And in another trial, the drug apixaban (Eliquis) was pitted against another mainstay blood thinner, enoxaparin (Lovenox), in more than 6,500 patients with congestive heart failure at high risk for dangerous clots. Researchers led by Dr. Samuel Goldhaber of Brigham and Women's Hospital and Harvard Medical School found that Eliquis did not outperform Lovenox and was also linked to more bleeding.
The vorapaxar study was funded by drug maker Merck, while Bristol-Myers Squibb and Pfizer supported the Eliquis/Lovenox trial.
There's more on blood thinners at the U.S. National Library of Medicine.
SOURCES: Eugene Braunwald, M.D., professor, medicine, Harvard Medical School, and cardiologist, Brigham and Women's Hospital, Boston; C. Michael Gibson, M.D., chief of clinical research, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston; Gordon F. Tomaselli, M.D., chief of cardiology, Johns Hopkins University, Baltimore, and president, American Heart Association; Nov. 13, 2011, New England Journal of Medicine, online, and presentations, Nov. 13, 2011, annual meeting of the American Heart Association, Orlando, Fla.
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