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Blood Cancer Advances May Improve Survival
Date:12/6/2010

vement in survival and well-being of patients with advances in therapy. And it's been known for some time that bisphosphonates have an effect not just on bone health but on the myeloma cells themselves," he noted.

"It's conceivable that different forms of bisphosphonates may have the same effect in terms of ameliorating bone disease but one may have a more suppressive effect on the myeloma cells," explained Lichtman, formerly executive vice president of research and medical programs for the Leukemia & Lymphoma Society. "So this study points to zoledronic acid as being more advantageous."

As for imatinib, the researchers "show impressive outcomes, and document striking differences in survival rates, that speak to the importance of using imatinib early," he said.

Because these studies were presented at a medical meeting, the findings should be viewed as preliminary until they are published in a peer-reviewed journal.

More information

For more on multiple myeloma, visit the Leukemia & Lymphoma Society.

-- Alan Mozes

SOURCES: Marshall Lichtman, M.D., professor of medicine and biochemistry and biophysics at the University of Rochester Medical Center, Rochester, N.Y.; news release, The Lancet, Dec. 4, 2010; news release, American Society of Hematology, Dec. 4, 2010


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