ... other substances, such as alcohol. In January, President Obama ... is more dangerous than alcohol. Despite the recent shift ... compared to alcohol use are not well understood. ... Associated with Drug Use among US High School Seniors: ...
(Date:9/2/2014)... Tuesday 2 September 2014: A simple awareness campaign in ... according to research presented at ESC Congress today by ... "Atrial fibrillation (AF) is the most common cardiac arrhythmia. ... three-fold and the risk of stroke risk by five-fold. ... of 4 cases. However, AF is often overlooked and ...
(Date:9/2/2014)... September 02, 2014 Aeroflow Healthcare, an ... the Southeast, announced the opening of its new office ... address is: 310 Business Parkway, Suite D, Greer, SC ... service patients with a more convenient location in the ... Aeroflow Healthcare and the physicians, hospitals and patients we ...
(Date:9/2/2014)... September 2014 – The days when skin care ... men shave daily – and commit common mistakes that can ... isn’t inevitable, according to Joshua Fox, MD, medical ... skin care was something in which only women seemed interested. ... all ages who realize that their fathers’ bare-bones routine of ...
Breaking Medicine News(10 mins):Health News:Request A Test Offers 10% Off Drug Testing in September 2014 2Health News:Request A Test Offers 10% Off Drug Testing in September 2014 3Health News:NYU study compares consequences of teen alcohol and marijuana use 2Health News:NYU study compares consequences of teen alcohol and marijuana use 3Health News:Simple awareness campaign in general practice identifies new cases of AF 2Health News:Aeroflow Healthcare Opens Office In Greer, SC To Service Greenville & Spartanburg Patients 2Health News:Rough Isn’t Rugged in Men’s Skin: Dermatology specialist Dr. Joshua Fox with Advanced Dermatology PC offers tips on easy skin maintenance for men 2Health News:Rough Isn’t Rugged in Men’s Skin: Dermatology specialist Dr. Joshua Fox with Advanced Dermatology PC offers tips on easy skin maintenance for men 3
... children are not checked properly for their safety ... University Medical Center researchers. // The drugs that ... and sedatives. ,The researchers analyzed drugs ... "pediatric exclusivity," through which the Food and Drug ...
... growing number of HIV infected individuals, India plans to ask ... the country to // teach others about safe sex and ... weavers, or agricultural laborers or just be hanging around the ... National Aids Control Organization "But the point is the distribution ...
... being reported from Rajasthan, officials say. According to the health ... with symptoms of dengue. Last month the number was 15. ... have been reported from Dholpur, Karauli and Sawai Madhopur districts. ... state, the government has stepped up measures to control the ...
... factors that are linked with an increased risk for ... long-QT syndrome (an abnormality of the electrical conducting system ... the ECG), according to a study. ,Risk factors ... an episode of cardiac arrest is reversed, such as ...
... new study commissioned by the World Health Organization has suggested ... treatments may work against SARS// in the event of the ... that was conducted during and after the 2003 outbreak that ... of any treatments employed that had any effect on the ...
... obstructive pulmonary disease (COPD) who use inhaled corticosteroids ... according to a new study published in the ... the American College of Chest Physicians (ACCP). New ... within 30 days of hospital discharge had a ...
Cached Medicine News:Health News:Doctors Unaware If Pediatric Dosages Are Safe 2Health News:Doctors Unaware If Pediatric Dosages Are Safe 3Health News:Factors Associated With Increased Risk of Cardiac Arrest For Adolescents 2Health News:Treatment of SARS Still a Mystery 2Health News:Inhaled Corticosteroids Reduce Death in Patients with COPD 2
(Date:9/2/2014)... SAN ANTONIO , Sept. 2, 2014 /PRNewswire/ ... private medical technology company focused on innovating lifesaving ... announced the appointment of Dr. Gabriele Niederauer ... President and CEO. Following the recent closure of ... CE Mark for the Surfacer™ Inside-Out Access Catheter ...
(Date:9/2/2014)... , Sept. 2, 2014   Veracyte, Inc. (Nasdaq: ... Anderson , president and chief executive officer, will present in ... Healthcare Unplugged Conference 2014 on Monday, September 8, 2014 at ... The live audio webcast and subsequent replay may ... Please connect to the website at least 15 minutes prior ...
(Date:9/2/2014)... 2, 2014 Isis Pharmaceuticals, Inc. (NASDAQ: ... drugs in its lipid franchise were highlighted in four ... Congress in Barcelona Spain . Isis ... to provide effective and safe therapeutic options to treat ... one commercialized drug and several other drugs in clinical ...
Breaking Medicine Technology:Bluegrass Vascular Technologies Names Dr. Gabriele Niederauer President And CEO 2Veracyte to Present at the Morgan Stanley Global Healthcare Unplugged Conference 2014 2Drugs from Isis' Lipid Franchise Highlighted at European Society of Cardiology Congress 2014 2Drugs from Isis' Lipid Franchise Highlighted at European Society of Cardiology Congress 2014 3Drugs from Isis' Lipid Franchise Highlighted at European Society of Cardiology Congress 2014 4Drugs from Isis' Lipid Franchise Highlighted at European Society of Cardiology Congress 2014 5
... Centuries of German Craftsmanship ... instrumentation in the world. Ocutek ... you! Only holders of the ... and eight-year apprenticeship, are qualified ...
... Centuries of German Craftsmanship ... instrumentation in the world. Ocutek ... you! Only holders of the ... and eight-year apprenticeship, are qualified ...
... German Craftsmanship have produced the ... world. Ocutek now makes them ... of the coveted Meisterbrief certificate, ... are qualified to become Ocutek ...
... of German Craftsmanship have produced ... the world. Ocutek now makes ... holders of the coveted Meisterbrief ... apprenticeship, are qualified to become ...
Medicine Products: