Navigation Links
Blood-flow detector software show promise in preventing brain damage
Date:8/31/2007

Researchers from the Johns Hopkins Childrens Center and Cambridge University in England have designed an automated means of continuously tracking potentially dangerous changes in blood flow to the brain in real time, a system that shows promise for preventing brain damage and death in children with head injuries.

A report on the work, including results of preliminary testing in baby pigs, will appear in the October issue of Stroke. Brain trauma is a top killer of children in the United States, with some 475,000 children suffering brain injuries each year, according to the U.S. Centers for Disease Control. More tests are needed, but we have demonstrated the value of gathering much more detailed information over time about what safe levels of pressure and oxygen are in children, says Ken Brady, M.D., a critical-care specialist at the Childrens Center who led the study. Despite our ability to monitor pressure and oxygen levels, we have desperately needed more information about what are optimal levels for damage prevention in children, Brady says. Not knowing that is much like flying a plane in a fog, but this new software is helping us map safe terrain and danger zones in blood pressure.

Healthy brains regulate blood flow and oxygen levels during drops and spikes in blood pressure, but injured brains may lose this fail-safe mechanism, leading to oxygen starvation and permanent brain damage. Although monitors have long been able to track blood pressure and blood flow to the brain, the Hopkins-Cambridge team created a system that for the first time precisely determines the breakpoint at which the brain begins to lose its ability to cope with changes in blood pressure.

The software does this, researchers say, by gauging minute shifts in blood pressure and oxygenation every 60 seconds and alerting doctors when they approach critical levels. Using a software program developed by two Cambridge scientists, Hopkins doctors fed data into a computer from two staples of the pediatric intensive care unitan old-fashioned arterial blood pressure monitor and an oxygen meter that uses beams of infrared light to estimate oxygen saturation in the brain.

The software essentially makes these two devices talk to each other, researchers explain, showing in a continuous stream the interplay between blood pressure and oxygen levels, whether the brain is coping with pressure changes, and more importantly, what blood pressure range is conducive to that. This intricate interplay between oxygenation and blood flow was the big unknown in what is indeed a simple equation, and now weve pinpointed the level where arterial blood pressure needs to be in order to promote healing in the injured brain, Brady says.

In traumatic brain injuries, some brain damage occurs on impact, but much damage and indeed many deaths occur in the critical two-to-five-day window following the injury, a critical time when brain function must be monitored to ward off damage. This is when and where the new system will be most useful, researchers say. The technique could be also used in premature babies, who are particularly prone to ischemic strokes and bleeding in the brain because of their brains immature self-regulatory mechanisms and their fragile blood vessels.


'/>"/>
Contact: Kim Martin
kmartin7@jhmi.edu
410-516-4958
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. Potential Key to Brain Blood-Flow Disorders Explored by Scientists
2. Prototype Detector detects Anthrax Quickly
3. Novel Metal Detector To Measure Zinc Level In Humans
4. Gold Nanoparticles Are Good Detectors Biological Toxins
5. In Search of Truth - Lie Detector
6. Africa Set to Control Malaria Using Specialized Software
7. India, a Hot Destination? Software or Sex, Indians are the Best!
8. Safe Software A Must For Doctors
9. New Software to Help Patients
10. Software Tools & Fonts in Seven Indian Languages
11. Computer Software Less Reliable Than Radiologists Eyes in Detecting Cancerous Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... San Diego, CA (PRWEB) , ... June 24, 2016 , ... ... up with the American Cancer Society and the Road To Recovery® program to drive ... care to seniors and other adults to ensure the highest quality of life and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... WAYNE, Pa. , June 23, 2016 ... provider, will launch its next generation clinical outcomes platform, Bracket ... DIA Meeting held on June 26 – 30, 2016 in ... 6.0, the first electronic Clinical Outcome Assessment product of its ... DIA Booth #715. Bracket eCOA 6.0 is a ...
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
(Date:6/23/2016)... , June 23, 2016  Experian Health, ... and transforming the patient payment and care ... innovative new products and services that will ... revenue cycle offerings. These award-winning solutions will ... workflows, remain compliant in an ever-changing environment ...
Breaking Medicine Technology: