Navigation Links
Blood-pressure-lowering drug after stroke aids recovery, study finds
Date:10/21/2011

Athens, Ga. A commonly prescribed blood pressure-lowering medication appears to kick start recovery in the unaffected brain hemisphere after a stroke by boosting blood vessel growth, a new University of Georgia study has found.

The discovery, based on a study using rats and published recently in the online journal PLoS ONE, occurred only because the team, led by Susan Fagan, professor of clinical and administrative pharmacy at the UGA College of Pharmacy, struck a new path in stroke research by examining the healthy side of brain after the stroke occurred.

"I'm very excited because I think we can harness the restorative properties of the contralesional hemispherethe other side of the brainwith drug therapies," Fagan said. "When most researchers study stroke they compare the animal's side of the brain that's damaged to the opposite side, assuming that that side is normal or not affected."

For the study, Fagan and her team induced strokes in two groups of male Wistar rats by blocking a major artery in the brain. A third group of placebo, or sham, animals did not experience strokes so that scientists could compare healthy brain hemispheres across all groups. One group received a single dose of saline solution; the other received a dose of the blood pressure drug candesartan. The placebo group received no treatment.

Animals treated with candesartan displayed higher levels of growth factors that aid with the formation of new blood vessels in the brain, a result that confirmed that of earlier studies from the lab. However, the study revealed a previously unobserved phenomenon: Different types of growth factors dominated different hemispheres in the brain, which suggests that candesartan could have healing properties beyond the area of damage.

Doctors and researchers have sought to settle a long-standing debate over whether elevated blood pressure should be lowered in stroke victims. Lowering blood pressure too s
'/>"/>

Contact: Susan C. Fagan
sfagan@georgiahealth.edu
706-721-0130
University of Georgia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. One Month after Major Quake, Ongoing Crises for Haitian Children
2. Ex-President Clinton Said To Be Fine After Heart Procedure
3. Bill Clinton Back Home After Heart Procedure
4. After a Stroke, High Risk for a Recurrence
5. Women Need More Help After Heart Attack
6. Afternoon Nap Might Make You Smarter
7. Access to Mammograms Drops After Guidelines Change
8. Two Babies Born a Year Apart After Ovary Transplant
9. Vitamin B3 May Help Repair Brain After a Stroke
10. HIV drug that protects a fetus should be avoided for one year after childbirth, researchers say
11. Doctor Joseph Racanelli is Helping Christina Get Back Her Shape After Brutal Attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... medical system developed two centuries ago by a German ... healing method though conventional medicine still views it with ... principles of homeopathy on the idea of "like cures ... or China bark was prescribed to combat malaria but ...
... illness, elective surgeries such as cardiology and cancer, among ... to start overseas marketing of India as a medical ... formalities for marketing medical facilities to a global audience ... process of price-banding of hospitals in various cities by ...
... The British government may approve the fertility law so that ... genes of their “designer” babies. The UK government highlighted more ... be totally reappraised in its proposed update of the 1990 ... governments are possibly approving the new law which allows scientists ...
... or those who have long working hours face increased risk ... is. Infact employees who work overtime were 61 percent ... those who didn't. ,Previous studies had established a ... certain occupations, industries or companies. It has been for the ...
... risk of developing inflammatory disorders like rheumatoid arthritis ... and vegetables like oranges, carrots and sweetcorn. //, ... of which are found in brightly-coloured fruit and ... body against the oxidative damage and inflammation. ...
... ICU of the hospitals may face an increased risk of ... the August issue // of Critical Care Medicine., ,Researchers ... two intensive care units at an academic hospital, a medical ... (CCU), experienced an adverse event. Because these patients are among ...
Cached Medicine News:Health News:Popularity Of Homeopathy On The Increase 2Health News:Popularity Of Homeopathy On The Increase 3Health News:Promoting Medical Tourism In India 2Health News:All Work And No Play Makes Jack A Dull Boy 2
(Date:12/15/2014)... Pa. , Dec. 15, 2014  Inovio ... today it has been added to the NASDAQ ... Biotechnology Index will become effective upon market open ... Biotechnology Index is designed to track the performance ... classified as either biotechnology or pharmaceutical according to ...
(Date:12/15/2014)... 2014  Colorado and Washington State ... of cannabis. Oregon , Alaska ... prohibition during the November 2014 elections. Photo ... The benefits of legalizing cannabis are ... like the increased tax revenue for state and local governments, ...
(Date:12/15/2014)... MEADOWS, N.Y. , Dec. 15, 2014 ... the SPL (Structured Product Labeling) markup language standard, content ... the understanding and skills to work with the standard. ... a series of three webinars on the benefits and ... three one-hour webinars will be facilitated by Howard ...
Breaking Medicine Technology:Inovio Pharmaceuticals Added to NASDAQ Biotechnology Index 2Inovio Pharmaceuticals Added to NASDAQ Biotechnology Index 3Inovio Pharmaceuticals Added to NASDAQ Biotechnology Index 4CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3
... Mich., May 16, 2011 Perrigo Company (Nasdaq: ... approval from the U.S. Food and Drug Administration for its ... and cool mint), a generic version of Zantac 150®. We ... Zantac 150 (ranitidine) is indicated for the relief of heartburn ...
... Dune Medical Devices, Inc. today announced that ... accepted for filing the company,s Pre-Market Approval (PMA) ... mean that the PMA application was sufficiently complete ... believes MarginProbe represents a breakthrough technology that may ...
Cached Medicine Technology:Perrigo Announces FDA Final Approval for Ranitidine 150 - Generic Equivalent to Zantac 150® 2FDA Formally Accepts Dune Medical's MarginProbe™ System Pre-Market Approval (PMA) Application and Grants Expedited Review Status 2
... Receiver is an optional component that ... outdoor and difficult environments. AeroScout Location ... measurement capabilities packaged in small, easy ... conditions. The Location Receiver receives transmissions ...
Integrate RFID and bar code technology with the new DR1000 Dual RFID/Bar Code Reader by Precision Dynamics Corporation (PDC). It provides an easy migration from bar codes to RFID tags for healthcare ...
... The SATO RFID printer reads, writes ... printing a visual image, text or barcode ... RFID printers are ideal for a range ... Access Control, Asset Tracking, Baggage Tagging, Retail ...
... only task-critical information to the operator ... Up to 14 additional computers can ... the facility using a dedicated local ... and administrators can all access the ...
Medicine Products: