Navigation Links
Blood Pressure Drug Might Work Against MS
Date:8/17/2009

Research shows inflammation link between two disorders

MONDAY, Aug. 17 (HealthDay News) -- Dr. Lawrence Steinman has this seemingly crazy idea that a drug commonly used to combat high blood pressure can help prevent the damage done to nerve cells in multiple sclerosis.

But people in the know tend to listen carefully to the ideas of Steinman, a professor of neurology at Stanford University, because one of his ideas was crucial in the development of natalizumab (Tysabri), a now widely used medication that can reduce the incidence of relapses in multiple sclerosis (MS) by two-thirds.

Research exploring Steinman's latest brainstorm appears online Aug. 17 in the Proceedings of the National Academy of Sciences.

Steinman said he got his latest idea after he was prescribed the ACE inhibitor lisinopril (Zestril) for high blood pressure. When he put the drug name into his computer's search engines, vague references to a relationship between the drug's target, angiotensin, and multiple sclerosis started showing up.

An ACE (angiotensin-converting enzyme) inhibitor blocks the activity of an enzyme that converts angiotensin to a form that tightens blood vessels.

"Angiotensin constricts blood vessels in response to standing up, so we don't faint," he said. "Nerve cells are intrinsically tied up with blood vessel walls, and that pathway plays a role in inflammation."

Inflammation also plays a crucial role in multiple sclerosis, in which the body's immune system attacks the myelin sheath of nerve cells in the brain. "We can also argue that inflammation plays a role in hypertension," Steinman said.

Working with researchers from other institutions, he put the idea to a variety of tests, such as examining tissue from brain samples of people with MS. The studies showed significantly elevated levels of the cell receptors for angiotensin and the enzyme blocked by lisinopril and other ACE i
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Mothers Immune System May Block Fetal Treatments for Blood Diseases
2. Cord Blood America Says Balance Sheet Significantly Strengthened in 2009
3. Heroes of Chemistry for saving teeth, clean water, new high blood pressure drug
4. Bayer Statement on U.S. Food and Drug Administration Advice for Patients: Serious Errors with Certain Blood Glucose Monitoring Test Strips
5. BD and PEPFAR Collaboration Will Improve Blood-Drawing Practices in Hospitals and Clinics in Sub-Saharan Africa
6. MRI Simulation of Blood Flow Helps Plan Childs Heart Surgery
7. Cold, Flu or Pneumonia? Answer May Lie in Blood Test
8. U.S. Navy Awards Entegrion Contracts for $4 Million for the Development of Critical Blood Products
9. Memorial Blood Centers Joins Extreme Makeover: Home Edition As Designated Charity
10. Blood transfusion study: Less is more
11. Gut Hormone Could be Key to Blood Sugar
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blood Pressure Drug Might Work Against MS
(Date:10/22/2014)... October 22, 2014 The ... which is dedicated to distribute health information technology ... delivery worldwide announced the development of six key ... expect when receiving healthcare. These are an expansion ... care: “providing care that is respectful of and ...
(Date:10/22/2014)... Best Cheap Hosting USA is among the most ... recently announced that iPower ( http://www.best-cheap-hosting-usa.com/go/iPower/ ) is the ... the world. , “iPower is one of the most ... various kinds of useful products for new and old ... customer service and a number of features which will ...
(Date:10/22/2014)... CA (PRWEB) October 22, 2014 Lintelus, ... Cormier, Sr. Vice President of Sales, will be speaking ... upcoming Meetings Technology Expo on October 28, at the ... be hosting a booth as well as a Tech ... Lintelus Meeting can create a more engaging event experience. ...
(Date:10/22/2014)... Salamon HealthDay Reporter , TUESDAY, ... vitro fertilization (IVF) are only about half as likely as ... technique, new research indicates, and the racial disparity persists even ... 31 percent of white patients became pregnant after IVF, compared ... than 4,000 IVF cycles over two years to tease out ...
(Date:10/22/2014)... 2014 (HealthDay News) -- Measures taken by Firestone officials ... Liberia may have limited the spread of the disease ... The Firestone Natural Rubber Co. provides health services to ... nearby densely populated communities. Between Aug. 1 and ... cases among those 80,000 people. That incidence rate of ...
Breaking Medicine News(10 mins):Health News:The Sullivan Institute for Healthcare Innovation Announces Release of Guiding Principles for Patient Experience-Centered Care 2Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2
... 11 Mothers Against Drunk Driving (MADD) New ... office today showing support for MADD,s Campaign to ... )A key part of MADD,s ... pending in the New York State legislature that ...
... for cardiac rehab programs, , , MONDAY, May 11 (HealthDay News) ... but slower walks are better for losing weight and improving ... found. , Frequent long, slow walks -- 45 minutes to ... six days a week -- were found to burn more ...
... That, are Not Tied to Management or ... (TSX, NYSE: BVF ) shareholders today are being ... special meeting of shareholders scheduled to be held on May ... of the World Bank and former CEO of OMERS as ...
... Older Americans, Nursing Home Residents and Stroke SurvivorsFORT ... largest family-owned and operated senior care provider reports ... of computer technology account for speedier recovery and ... research data demonstrate that 91 percent of CareOne,s ...
... May 11 /PRNewswire-Asia-FirstCall/ -- Jiangbo,Pharmaceuticals, Inc. (OTC Bulletin Board: ... operations in the People,s Republic,of China, today announced that ... Bulletin Board under the new ticker symbol "JGBO" as ... under the ticker symbol "GNPH" at the,end of May ...
... military veterans with ALS and the widow of a military veteran who ... the Tomb of the Unknowns during a ceremony sponsored by The ALS ... ... military veterans with ALS and the widow of a military veteran who ...
Cached Medicine News:Health News:MADD Delivers Nearly 7,000 Petitions to Governor Paterson Urging Ignition Interlocks For All Convicted DWI Offenders 2Health News:Walk Long, Slow and Often to Help the Heart 2Health News:Walk Long, Slow and Often to Help the Heart 3Health News:Former Executive Director of the World Bank and CEO of OMERS Nominated as Directors for Biovail Corporation's Board of Directors 2Health News:Former Executive Director of the World Bank and CEO of OMERS Nominated as Directors for Biovail Corporation's Board of Directors 3Health News:Former Executive Director of the World Bank and CEO of OMERS Nominated as Directors for Biovail Corporation's Board of Directors 4Health News:State-of-the-Art Technology and Hotel-Like Environment Get CareOne's Rehab Patients Home Quicker 2Health News:State-of-the-Art Technology and Hotel-Like Environment Get CareOne's Rehab Patients Home Quicker 3Health News:Jiangbo Pharmaceuticals Announces New Ticker (JGBO) and CUSIP 2Health News:Military Veterans Struck Down by Lou Gehrig's Disease Honored on Mother's Day by The ALS Association with Wreath Laying Ceremony at Arlington National Cemetery 2
(Date:10/22/2014)... 2014  Early symptoms of diabetic eye and ... new technology, coupled with yearly, comprehensive eye exams, ... detection of eye diseases, including those associated with ... left untreated, these diseases can potentially lead to ... Recently, optometric researchers have deployed a new tool ...
(Date:10/22/2014)... WESTMINSTER, Colo. , Oct. 22, 2014   ... class of infusion systems designed to maximize targeted delivery ... is pleased to announce that oncologist John R. ... Norris Comprehensive Cancer Center, and surgical oncologist Steven ... Center have joined the Company,s Scientific Advisory Board (SAB).  ...
(Date:10/22/2014)... VIEW, Calif. , Oct. 22, 2014 ... a.m. EDTLOCATION: Online, complimentary registration available at: ... Team Leader Archana Vidyasekar and Visionary Innovation ... computers, WiFi-like wireless electricity, self-assembling materials, nanobots ... ten technologies which will transform our lives ...
Breaking Medicine Technology:Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3Surefire Medical's Scientific Advisory Board Expands, Broadens Clinical Trial Expertise 2Futuristic Technologies That Will Transform Our World Beyond 2030 2Futuristic Technologies That Will Transform Our World Beyond 2030 3Futuristic Technologies That Will Transform Our World Beyond 2030 4
... committed to improving the health of its patients, workforce ... medical equipment to more eco-friendly alternatives that are free ... plastics that have been shown to harm human and ... purchase IV solution bags that are 100 percent PVC ...
... SHENZHEN, China, Jan. 19, 2012 /PRNewswire-Asia-FirstCall/ -- Mindray Medical ... developer, manufacturer and marketer of medical devices worldwide, today ... 2012 to be held between January 23 and 26 ... Health is the most important annual medical exhibition in ...
Cached Medicine Technology:Kaiser Permanente Moves to Green Medical Supplies by Converting to Eco-Friendly IV Equipment 2Kaiser Permanente Moves to Green Medical Supplies by Converting to Eco-Friendly IV Equipment 3Mindray Medical to Exhibit at Arab Health 2012 in Dubai from January 23-26 2
Angulated, blunt tips....
Autoclavable reusable pencil for Aaron 800 & 1200 - comes with generator or 1/box....
... All Bovie LLETZ Loop ... wire for superior shape and ... They use a standard 3/32" ... loops are packaged in a ...
7 1/2" Handswitch Monopolar Forceps, Ins., Curved, Serrated...
Medicine Products: