Navigation Links
Blood test accurately distinguishes depressed patients from healthy controls
Date:2/1/2012

, and the interaction between brain structures involved with stress response and other key functions. Those measurements are combined using a specific formula to produce a figure called the MDDScore a number from 1 to 100 indicating the percentage likelihood that the individual has major depression. In clinical use the MDDScore would range from 1 to 10.

The initial pilot phase of the study enrolled 36 adults who had been diagnosed with major depression at the MGH, Vanderbilt University or Cambridge Health Alliance in Cambridge, Mass., along with 43 control participants from St. Elizabeth's Hospital in Brighton, Mass. MDDScores for 33 of the 36 patients indicated the presence of depression, while only 8 of the 43 controls had a positive test result. The average score for patients was 85, while the average for controls was 33. A second replication phase enrolled an additional 34 patients from the MGH and Vanderbilt, 31 of whom had a positive MDDScore result. Combining both groups indicated that the test could accurately diagnose major depression with a sensitivity of about 90 percent and a specificity of 80 percent.

"It can be difficult to convince patients of the need for treatment based on the sort of questionnaire now used to rank their reported symptoms," says Bilello. "We expect that the biological basis of this test may provide patients with insight into their depression as a treatable disease rather than a source of self-doubt and stigma. As we accumulate additional data on the MDDScore and perform further studies, we hope it will be useful for predicting treatment response and helping to select the best therapies."

Papakostas adds, "Determining the true utility of this test will require following this small research study with larger trials in clinical settings. But these results are already providing us with intriguing new hints on how powerfully factors such as inflammation which we are learning has a major role in m
'/>"/>

Contact: Kristen Stanton
kstanton3@partners.org
617-643-3907
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. 2-arm blood pressure check indicator for risk from heart disease or death
2. Lifestyle Counseling Helps Diabetes Patients Control Blood Sugar
3. Could Alzheimers disease be diagnosed with a simple blood test?
4. Lead blood levels may increase smokers risk for kidney cancer
5. Repeat Scans Urged for Head Injury When Blood Thinners Involved
6. Experimental Blood Thinner Given Before Surgery Shows Benefit
7. Upper Normal Blood Pressure Linked to Heart Risk in Men
8. Joint Replacement Patients Face Blood Clot Risk in Hospital
9. Canadas first renal denervation procedure to reduce high blood pressure performed today
10. New Blood Thinner Linked to Higher Heart Attack Risk
11. Short Delay in Treating Blood Pressure Safe for Diabetics: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... Lake Worth, FL (PRWEB) August 28, 2014 ... promote National Recovery Month throughout September. This month ... of addiction treatment and mental health services. Along ... Millennium Treatment Group is helping to spread the ... Month began in 1989, honoring the work of ...
(Date:8/28/2014)... American adults who are beginning to research ... now have a simpler way to connect with companies ... year, some of the best life insurance rates available ... The promoted plans that included price data revealed to ... policies. The term, guaranteed and modified plans that might ...
(Date:8/28/2014)... 2014 ABC television stars will join ... Show of Strength Telethon airing Sunday, Aug. 31, 9/8c ... raise funds and awareness to help save and improve ... disease. , Viewers tuning into the 2014 telethon to ... and introductions from some of the network’s leading stars, ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 ... announced today a regional partnership designed to advance ... planning for competitive young athletes, scholastic athletes and ... partnership’s Strong Body & Mind Initiative will offer ... both the physical and mental dynamics involved in ...
(Date:8/28/2014)... 28, 2014 Gurnick Academy of Medical ... program is re-accredited for the 5 years of the ... Technologists (ARMRIT). , “We are very proud to ... our program to make sure we provide the best ... interest in MRI field nowadays and I look forward ...
Breaking Medicine News(10 mins):Health News:Millennium Treatment Group Celebrates National Recovery Month 2Health News:Best Life Insurance Rates for 2014 Now Promoted at Insurer Website 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 3Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 4Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 2Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 3Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 4Health News:Gurnick Academy’s MRI Program Is Re-Accredited by ARMRIT for the 5 Years 2
... Medicine have just developed an advanced imaging technique to ... white blood cells. Microdomains are restricted areas on the ... molecules accumulate during cell activation. Using digital multi-channel videomicroscopy, ... and their forming microdomains in the vascular system in ...
... national guidelines recommend that, if managed, may have prevented ... in the issue of Neurology, the scientific journal of ... study of 1,040 people hospitalized for stroke or transient ... higher than recommended by national guidelines. TIA happens when ...
... But they are still just as sensitive as anyone else. Ignoring ... so//. ,Members of the "stronger sex" often expect a ... Many only consult a doctor when it's too late and could ... ,German men have a life expectancy of around 76 years, compared ...
... who smoke are increasingly at the risk of becoming ... turn into active TB disease//, according to an analysis ... Medicine. ,About one-third of the world’s population is ... the organism is usually rendered inactive by the immune ...
... molecular mechanisms behind most of the body’s sensing capabilities. Vision, ... pigment molecule that is extremely sensitive to light. It is ... decoded by the brain into visual information. But how the ... temperature has remained a mystery. ,“For a ...
... drug Vandetanib, marketed by London company AstraZeneca PLC// has begun. ... of lung cancer in whom the first-line treatment has failed. ... , The patients who have a recorded a case ... be given the once-daily drug Vandetanib in addition to pemetrexed, ...
Cached Medicine News:Health News:New Imaging Technique Tracks Traffic Patterns of White Blood Cells 2Health News:Cholesterol in Stroke Patients Exceeds National Guidelines 2Health News:Men Not as Tough as They Seem 2Health News:Susceptibility to TB is High Among the Smokers 2Health News:Researchers Discover Key to Body’s Ability to Detect Subtle Temperature Change 2Health News:Researchers Discover Key to Body’s Ability to Detect Subtle Temperature Change 3
(Date:8/28/2014)... /PRNewswire-iReach/ -- Academy Leadership, an elite leadership training firm ... a case study highlighting one manager,s experience ... In September and October 2014, Academy Leadership affiliates are ... , Indianapolis , Salt Lake City , ... http://photos.prnewswire.com/prnh/20140828/140814 Leadership training for managers ...
(Date:8/28/2014)... , Aug. 28, 2014 Nonin Medical, ... leader in noninvasive medical monitoring, today announced that the ... Model 3231 OEM/eHealth finger pulse oximeter for use in ... pulse oximeter plugs into a telemedicine hub or kiosk ... pulse rate in pediatric to adult patients. The Model ...
(Date:8/28/2014)... According to a new market ... Market (Tags, Readers, Middleware, Printers and Cabinets) - Global ... - 2020" the global radiofrequency identification (RFID) market was ... expected to grow at a CAGR of 13.9% from ... USD 5.3 billion in 2020. Browse the ...
Breaking Medicine Technology:Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 2Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 3Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 4Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 5Nonin Medical Announces FDA Clearance of Nonin Model 3231 USB Pulse Oximeter 2Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 2Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 3Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 4Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 5
... , CARSON CITY, Nev. , ... the launch of www.BionicCigs.com , the premiere website for ... this exciting new product that helps smokers wishing to quit and ... electronic cigarette market is estimated to be a $100 Million ...
... , Feb. 2 Advanced Health Media, LLC ... compliance technology and services, announced it has acquired substantially all ... Piscataway, NJ -based provider of marketing services for the pharmaceutical ... will remain at AHM,s Bridgewater, N.J. office. Terms ...
Cached Medicine Technology:Rapid Fire Marketing Enters Electronic Cigarette Market 2Advanced Health Media Acquires Advogent 2Advanced Health Media Acquires Advogent 3
Stainless steel. Lamp is in fiberoptic handle. Green color coding. The blade includes a port that permits delivery of oxygen or other gas mixtures during intubation....
... of the vocal cords in even the most ... like a standard laryngoscope, Viewmax® does not require ... its ability to allow intubation whether you are ... airway. It has a patented lens system that ...
... Stainless steel. Lamp supplied with ... operate on any standard/conventional handle allowing ... illumination without the potential confusion from ... blades offer an easy and cost ...
... The FR-120F, Fujinon's new fiberoptic Naso-Pharyngo-Laryngoscope provides ... patient comfort. The latest in Fujinon ... increased light guide, and a wide 90 ... impressive 3.3mm distal tip diameter. In ...
Medicine Products: