Navigation Links
Blocking Oncogene Can Stop Spread of Ovarian Cancer
Date:12/15/2008

Lab study showed it had effect on 60% Of malignant cells

MONDAY, Dec. 15 (HealthDay News) -- Blocking proteins produced by the oncogene MYC can stop the spread of ovarian cancer, researchers say.

An oncogene is a gene that has the potential to help cause cancer.

In up to 60 percent of human ovarian tumors, MYC is overly active. This causes the ovarian cells to produce excessive c-Myc, a protein regulator of other genes involved in cell growth, which leads to proliferation of the cancer cells.

University of California, Berkeley, researchers halted the spreading in lab cultures of human ovarian cancer cells with amplified MYC by using RNA interference (RNAi) to block c-Myc protein. They then used small interfering RNA (siRNA) to halt L-Myc and N-Myc proteins, a process that halted the growth of the non-amplified MYC tumors.

The therapies had no effect on lab cultures of normal ovarian surface epithelial cells, leading them to theorize that the RNAi and siRNA treatments are effective only when the MYC genes are abnormally active.

The findings are scheduled to be presented Monday at the American Society for Cell Biology annual meeting, in San Francisco.

More information

The National Ovarian Cancer Coalition has more about ovarian cancer.



-- Kevin McKeever



SOURCE: American Society for Cell Biology, news release, Dec. 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Blocking Potent Oxidant Could Prevent Morphine Tolerance
2. Blocking protein kills prostate cancer cells, inhibits tumor growth, Jefferson scientists find
3. Blocking the effect of inflammation-causing cells lowered prostate cancer cells invasion
4. Blocking signaling protein prevents prostate cancer spread, Jefferson scientists find
5. Pennsylvania Medical Society and AARP Criticize Senator Specter for Blocking Bill to Protect Access to Doctors and Improve Medicare
6. Blocking molecular pathway with whimsical name possible therapeutic target for pancreatic cancer
7. MicroRNA controls expression of oncogenes
8. Colon Cancer Oncogene Discovered
9. HIV denialists spread misinformation online -- consequences could be deadly; and more
10. Online Epidemic Gives Clues to Bird Flu Spread
11. Promising drug combination may help those with ocular melanoma that has spread
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blocking Oncogene Can Stop Spread of Ovarian Cancer
(Date:3/24/2017)... ... , ... Texas Physical Therapy Specialists (TexPTS) is pleased to announce the ... clinic is the group’s 7th location in San Antonio and 23rd in Texas. ... care from the clinic, which opened March 22, 2017. , The team ...
(Date:3/24/2017)... , ... March 24, 2017 , ... ... $100,000 for its innovative EcoQube Frame vertical micro-veggies garden on Kickstarter . ... for the product – with nearly 2,000 consumers (and counting) already backing the ...
(Date:3/24/2017)... ... , ... The law firm of Enea, Scanlan & Sirignano, LLP, ... Lauren C. Enea has joined the firm as an associate attorney. Ms. Enea, who ... elder law, Medicaid planning and applications, and Wills, Trusts and Estates. Samantha A. ...
(Date:3/24/2017)... ... 24, 2017 , ... Judy Buchanan, co-owner of Serenity Natural ... Judy says, “I am passionate about sharing Reiki as a holistic, complementary therapy ... challenging time.” , A Certified Medical Reiki™ Master trained by Raven Keys Medical ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The ... about real people of God in congregations across the United States. “The ... minister ordained in 1964 who has served congregations in seven states throughout his ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... and VANCOUVER, British Columbia , March ... SPHS ) (the "Company" or "Sophiris"), a clinical late-stage ... urological diseases, today announced that data from its successful ... as a focal treatment for localized prostate cancer, will ... at the 32 nd Annual European Association of ...
(Date:3/23/2017)... March 23, 2017  Ethicon* today announced the ... a privately held medical device company that manufactures ... the surgical treatment of Gastroesophageal Reflux Disease (GERD). ... expanding its portfolio of minimally invasive options for ... Financial terms of the transaction have not been ...
(Date:3/23/2017)... SILVER, N.J. , March 23, 2017 /PRNewswire/ ... company, today announced that it has kicked off ... into their 3D printed bone segments. ... Engineering, "Our unique variable honeycomb lattice structures have ... in-growth as compared to current allograft wedges from ...
Breaking Medicine Technology: