Navigation Links
Blood Pressure Drug Helps Those With Mild Heart Failure
Date:5/23/2011

SUNDAY, May 22 (HealthDay News) -- New Swedish research suggests that the drug Inspra reduces the threat of major cardiovascular complications among patients who have a mild form of heart failure.

This latest finding builds on earlier work that was published by the New England Journal of Medicine last fall. That study suggested that Inspra (eplerenone), an aldosterone antagonist, helps control cardiovascular complications among patients with a history of serious chronic heart failure.

Since far more people suffer from mild heart failure, this new finding could mean the drug might benefit a far broader group of patients, the researchers added.

The Swedish analysis makes an even stronger case for the use of Inspra in patients with mild heart failure because, in addition to reducing mortality, it also reduces the incidence of the irregular heart beat condition known as atrial fibrillation, study co-author Karl Swedberg, from the University of Gothenburg in Sweden, said in a news release from the European Society of Cardiology.

Atrial fibrillation "is a condition which both increases morbidity and complicates the care of patients with heart failure," he explained.

Swedberg and his colleagues were slated to present the findings Sunday in Gothenburg at the Heart Failure Congress 2011, organized by the Heart Failure Association of the European Society of Cardiology.

The study team noted that Inspra is currently approved for the control of high blood pressure as well as for the treatment of heart attack patients who experience congestive heart failure. It is not yet approved for the treatment of patients who experience mild heart failure. It is available generically in the United States, according to the news release.

Experts estimate that almost 6 million people in the United States suffer from heart failure.

The current finding stems from a re-analysis of a larger study that involved more than 2,700 heart failure patients being cared for at 278 different health centers.

Focusing specifically on those participants who had experienced mild (class 2) heart failure, the authors found that just 2.7 percent of those patients who were placed on a regimen of between 25 milligrams to 50 milligrams daily of Inspra for a little less than two years experienced atrial fibrillation.

This compared with 4.5 percent of those patients who were randomized to receive a sugar pill instead.

Dr. Byron K. Lee, director of the Electrophysiology Laboratories and Clinics within the division of cardiology at the University of California, San Francisco, noted that exactly how Inspra seems to help heart patients is not well understood.

"It is unclear how eplerenone works to lower the risk of abnormal heart rhythms like atrial fibrillation and atrial flutter," he said. "However, there are many potential mechanisms. One possibility is that eplerenone may help maintain potassium levels. Patients with heart failure are often on high-dose diuretics that remove fluid at the expense of removing potassium. Thats why heart failure patients need to watch their potassium level vigilantly."

More information

For more on atrial fibrillation, go to National Library of Medicine.

-- Alan Mozes

SOURCE: Byron K. Lee, M.D., director, Electrophysiology Laboratories and Clinics, division of cardiology, University of California, San Francisco; European Society of Cardiology, news release, May 22, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Psoriasis, High Blood Pressure May Be Linked
2. Research provides insight into quality of stored blood used for transfusions
3. Unnecessary Blood Tests Plunge After Cost Reminders: Study
4. Findings could lead to a blood test for lung cancer
5. Study reveals origins of a cancer affecting the blood and bone marrow
6. Chronic Tylenol Use May Be Linked to Blood Cancer, Study Suggests
7. Blood test for colon cancer screening beneficial for some seniors, but not for many others
8. Adalimumab levels detected in cord blood and infants exposed in utero
9. Blood Pressure May Hint at Kidney Cancer Outcome
10. Structured Exercise Programs Help Lower Blood Sugar, Study Finds
11. Religion Doesnt Help Lower Blood Pressure, Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blood Pressure Drug Helps Those With Mild Heart Failure
(Date:6/25/2016)... ... ... of Bruton Memorial Library on June 21 due to a possible lice infestation, as reported ... head lice: the parasite’s ability to live away from a human host, and to infest ... in the event that lice have simply gotten out of control. , As lice are ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and ... that call for a minimum wage raise to $12 an hour by 2020 and then ... will restore the lost value of the minimum wage, assure the wage floor does not ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... feeding the Frederick area economy by obtaining investment capital for emerging technology companies. ... 2½ years that have already resulted in more than a million dollars of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
Breaking Medicine Technology: