Navigation Links
Blocking Oncogene Can Stop Spread of Ovarian Cancer

Lab study showed it had effect on 60% Of malignant cells

MONDAY, Dec. 15 (HealthDay News) -- Blocking proteins produced by the oncogene MYC can stop the spread of ovarian cancer, researchers say.

An oncogene is a gene that has the potential to help cause cancer.

In up to 60 percent of human ovarian tumors, MYC is overly active. This causes the ovarian cells to produce excessive c-Myc, a protein regulator of other genes involved in cell growth, which leads to proliferation of the cancer cells.

University of California, Berkeley, researchers halted the spreading in lab cultures of human ovarian cancer cells with amplified MYC by using RNA interference (RNAi) to block c-Myc protein. They then used small interfering RNA (siRNA) to halt L-Myc and N-Myc proteins, a process that halted the growth of the non-amplified MYC tumors.

The therapies had no effect on lab cultures of normal ovarian surface epithelial cells, leading them to theorize that the RNAi and siRNA treatments are effective only when the MYC genes are abnormally active.

The findings are scheduled to be presented Monday at the American Society for Cell Biology annual meeting, in San Francisco.

More information

The National Ovarian Cancer Coalition has more about ovarian cancer.

-- Kevin McKeever

SOURCE: American Society for Cell Biology, news release, Dec. 14, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Blocking Potent Oxidant Could Prevent Morphine Tolerance
2. Blocking protein kills prostate cancer cells, inhibits tumor growth, Jefferson scientists find
3. Blocking the effect of inflammation-causing cells lowered prostate cancer cells invasion
4. Blocking signaling protein prevents prostate cancer spread, Jefferson scientists find
5. Pennsylvania Medical Society and AARP Criticize Senator Specter for Blocking Bill to Protect Access to Doctors and Improve Medicare
6. Blocking molecular pathway with whimsical name possible therapeutic target for pancreatic cancer
7. MicroRNA controls expression of oncogenes
8. Colon Cancer Oncogene Discovered
9. HIV denialists spread misinformation online -- consequences could be deadly; and more
10. Online Epidemic Gives Clues to Bird Flu Spread
11. Promising drug combination may help those with ocular melanoma that has spread
Post Your Comments:
Related Image:
Blocking Oncogene Can Stop Spread of Ovarian Cancer
(Date:10/13/2017)... Fort Worth, TX (PRWEB) , ... October 13, ... ... and financial planning agency serving communities in the greater Dallas, Miami, and Raleigh ... a young boy fighting to overcome a rare and deadly chromosome abnormality. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... The ... to promote standards of excellence for the field of eating disorders, announces the ... – 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... be giving viewers the lowdown on sciatica in a new episode of "Success ... focuses on current events and innovation and investigates each subject in-depth with passion ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated ... in breathing. Oral appliances can offer significant relief to about 75 percent of ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... Oct. 4, 2017  According to the Centers for Disease Control and ... October . PhysicianOne Urgent Care is helping communities across Massachusetts ... , by offering no-cost* flu shots through the end of the ... certain health insurance regulations. ... time to get a flu shot is by the end of October, ...
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
(Date:9/27/2017)... CAESAREA, Israel and NEW YORK , Sept. ... company with mobile health and big data solutions, today announced that its ... today. Please check your local TV listings for when The Dr. Oz ... ... ninth season this month. ...
Breaking Medicine Technology: