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Blood pressure drugs halt pancreatic cancer cell growth, Jefferson researchers find
Date:4/14/2008

Research in San Diego.

The researchers also found that blocking AT1R affects p21, a gene that regulates the cell cycle. We found that blocking this receptor can cause cell cycle arrest, she notes.

This is really exciting because the role of this receptor has never been known, Dr. Arafat says. Its never been connected to cell division or apoptosis. Were also now further exploring the mechanisms involved. The exciting thing is that this receptor already has so many available pharmaceutical blockers on the market. Ultimately, the group hopes to be able to test these agents in human trials, she says.


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Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

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