Navigation Links
Blood-pressure-lowering drug after stroke aids recovery, study finds
Date:10/21/2011

Athens, Ga. A commonly prescribed blood pressure-lowering medication appears to kick start recovery in the unaffected brain hemisphere after a stroke by boosting blood vessel growth, a new University of Georgia study has found.

The discovery, based on a study using rats and published recently in the online journal PLoS ONE, occurred only because the team, led by Susan Fagan, professor of clinical and administrative pharmacy at the UGA College of Pharmacy, struck a new path in stroke research by examining the healthy side of brain after the stroke occurred.

"I'm very excited because I think we can harness the restorative properties of the contralesional hemispherethe other side of the brainwith drug therapies," Fagan said. "When most researchers study stroke they compare the animal's side of the brain that's damaged to the opposite side, assuming that that side is normal or not affected."

For the study, Fagan and her team induced strokes in two groups of male Wistar rats by blocking a major artery in the brain. A third group of placebo, or sham, animals did not experience strokes so that scientists could compare healthy brain hemispheres across all groups. One group received a single dose of saline solution; the other received a dose of the blood pressure drug candesartan. The placebo group received no treatment.

Animals treated with candesartan displayed higher levels of growth factors that aid with the formation of new blood vessels in the brain, a result that confirmed that of earlier studies from the lab. However, the study revealed a previously unobserved phenomenon: Different types of growth factors dominated different hemispheres in the brain, which suggests that candesartan could have healing properties beyond the area of damage.

Doctors and researchers have sought to settle a long-standing debate over whether elevated blood pressure should be lowered in stroke victims. Lowering blood pressure too s
'/>"/>

Contact: Susan C. Fagan
sfagan@georgiahealth.edu
706-721-0130
University of Georgia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. One Month after Major Quake, Ongoing Crises for Haitian Children
2. Ex-President Clinton Said To Be Fine After Heart Procedure
3. Bill Clinton Back Home After Heart Procedure
4. After a Stroke, High Risk for a Recurrence
5. Women Need More Help After Heart Attack
6. Afternoon Nap Might Make You Smarter
7. Access to Mammograms Drops After Guidelines Change
8. Two Babies Born a Year Apart After Ovary Transplant
9. Vitamin B3 May Help Repair Brain After a Stroke
10. HIV drug that protects a fetus should be avoided for one year after childbirth, researchers say
11. Doctor Joseph Racanelli is Helping Christina Get Back Her Shape After Brutal Attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... (PRWEB) August 21, 2014 Living in ... the atmosphere that comes along with it. A quality ... sure that such amenities are available. , ... in Fayetteville, Georgia and Community Association Management, LLC made ... American Parks Company to provide an additional amenity for ...
(Date:8/21/2014)... For many people, finding motivation to exercise is a challenge. ... the approach of Zombies, Run!one of more than 31,000 health ... the growing number of apps that use games to increase ... mobile fitness app makers looking to cash in to help ... to exercise remains to be seen. , "It,s just been ...
(Date:8/21/2014)... the environmental source of fungal infections that have been ... literally grows on trees. , The discovery is based ... spent the summer gathering soil and tree samples from ... the fungus named Cryptococcus gattii (CRIP-to-cock-us ... number of species including C. gattii , causes ...
(Date:8/21/2014)... 2014 (HealthDay News) -- Being born at a low birth ... diabetes, a new study suggests. The findings may partly ... has a high prevalence of low birth weight, the researchers ... found that those with a low birth weight were 13 ... with a normal birth weight. The risk of diabetes was ...
(Date:8/21/2014)... 21, 2014 A new study published ... increase in disability associated with speech problems from 2001-02 ... than 15% increase in disability associated with hearing problems. ... rising numbers of children who are experiencing communication disorders, ... , On a broader level, the new study, ...
Breaking Medicine News(10 mins):Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 3Health News:Playing hunger games: Are gamified health apps putting odds in your favor? 2Health News:Fungus deadly to AIDS patients found to grow on trees 2Health News:Low Birth Weights May Put Black Women at Risk for Diabetes 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 3
... says , , FRIDAY, May 23 (HealthDay News) -- A new ... diabetes, but more research on possible cardiovascular risks is needed ... Preliminary results on the drug, succinobucol, have been presented at ... 24 issue of The Lancet . , "There is ...
... Linkwell,Corporation (Linkwell) (OTC Bulletin Board: LWLL), a ... disinfectants in China,announced today that it was ... relief efforts. The Chinese government, non-government,organizations (NGOs) ... scale in response to the earthquake in ...
... 23 Memorial University,Medical Center (MUMC) now offers ... small incision in the belly button. It,s called ... surgeons nationwide,are skilled in the SILS technique. One ... SILS, Senkowski can remove the gallbladder through a,1cm. ...
... 5,000 ,Medal of Honor, books and DVDs to local ... Alliance and the,Congressional Medal of Honor Foundation donated 5,000 ... Valor Beyond the Call of,Duty," to California schools., ... and deceased,veterans, including nearly 20 from California, who hold ...
... fitness industry!, JACKSONVILLE, Fla., May 23 The ... television shows, movies and interest in,fun dance fitness programs. ... right here in Jacksonville! This month,they will be bringing ... Kevin B. Maddox. But what are you to do ...
... in Discovery Green Park, HOUSTON, May 23 ... year,s presidential election and the cost of health care,continuing ... (HJMHF) will offer Houston residents a fun and informative,opportunity ... The multicultural health event, which will kick off ...
Cached Medicine News:Health News:New Antioxidant Drug Shows Promise Against Diabetes 2Health News:Linkwell Corporation Runs 24/7 Disinfectant Operations to Support China's Earthquake Relief Efforts 2Health News:Linkwell Corporation Runs 24/7 Disinfectant Operations to Support China's Earthquake Relief Efforts 3Health News:SILS Surgical Technique Now Available at MUMC 2Health News:TriWest Teaches California Kids About Veteran's Sacrifice, Courage 2Health News:Dance Trance Fitness(TM) and SyncLive(TM) Broadcast LIVE from Jacksonville! 2Health News:Announcing the 2nd Annual Houston Juneteenth Multicultural Health Festival 2
(Date:8/21/2014)... , Aug. 21, 2014   Royal Philips ... today announced it has received 510(k) clearance from ... its precision planning application for Transcatheter Aortic-Valve Implantation ... application provides interventionalists with pre-procedural, high-precision positioning to ... TAVI planning application is available as part of ...
(Date:8/20/2014)... 2014 Northstar Global Business Services, Inc., ... of hard work from many talented specialists, the ... and package design.  The new formulation for Snorenz ... the product due to overwhelming evidence of increased ... Nighttime will also include these vitamins, as well ...
(Date:8/20/2014)... 2014  The National Association of Drug Diversion ... by the real-time, pseudoephedrine (PSE) blocking system in ... Exchange (NPLEx), automatically blocks unlawful pseudoephedrine sales and ... and make arrests. Data released by NPLEx shows ... blocked the sale of more than 32,890 boxes of ...
Breaking Medicine Technology:Philips receives FDA 510(k) Clearance for TAVI Precision Treatment Planning Application 2Philips receives FDA 510(k) Clearance for TAVI Precision Treatment Planning Application 3Northstar completes the first phase of its new retail strategy and prepares to ship reformulated Snorenz with all new packaging 2Michigan's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... Sinovac Biotech Ltd. (Amex:,SVA), a leading provider of ... the clinical trials for its pandemic influenza,vaccines. Sinovac ... State Food,and Drug Administration (SFDA) to commence Phase ... whole viron inactivated vaccine and Phase I and,II ...
... Phase I Clinical Trial of Proprietary siRNA Molecule in Acute ... ... 19 Quark Pharmaceuticals, Inc., a,development-stage pharmaceutical company focused on discovering ... dosing in humans of its proprietary product,candidate, AKIi-5, a siRNA compound ...
Cached Medicine Technology:Sinovac Provides Update in Pandemic Influenza Vaccines (H5N1) Phase II Clinical Trials 2Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans 2Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans 3Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans 4
... The new Finnpipette Focus from Thermo Labsystems ... uncompromising performance. Advanced features such as ... fine volume adjustment on microvolumes help to ... single channel pipettes. The new interchangeable handle ...
This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,407-0) or contact custom...
... Finnpipette Digital offers improved ergonomics for ... handle, modified grippy finger rest and ... comfort and efficiency. Finnpipette Digitals also ... gearing mechanism (pat. pend.) and super ...
... Pipetman Ultra is a fully adjustable, air-displacement ... It is the latest member of the ... characteristics: robustness, accuracy, and precision. We also ... feedback from our customers. Eight models cover ...
Medicine Products: