Navigation Links
Blood pressure drugs may lengthen lives of melanoma patients
Date:9/20/2011

COLUMBUS, Ohio Beta-blocker drugs, commonly used to treat high blood pressure, may also play a major role in slowing the progression of certain serious cancers, based on a new study.

A review of thousands of medical records in the Danish Cancer Registry showed that patients with the skin cancer melanoma, and who also were taking a specific beta-blocker, had much lower mortality rates than did patients not taking the drug.

The report, published in the current issue of the journal Cancer Epidemiology, Biomarkers & Prevention, summarized the work of a team of researchers at Ohio State University's Institute for Behavioral Medicine Research (IBMR) and the Comprehensive Cancer Center.

If the results are confirmed in a planned clinical trial, this might be an additional adjunct treatment for cancer patients facing a poor prognosis.

At the center of this research is the fact that certain molecules that play important roles in the immune system also appear to promote both tumor growth and metastasis, the shedding and spreading of tumor tissue to other parts of the body.

"The work started with some earlier studies where we discovered that certain tumor cells had receptors to two specific catecholamine stress hormones epinephrine and norepinephrine," explained Ron Glaser, professor of molecular virology, immunology and medical genetics and director of the IBMR.

"When either of these hormones bind to the tumor cell receptors, it stimulates the production of vascular endothelial growth factor (VEGF), interleukin-8 (IL-8), interleukin-6 (IL-6) and certain matrix metalloproteins all molecules known to stimulate blood flow to tumors, enhancing their growth, and promoting metastasis."

The earlier studies first used tissue from a nasopharyngeal carcinoma cell line, and later from both multiple myeloma and melanoma cell lines. When treated with the beta-blocker propranol, all cells stopped producing the t
'/>"/>

Contact: Ronald Glaser
glaser.1@osu.edu
614-292-5526
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Inflammatory Bowel Ups Risk for Blood Clots
2. Bowel disease link to blood clots
3. Local Blood Supply Impacted by Wednesdays Severe Snow Storm
4. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
5. China Cord Blood Corporation Warrant Registration Statement Declared Effective by SEC
6. NIH grants to Childrens Hospital will advance novel stem cell treatments for blood disorders
7. Bilberry Seems to Act Against Blood Sugar
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. UCR researcher identifies mechanism malaria parasite uses to spread in red blood cells
10. NHLBI, CDC launch surveillance and research program for inherited blood diseases
11. IOM report declares high blood pressure a neglected disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... 20, 2014 Hope For The Warriors® ... Celebration to be hosted in Washington, DC on Thursday, ... This signature event honors the courage of our wounded ... fallen. Proceeds from the Got Heart, Give Hope® Celebration ... dedicated to restoring a sense of self, restoring the ...
(Date:8/20/2014)... WA (PRWEB) August 20, 2014 “Have you ... an auto accident and personal injury lawyer serving the greater ... that incident? If so, then keep reading . , ... that individuals injured in an auto accident can use to ... Jones explains that a personal injury insurance claim will allow ...
(Date:8/20/2014)... The “Human Insulin Market by ... Premixed), Modern Human Insulin (Rapid Acting, Long Acting, ... Tresiba, Others) - Forecast to 2019” provides a ... current market trends,and strategies impacting the global human ... of the revenue and share analysis. , Browse ...
(Date:8/20/2014)... Burlingame, CA (PRWEB) August 20, 2014 ... publishers to speech-enable their websites and create a new ... users to consume content by listening to a narration ... in multiple reader genders and languages. Users can ... work, check social networks, while consuming content. ...
(Date:8/20/2014)... New York (PRWEB) August 20, 2014 Over ... the Global Bureau of Disease, low back pain is the ... the most common reasons for missed work. Americans spend at ... this pain. , Most cases of back pain are not ... mechanical (non-organic) origin. , For example, Pete, a busy accountant, ...
Breaking Medicine News(10 mins):Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Washington, DC 2Health News:Five Questions to Determine Who Qualifies for a Personal Injury Claim Recently Released by The Jones Firm in Recent Article 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Mixberry Media, First To Offer Article Voice Narration with Integrated Audio Advertising 2Health News:Physical Therapists Learn to Relieve Low Back Pain 2
... diagnosis, treatment, researchers say , MONDAY, Oct. 5 (HealthDay News) ... on the diagnosis and treatment of one of the most ... new genes associated with head and neck cancer. , Previously, ... and neck cancer, which includes cancers of the mouth, nose, ...
... ... of growth charts/BMI, Children,s National pediatrician stresses the need for clear communication about seriousness ... ... explain the seriousness of a child being overweight may not be reaching the child,s ...
... Oct. 5 With the school season underway, New York ... to please organize blood drives at their schools, a process ... learning experience for both students and the surrounding community. , ... Brothers, a middle school educator. Now in its ...
... 5 Vocollect Healthcare Systems, Inc. and American ... contribute towards a more timely and unified Electronic ... This alliance interfaces the market,s top performing interactive ... software and EMR offering. , The ...
... In conjunction with its celebration of Case Management Week (Oct. ... the winner of its second annual $1,000 Patricia McCollom Scholarship ... of Fort Bragg, N.C. A case manager with the Army,s ... a highly qualified field of nominees who had either applied, ...
... than 7,000 people are diagnosed with head and neck cancer ... in death. These cancers include tumours of the mouth, ... to the sexually transmitted infection, HPV-16. Scientists at Liverpool ... to look for genes that indicated infection. The ...
Cached Medicine News:Health News:Gene Discovery May Advance Head and Neck Cancer Therapy 2Health News:Pediatrics: Doctors Must Find Better Ways to Talk To Parents about Childhood Obesity 2Health News:Pediatrics: Doctors Must Find Better Ways to Talk To Parents about Childhood Obesity 3Health News:Blood Drives Offer Lessons in Learning 2Health News:Blood Drives Offer Lessons in Learning 3Health News:American HealthTech and Vocollect Healthcare Systems Announce an Alliance to Deliver Unified Electronic Medical Records 2Health News:American HealthTech and Vocollect Healthcare Systems Announce an Alliance to Deliver Unified Electronic Medical Records 3Health News:CCMC Celebrates Case Management Week (Oct. 11-17) With Second Annual Patricia McCollom Scholarship 2Health News:DNA test could be key to targeting treatments for head and neck cancer 2
(Date:8/19/2014)... British Columbia and MENLO PARK, Calif. ... (OTCQB: DMPI) ("DelMar" "the company") announced today a protocol ... trial had been filed with the U.S. Food and Drug ... 50mg/m 2 has been opened at three clinical trial ... company also confirmed that gross proceeds of US$2.9 million have ...
(Date:8/19/2014)... 2014 ,Weight Loss- Market Analysis, ... report provides comprehensive insights about phase III pipeline drugs ... of the report is to establish the understanding for ... across the different countries and regions. While the leading ... also provides details on the drug master filings across ...
(Date:8/18/2014)... Israel , Aug. 19, 2014 Immune ... Stockholm : "IMNP"), a biotechnology company, today announced ... its common stock on the NASDAQ Capital Market has been ... NASDAQ OMX Group. IMMUNE,s common stock is expected to begin ... trading on August 21, 2014 under the symbol IMNP. ...
Breaking Medicine Technology:DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 2DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 3DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 4DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 5DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 6DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 7Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 3Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 4Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 2Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 3Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 4
... Miami HEAT forward Juwan Howard and Basketball Hall of Famer ... for Adolescent Health and Medicine (SAHM) today to bring ... for Teens is a national awareness campaign designed to ... against serious and potentially life-threatening diseases. To ...
... 2011 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. (Nasdaq: CHBT ... of probiotics products in China, today reported its unaudited financial results ... year ended December 31, 2010. Third ... Net sales increased 39.0% y-o-y to $32.4 million; ...
Cached Medicine Technology:Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 2Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 3Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 4Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 2China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 3China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 4China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 6China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 7China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 8China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 9China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 10China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 11
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: