Navigation Links
Blinking neurons give thoughts away
Date:5/5/2010

Electrical currents are invisible to the naked eye at least they are when they flow through metal cables. In nerve cells, however, scientists are able to make electrical signals visible. Working with fellow experts from Switzerland and Japan, scientists from the Max Planck Institute for Medical Research in Heidelberg successfully used a specialized fluorescent protein to visualize electrical activity in neurons of living mice. In a milestone study, scientists are able to apply the method to watch activity in nerve cells during animal behaviour. (Frontiers in Neural Circuits, 29 April 2010)

Neurons communicate with one another via so-called action potentials. During an action potential, voltage-gated calcium channels are opened resulting in rapid calcium ion influx. Because of this tight coupling, fluorescent calcium indicator proteins can visualize action potentials. These proteins have two fluorescent subunits, one of which radiates yellow light and the other blue. When the proteins bind calcium, the proportion of yellow to blue light changes. Colour variation from blue light towards yellow thus reports different calcium levels which is why the protein has been dubbed a "cameleon".

Measuring action potentials optically

With the cameleon protein YC3.60, a fairly new variant, the scientists succeeded in recording the reaction of nerve cells to sensory stimuli in the intact brain of mice: every time the whiskers were deflected by a puff of air, there was a change of colour in the cameleon proteins in the nerve cells of the sensory areas of the cortex. It could therefore be deduced that the affected cells had reacted to the stimulus with action potentials. "The cameleon protein YC3.60 gives us the ability to measure action potentials not only in brain slices, but also in the intact brain. The molecule reacts quickly and sensitively and also captures changes in calcium concentrations occurring in rapid sequence," expla
'/>"/>

Contact: Mazahir T. Hasan
mazahir.hasan@mpimf-heidelberg.mpg.de
49-622-148-6617
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. New form of stem cell communication rescues diseased neurons
2. Stem Cells Become Functioning Neurons in Mice
3. Earlier bedtimes may help protect adolescents against depression and suicidal thoughts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blinking neurons give thoughts away
(Date:11/28/2014)... Dr. Paul Vitenas, one of the most awarded ... Holiday Event for those in the area that would like to ... & Glow will take place on December 11, 2014, from 6:00 ... heart of Houston at 4208 Richmond Ave. , “We want ... will come and celebrate the season with us on December 11, ...
(Date:11/28/2014)... Written and narrated by award winning author ... “The Happiest Man In the World: Life Lessons From ... and why Project C.U.R.E. came to be. , Raised in ... the Reverend Richard W. Jackson, Dr. Jackson exceeded his goal ... realized that he wasn’t happy. Prompted by this realization, James ...
(Date:11/28/2014)... Kramer HealthDay Reporter , THURSDAY, ... the kitchen, through cooking classes or at home, may make ... recent review. Cooking programs and classes for children seem ... the new research. And, although the review didn,t look at ... programs might help children develop long-lasting healthy habits. ...
(Date:11/28/2014)... An inventor and dental assistant from Kent, Wash., ... and it was almost impossible to reach. "This gave me ... , The patent-pending Access Light allows for easier use of ... the mouth, as well as avoids harm to the lips, ... use and clean, it also helps prevent cross-contamination. , The ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 More ... have now been filed in a New Jersey ... implants, Bernstein Liebhard LLP reports. , A ... County Superior Court reflects the filing of 2,160 ... hip stems, which were voluntarily recalled on July ...
Breaking Medicine News(10 mins):Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 2Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 3Health News:Thanksgiving Weekend Audiobook Treat! “The Happiest Man In the World: Life Lessons From a Cultural Economist” by Dr. James W. Jackson 2Health News:Want Kids to Eat Better? Get Them Cooking 2Health News:Want Kids to Eat Better? Get Them Cooking 3Health News:More than 2,100 Stryker Hip Lawsuits Included in New Jersey Litigation after Settlement Announcement, Bernstein Liebhard LLP Reports 2Health News:More than 2,100 Stryker Hip Lawsuits Included in New Jersey Litigation after Settlement Announcement, Bernstein Liebhard LLP Reports 3
... techniques, the Chinese Tai chi and various relaxation techniques would ... on May 28 by the Rajayoga Foundation of Brahmakumaris of ... of the Medical wing of the foundation and a ... of physical ailments by discovering the spiritual potential of the ...
... research conducted by the King’s Collage London, analysed health reports of ... in 2003 with those who took part// in the 1991 war, ... ,The study findings that are published in The Lancet report ... Syndrome" in British male armed forces personnel deployed to the 2003 ...
... government is planning to bifurcate the Health and Family ... Health Services//. This step is thought to allow for ... Welfare Minister R Ashok said that the step was ... abuse the system. Initially the government will ask 23 ...
... conducted by the rheumotologists in the University of South ... form of Adkins-type diet for weight loss, has no ... the earlier findings conducted in animal studies. This finding ... issue of the journal Osteoporosis International. Low carbohydrate diets ...
... least six Reang refugees staying in camps in North Tripura ... HIV positive, official sources today here said. // ... in Kanchanpur subdivision by the state health department., ,The ... were found affected by AIDS and 12 as HIV positive, ...
... Ltd today said it would raise 16 million dollar through ... ,The company would allot 16,000 FCCBs of 1,000 ... listed on the Singapore Stock Exchange, Ankur Drugs informed the ... would be allotted 14,000 FCCBs while 1,000 FCCBs would be ...
Cached Medicine News:Health News:Good News For The Obese People 2
(Date:11/26/2014)... 2014  Aethlon Medical, Inc. (OTCQB:AEMD), announced today that ... approximately $3.3 million at a price of $0.30 per ... focused investor. Each unit consists of one common share ... warrant. Each whole warrant entitles the holder to acquire ... a period of five years from closing.  ...
(Date:11/26/2014)...  Cohen, Placitella & Roth, PC is investigating ... Nymox Pharmaceutical Corporation ("Nymox" or "Company") (NASDAQ: ... 31, 2011 through November 2, 2014 ("Class Period").  ... its officers and directors publically disseminated materially false ... and 20(a) of the Securities Exchange Act of ...
(Date:11/26/2014)... Nov. 26, 2014 Lexicon Pharmaceuticals, Inc. ... completion of previously announced concurrent financing transactions resulting ... and estimated offering expenses, Lexicon anticipates net proceeds ... transactions consisted of: , a public ... to a registration statement that has been declared ...
Breaking Medicine Technology:Aethlon Medical Announces $3.3 Million Equity Investment 2Aethlon Medical Announces $3.3 Million Equity Investment 3Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 2Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 3Lexicon Announces Completion Of $280 Million In Financing Transactions 2Lexicon Announces Completion Of $280 Million In Financing Transactions 3
... 13-14, 2011, in Beijing, China, the Food and Drug Law ... drug law, regulation and policy in China and the United ... Commissioner, State Food and Drug Administration, Ambassador Zhang Yesui, Chinese ... at the meeting. Several U.S. government officials are expected to ...
... CHICAGO, Dec. 15, 2010 Allscripts MyWay ... -- deeming the Electronic Health Record (EHR) software capable ... use measures required to qualify for funding under the ... under the Drummond Group,s Electronic Health Records Office of ...
Cached Medicine Technology:Food and Drug Law Institute to Hold Historic Conference on U.S.-China Food and Drug Law 2Allscripts MyWay™ Electronic Health Record Receives ONC-ATCB Certification by Drummond Group 2Allscripts MyWay™ Electronic Health Record Receives ONC-ATCB Certification by Drummond Group 3Allscripts MyWay™ Electronic Health Record Receives ONC-ATCB Certification by Drummond Group 4Allscripts MyWay™ Electronic Health Record Receives ONC-ATCB Certification by Drummond Group 5
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 10.0 mm and length 10 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 8.0 mm and length 5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 8.0 mm and length 5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 10.0 mm and length 12 mm....
Medicine Products: