Navigation Links
Blood Stored Too Long May Threaten Patient Safety
Date:7/21/2011

THURSDAY, July 21 (HealthDay News) -- New research links medical problems caused by blood transfusion to the breakdown of red blood cells during blood storage. The findings suggest that a better way to store blood is needed.

When transfused, older blood or high amounts of blood can lead to complications, including infection, kidney and lung failure and death, said study co-author Dr. Mark T. Gladwin in a news release from Wake Forest University, which led the study.

The study examines the interaction between nitric oxide (NO) and the byproducts created as red blood cells break down over time. The researchers found that the interaction in older blood can reduce blood flow and perhaps damage tissues in the body.

"When blood sits for a while, some of the cells break down and release their contents, which include molecules of hemoglobin and red blood cell microparticles," said Gladwin, chief of the division of pulmonary, allergy and critical care medicine at the University of Pittsburgh School of Medicine. "These accumulate in the stored bag of blood and are transfused into the patient with the blood. In the bloodstream, the hemoglobin and microparticles bind to and destroy [nitric oxide], a very important molecule that is used by the body to keep blood vessels dilated for normal blood flow."

"Transfusion of stored blood is one of the most common medical therapies," said study senior author Daniel B. Kim-Shapiro, professor of physics and director of the Translational Science Center at Wake Forest University, in the news release. "For example, perhaps we can restore nitric oxide activity that is lost upon transfusion, use preservation solutions that better limit the degradation of blood cells, or develop agents that scavenge free hemoglobin."

Future studies will examine the safety of blood stored more than 14 days. Under current federal guidelines, blood can be stored for up to 42 days.

Each year in the United States more than 5 million people receive blood transfusions, according to the study.

The study is published in the journal Circulation.

More information

For more on blood donations, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCE: Wake Forest University, press release, July 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. FDA Approves Blood Thinner Brilinta for Heart Patients
2. Evolution provides clue to blood clotting
3. Controversial Cholesterol Drug Might Lower Blood Sugar Levels in Diabetics
4. Small Study Suggests Milk, Soy Proteins Lower Blood Pressure Modestly
5. Benefit of blood glucose lowering to near-normal levels remains unclear
6. Pitt, Wake Forest team finds why stored transfusion blood may become less safe with age
7. Penn study shows link between immune system suppression and blood vessel formation in tumors
8. Bettering Social Status Lowers High Blood Pressure Risk
9. Sleep Apnea Linked to Blood Vessel Disorders in Study
10. Cancer patients with blood clots gain no benefit from adding IVCF to fondaparinux
11. Too Much Sitting May Double Womens Risk of Blood Clots
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blood Stored Too Long May Threaten Patient Safety
(Date:5/27/2017)... ... ... In any business, follow up is critical to success. It is the ... treatment, there will always be some patients who can’t or won’t make a immediate ... when it comes to presenting treatment. After the patient leaves, most practices end ...
(Date:5/26/2017)... NEW YORK, NY (PRWEB) , ... May 26, ... ... Advisory Board (SAB) met this week to review more than eighty-nine grant ... both experienced and emerging young scientists in the Parkinson’s field.     , The American ...
(Date:5/26/2017)... ... May 26, 2017 , ... Somnoware, a leading ... sleep monitor with its Somnoware Sleep Device Interface (SDI). Somnoware SDI is a ... operations. With this platform, initializing devices and importing studies are just one-click operations. ...
(Date:5/26/2017)... ... ... On May 24, the Congressional Budget Office (CBO) projected that the amended ... would result in 23 million Americans losing their health insurance by 2026 as compared ... Affordable Care Act (ACA). , “It is clear from the CBO analysis that ...
(Date:5/26/2017)... ... ... Lowe acts as host and helps educate and inform the public using the “Informed” ... reconnect with America as it explores some of the best places to hike and ... inventive new place for a family vacation, and have discovered hiking. Many will agree ...
Breaking Medicine News(10 mins):
(Date:5/18/2017)... -- Bayer announced today that the latest research from across ... 53 rd Annual Meeting of the American Society ... Chicago . The ... and thyroid cancers, as well as lymphomas, and includes ... of copanlisib in patients with relapsed or refractory follicular ...
(Date:5/11/2017)... -- Thornhill Research Inc. ( Toronto, Ontario, Canada ... five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by the U.S. Department ... ( Ottawa, Ontario, Canada ) to ... to patients requiring emergency medical procedures in a ... have been a longtime partner with Thornhill Research ...
(Date:5/10/2017)... 10, 2017 Radiology has become the number ... have also spiraled to the number one ranking as ... than ever before as the most complete and reliable ... with lower back pain an MRI may confirm a ... pain, resulting in entirely different treatment protocols.  In these ...
Breaking Medicine Technology: