Navigation Links
Blood Test Helps Docs Assess Breast Cancer Treatment

New tool could allow physicians to determine much sooner if therapy is working

FRIDAY, May 16 (HealthDay News) -- A simple blood test to check levels of circulating tumor cells can help doctors more accurately assess how well treatments are working in women with metastatic breast cancer, according to a Georgetown University Medical Center study.

"It can take several weeks, and sometimes months, to determine if a particular cancer treatment is working, because it can take that long to observe any significant radiographic changes in tumor size or appearance," principal investigator Dr. Minetta Liu, of Georgetown's Lombardi Comprehensive Cancer Center, said in a prepared statement.

"Right now, we have to rely on radiology studies such as CT scans, ultrasound, and the like to determine whether or not there is disease progression. With this new blood test, we have another reliable tool that may allow us to determine much sooner if a therapy is ineffective, so that we can change therapy earlier and potentially make more significant improvements in survival," Liu explained.

In this study, Liu and colleagues measured the number of circulating tumor cells (CTC) in blood samples collected from metastatic breast cancer patients every three to four weeks. The women were receiving various treatments, including chemotherapy, endocrine therapy, and combination therapy with a biologic agent.

The researchers found that 71 percent of patients with a CTC count of five or greater had disease progression, compared with 66 percent of patients with a CTC count of less than five.

"A CTC count of five or greater at the time of restaging was associated with a 5.32-fold increase in a patient's chances of having disease progression compared to CTC counts of less than five," Liu said. "CTC assessments should be used as a surrogate marker for treatment efficacy and disease responsiveness. Changes in CTC results from less than five to greater than or equal to five over time may herald disease progression."

The findings were released online May 15 in advance of the annual meeting of the American Society of Clinical Oncology, in Chicago.

The study was funded by Veridex, LLC, which makes the technology used in this study to measure CTC levels. Liu has received payments from Veridex for speaking engagements.

More information

The U.S. National Cancer Institute has more about breast cancer treatment.

-- Robert Preidt

SOURCE: Georgetown University Medical Center, news release, May 15, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study suggests blood test can help improve treatment outcomes for breast cancer patients
2. CardioDynamics Announces Significant ICG Study with Nearly Three Times the National Average Blood Pressure Control Rates at the American Society for Hypertension Annual Scientific Meeting
3. Pollution Particles Impair Blood Vessel Function
4. Aspirin at Bedtime Lowers Blood Pressure
5. Blood-Thinner No Help for Dialysis Treatment
6. High Blood Pressure, Cholesterol Associated With Eye Disease
7. Air Pollution Linked to Blood Clots in Legs
8. High Blood Pressure Still Slipping Past Doctors
9. Omron Makes Blood Pressure Monitoring Easy for Women at Any Stage of Life, Including Pregnancy
10. NxStage Announces Supply Agreement With Kawasumi Laboratories for Blood Tubing Sets
11. High Blood Sugar Tied to Pregnancy Complications
Post Your Comments:
(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Issue 52" report to their offering. ... treatment creates a favourable commercial environment for MedImmune to enter. ... base that will serve to drive considerable growth for effective ... serve to cap sales considerably, but development is still in ...
(Date:6/23/2016)... 2016 , , , WHEN: ... 2016 , , , , LOCATION: , , , Online, ... , , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global ... Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager ... pharmaceutical industry is witnessing an exceptional era. Several new demand spaces, ...
(Date:6/23/2016)... the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. Colombia ... ... Sandra ... ... Astellas is a pharmaceutical company ...
Breaking Medicine Technology: