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Blood-flow detector software show promise in preventing brain damage
Date:8/31/2007

from two staples of the pediatric intensive care unitan old-fashioned arterial blood pressure monitor and an oxygen meter that uses beams of infrared light to estimate oxygen saturation in the brain.

The software essentially makes these two devices talk to each other, researchers explain, showing in a continuous stream the interplay between blood pressure and oxygen levels, whether the brain is coping with pressure changes, and more importantly, what blood pressure range is conducive to that. This intricate interplay between oxygenation and blood flow was the big unknown in what is indeed a simple equation, and now weve pinpointed the level where arterial blood pressure needs to be in order to promote healing in the injured brain, Brady says.

In traumatic brain injuries, some brain damage occurs on impact, but much damage and indeed many deaths occur in the critical two-to-five-day window following the injury, a critical time when brain function must be monitored to ward off damage. This is when and where the new system will be most useful, researchers say. The technique could be also used in premature babies, who are particularly prone to ischemic strokes and bleeding in the brain because of their brains immature self-regulatory mechanisms and their fragile blood vessels.


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Contact: Kim Martin
kmartin7@jhmi.edu
410-516-4958
Johns Hopkins Medical Institutions
Source:Eurekalert

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