Navigation Links
Blood Test Helps Docs Assess Breast Cancer Treatment
Date:5/16/2008

New tool could allow physicians to determine much sooner if therapy is working

FRIDAY, May 16 (HealthDay News) -- A simple blood test to check levels of circulating tumor cells can help doctors more accurately assess how well treatments are working in women with metastatic breast cancer, according to a Georgetown University Medical Center study.

"It can take several weeks, and sometimes months, to determine if a particular cancer treatment is working, because it can take that long to observe any significant radiographic changes in tumor size or appearance," principal investigator Dr. Minetta Liu, of Georgetown's Lombardi Comprehensive Cancer Center, said in a prepared statement.

"Right now, we have to rely on radiology studies such as CT scans, ultrasound, and the like to determine whether or not there is disease progression. With this new blood test, we have another reliable tool that may allow us to determine much sooner if a therapy is ineffective, so that we can change therapy earlier and potentially make more significant improvements in survival," Liu explained.

In this study, Liu and colleagues measured the number of circulating tumor cells (CTC) in blood samples collected from metastatic breast cancer patients every three to four weeks. The women were receiving various treatments, including chemotherapy, endocrine therapy, and combination therapy with a biologic agent.

The researchers found that 71 percent of patients with a CTC count of five or greater had disease progression, compared with 66 percent of patients with a CTC count of less than five.

"A CTC count of five or greater at the time of restaging was associated with a 5.32-fold increase in a patient's chances of having disease progression compared to CTC counts of less than five," Liu said. "CTC assessments should be used as a surrogate marker for treatment efficacy and disease responsiveness. Changes in CTC results from less than five to greater than or equal to five over time may herald disease progression."

The findings were released online May 15 in advance of the annual meeting of the American Society of Clinical Oncology, in Chicago.

The study was funded by Veridex, LLC, which makes the technology used in this study to measure CTC levels. Liu has received payments from Veridex for speaking engagements.

More information

The U.S. National Cancer Institute has more about breast cancer treatment.



-- Robert Preidt



SOURCE: Georgetown University Medical Center, news release, May 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study suggests blood test can help improve treatment outcomes for breast cancer patients
2. CardioDynamics Announces Significant ICG Study with Nearly Three Times the National Average Blood Pressure Control Rates at the American Society for Hypertension Annual Scientific Meeting
3. Pollution Particles Impair Blood Vessel Function
4. Aspirin at Bedtime Lowers Blood Pressure
5. Blood-Thinner No Help for Dialysis Treatment
6. High Blood Pressure, Cholesterol Associated With Eye Disease
7. Air Pollution Linked to Blood Clots in Legs
8. High Blood Pressure Still Slipping Past Doctors
9. Omron Makes Blood Pressure Monitoring Easy for Women at Any Stage of Life, Including Pregnancy
10. NxStage Announces Supply Agreement With Kawasumi Laboratories for Blood Tubing Sets
11. High Blood Sugar Tied to Pregnancy Complications
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in ... ways they remain in the eye of the beholder, according to experts who offered ... The American Journal of Managed Care. For the full issue, click here . ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: