Navigation Links
Blood-flow detector software show promise in preventing brain damage
Date:8/31/2007

Researchers from the Johns Hopkins Childrens Center and Cambridge University in England have designed an automated means of continuously tracking potentially dangerous changes in blood flow to the brain in real time, a system that shows promise for preventing brain damage and death in children with head injuries.

A report on the work, including results of preliminary testing in baby pigs, will appear in the October issue of Stroke. Brain trauma is a top killer of children in the United States, with some 475,000 children suffering brain injuries each year, according to the U.S. Centers for Disease Control. More tests are needed, but we have demonstrated the value of gathering much more detailed information over time about what safe levels of pressure and oxygen are in children, says Ken Brady, M.D., a critical-care specialist at the Childrens Center who led the study. Despite our ability to monitor pressure and oxygen levels, we have desperately needed more information about what are optimal levels for damage prevention in children, Brady says. Not knowing that is much like flying a plane in a fog, but this new software is helping us map safe terrain and danger zones in blood pressure.

Healthy brains regulate blood flow and oxygen levels during drops and spikes in blood pressure, but injured brains may lose this fail-safe mechanism, leading to oxygen starvation and permanent brain damage. Although monitors have long been able to track blood pressure and blood flow to the brain, the Hopkins-Cambridge team created a system that for the first time precisely determines the breakpoint at which the brain begins to lose its ability to cope with changes in blood pressure.

The software does this, researchers say, by gauging minute shifts in blood pressure and oxygenation every 60 seconds and alerting doctors when they approach critical levels. Using a software program developed by two Cambridge scientists, Hopkins doctors fed data into a computer from two staples of the pediatric intensive care unitan old-fashioned arterial blood pressure monitor and an oxygen meter that uses beams of infrared light to estimate oxygen saturation in the brain.

The software essentially makes these two devices talk to each other, researchers explain, showing in a continuous stream the interplay between blood pressure and oxygen levels, whether the brain is coping with pressure changes, and more importantly, what blood pressure range is conducive to that. This intricate interplay between oxygenation and blood flow was the big unknown in what is indeed a simple equation, and now weve pinpointed the level where arterial blood pressure needs to be in order to promote healing in the injured brain, Brady says.

In traumatic brain injuries, some brain damage occurs on impact, but much damage and indeed many deaths occur in the critical two-to-five-day window following the injury, a critical time when brain function must be monitored to ward off damage. This is when and where the new system will be most useful, researchers say. The technique could be also used in premature babies, who are particularly prone to ischemic strokes and bleeding in the brain because of their brains immature self-regulatory mechanisms and their fragile blood vessels.


'/>"/>
Contact: Kim Martin
kmartin7@jhmi.edu
410-516-4958
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. Potential Key to Brain Blood-Flow Disorders Explored by Scientists
2. Prototype Detector detects Anthrax Quickly
3. Novel Metal Detector To Measure Zinc Level In Humans
4. Gold Nanoparticles Are Good Detectors Biological Toxins
5. In Search of Truth - Lie Detector
6. Africa Set to Control Malaria Using Specialized Software
7. India, a Hot Destination? Software or Sex, Indians are the Best!
8. Safe Software A Must For Doctors
9. New Software to Help Patients
10. Software Tools & Fonts in Seven Indian Languages
11. Computer Software Less Reliable Than Radiologists Eyes in Detecting Cancerous Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Ill. (PRWEB) , ... October ... ... Edwardsville School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer ... healthcare professionals on guideline updates for the primary prevention of cardiovascular diseases ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Ellevate Network, the ... business to advocate for action towards gender equality at their inaugural Summit in New ... the globe, and reached a social audience of over 3 million. To watch the ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... 12, 2017 , ... Dr. Parsa Mohebi, the Los Angeles ... to the newly revamped Cosmetic Town journal section, featuring articles written ... known as Follicular Unit Extraction (FUE). , Dr. Mohebi says “I ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... for their devotion to personalized service, SMP Pharmacy Solutions announces ... the South Florida Business Journal,s 50 Fastest-Growing Companies, and listed ... national specialty pharmacy has found its niche.  To that end, ... honored by SFBJ as the 2017 Power Leader in Health ... his award in October, Bardisa said of the three achievements, ...
(Date:9/22/2017)... ROCKVILLE, Md. , Sept. 22, 2017  As ... by Republican Senators Bill Cassidy (R-LA) and ... Kalorama Information notes that the medical device industry is ... the medical device tax, the 2.3% excise tax on ... Act.  But they also want covered patients, increased visits ...
(Date:9/18/2017)... PROVIDENCE, R.I. , Sept. 18, 2017 ... in the fields of bioinformatics and immune ... to develop a protective avian influenza A (H7N9) vaccine. ... is distantly related to seasonal influenza and ... approaches, which rely on prior exposure to be ...
Breaking Medicine Technology: