Navigation Links
Blood test accurately predicts death from prostate cancer up to 25 years in advance
Date:9/14/2010

NEW YORK, September 14, 2010 A blood test at the age of 60 can accurately predict the risk that a man will die from prostate cancer within the next 25 years, according to researchers at Memorial Sloan-Kettering Cancer Center, in New York, and Lund University, in Sweden. The findings, published today online in the British Medical Journal, could have important implications for determining which men should be screened after the age of 60 and which may not benefit substantially from continued prostate cancer screening.

The study analyzed blood samples from 1,167 men born in 1921 that were collected between 1981 and 1982 as part of the Malm Preventive Project in Sweden. All men were carefully followed until they had reached age 85 or had died. After studying various biomarkers, the researchers found that the PSA level was a highly accurate predictor of long-term risk. PSA testing has been recommended for the early detection of prostate cancer for many years; however this new data suggests a baseline PSA could determine who should and should not continue to be screened for prostate cancer.

"We were hoping to find a novel marker," said lead researchers Andrew Vickers, PhD and Hans Lilja, MD PhD. "What we found instead was a new way of using an old test."

According to the study, 126 men were diagnosed with prostate cancer, and of those, 90 percent of deaths occurred in men in the top 25 percent of PSA levels at age 60. The researchers concluded that men with a PSA level above 2 ng/ml at age 60 should be considered at increased risk of aggressive prostate cancer and should continue to be screened regularly.

Men with a PSA level below 1 ng / ml had a 0.2 percent chance of death from prostate cancer. The researchers concluded that men with PSA levels in this range, which is about half of all men, should be considered at low risk of prostate cancer death and may not need to be screened in the future. The study also indicated that some men found to be at low risk may actually have prostate cancer; however it is not likely to cause symptoms or shorten their life by the age of 85.

"This is a key finding," said Dr. Vickers. "We know that screening detects many prostate cancers that are not harmful, leading to anxiety and unnecessary treatment. It is our ability to determine the risk of the really aggressive cancers that makes this approach of such great potential value."


'/>"/>

Contact: Kathleen Harrison
harrisok@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Related medicine news :

1. Lack of trust in hospitals a major deterrent for blood donation among African-Americans
2. Improvement in prediction of blood clots in cancer patients
3. Overactive Blood Platelets May Play Role in Lupus
4. McMaster study contradicts reports of problems with blood-thinner
5. Even modest weight gain can harm blood vessels, Mayo researchers find
6. Novel role: EZH2 boosts creation of ovarian cancer blood vessels
7. Scientists map epigenetic changes during blood cell differentiation
8. Selected cells from blood or bone marrow may provide a route to healing blood vessels
9. Just a Little Belly Fat Can Damage Blood Vessels
10. Caltech biologists discover microRNAs that control function of blood stem cells
11. MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2017)... ... 2017 , ... CareSet Labs released the Root NPI Graph today at the ... greatly improved version of the Doctor Referral teaming dataset commonly available from Medicare. , ... called the the “Doctor Referral Dataset” as released by Medicare and “DocGraph” as released ...
(Date:6/24/2017)... , ... June 24, 2017 , ... ... Erie, PA at the Sheraton Erie Bayfront and Erie Convention Center on June ... medicine experience, exhibits, a student quiz bowl, award and scholarship presentations, and professional ...
(Date:6/23/2017)... Providence, RI (PRWEB) , ... June 23, 2017 ... ... Community Care Network today announced the launch of Care Management Alerts and Dashboards, ... for 140,000 patients throughout Rhode Island. , RIQI’s Care Management Alerts and Dashboards ...
(Date:6/23/2017)... ... , ... Studies show evidence that carotenoids and antioxidants derived either from the ... patients. , But how often do ophthalmologists and optometrists in Sweden recommend the use ... or with early symptoms of AMD? A study published recently in Dove ...
(Date:6/23/2017)... ... June 23, 2017 , ... Everybody has their own personal ... prefer to read it, and some people don't like it at all. FindaTopDoc took ... they found: , Erotic literature can give readers a taste of their deepest, darkest ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 7, 2017  Novavax, Inc., (Nasdaq: NVAX ) ... 2 trials of its RSV F protein recombinant nanoparticle vaccine ... have been published in the journal Vaccine ... in prior scientific conferences). The Company previously announced top ... is developing the RSV F Vaccine with the goal of ...
(Date:6/2/2017)... , June 2, 2017  NxStage Medical, Inc. (Nasdaq:  NXTM), a ... today announced new findings demonstrating positive biochemical outcomes related ... System One™. The data will be presented at the ... Madrid, Spain . The ... Home Dialysis Network in Europe ...
(Date:5/29/2017)... -- Cellect Biotechnology Ltd. (NASDAQ: APOP ; TASE: APOP), ... selection of stem cells, today provided a corporate update ... March 31 st , 2017. "We ... quarter of 2017," said Dr. Shai Yarkoni, Chief Executive ... of the first blood cancer patient in the recently ...
Breaking Medicine Technology: