Navigation Links
Blind humans lacking rods and cones retain normal responses to non-visual effects of light
Date:12/13/2007

, the effect of light on melatonin secretion was examined. Melatonin is a hormone produced at night that influences arousal and is secreted in a cyclic fashion. Just like sighted individuals, the blind patient exhibited acute suppression of melatonin in response to light and was most sensitive to blue-light exposure.

Furthermore, blue light also shifted the timing of the circadian pacemaker and improved alertness, as measured by subjective scales, auditory reaction time, and changes in brain activity. While a few rods and/or cones may remain, Zaidi and colleagues have strong evidence to show that they contribute little, if at all, to these effects. Thus the authors were able to show that the effects were maximal in response to wavelengths of light that the retinal ganglion cells respond best to, and not the wavelength that the visual system detects best.

In the second patient, a different a set of tests was administered to assess the effects of light. First, the pupil-constriction response to various wavelengths and intensities of light was examined. Consistent with the major role of the pRGCs in mediating this response, pupillary contriction was stimulated most by blue light (~480 nm), the wavelength that pRGCs are most stimulated by.

Given that the non-visual responses to light appeared to be intact in this patient, the researchers were prompted to ask whether some minimal awareness of light might still be retained despite the inability to detect any response to light by conventional measures and the patients inability to see light. Remarkably, the patient was able to tell that the blue light, but not any other color, was switched on, demonstrating that the pRGCs also contribute to our ability to see light.

These results have a number of important implications for human vision and vision-related diseases. First, they suggest humans possess light-sensitive cells, apart from rods and cones, that are important for non-visual lig
'/>"/>

Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Can brain-injured, partially-blind stroke patients regain some of their lost vision?
2. New discovery may improve treatment of one of the worlds leading causes of blindness
3. Verizon Awards $1.5 Million Grant to Expand American Foundation for the Blinds Web Site for Seniors With Age-Related Vision Loss
4. Diabetes: A Top Cause of Blindness Among Adults
5. Blinded by the Light? Vision Problems and Visual Discomfort Make Driving in the Dark Difficult, Uncomfortable for Most Americans
6. Survey Confirms Americans Have a True Blind Spot Regarding Their Eye Health - and the Real Danger of UV Rays
7. STEP HIV vaccine study to be unblinded
8. Gene therapy safety trial for childhood blindness under way
9. National Federation of the Blind to Award $100,000
10. Investigational Agent Targeting Metabotropic Glutamate 2/3 Receptors Demonstrates Antipsychotic Activity in Humans, Study in Nature Medicine Finds
11. Toddler Study Proves Humans Outsmart Apes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... ... September 02, 2015 , ... ... large stream of mixed documents that include EOBs, payments, and payment related documents. ... the data needed to reconcile their billing, with one efficient process and interface,“ ...
(Date:9/2/2015)... Pittsburgh, PA (PRWEB) , ... September 02, 2015 ... ... the Health Sciences clinical and academic partnership has earned international recognition as a ... rare genetic disorder that can cause sudden, catastrophic internal bleeding and stroke. ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... largest and fastest-growing interim clinical staffing companies, has completed a recapitalization with ... , BPOC and Heritage Group each offer extensive expertise and ...
(Date:9/2/2015)... Kansas City, KS (PRWEB) , ... September 02, 2015 , ... ... recently opened its newest office in Kansas – its Johnson County location. ... backgrounds in healthcare. Mike has a registered nurse background and spent over 20 years ...
(Date:9/2/2015)... ... September 02, 2015 , ... Ovarian cancer continues to be ... risk of getting ovarian cancer in her lifetime is approximately 1 in 75. This ... ovarian cancer, and 14,000 will die. , There is no test to detect ...
Breaking Medicine News(10 mins):Health News:AliusDoc Launches Enhanced AD-EOB A/R Data Capture Solution to Streamline Processing of Payment-Related Documents Together with EOBs 2Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 2Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 3Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 4Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 2Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 3Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 4Health News:Amada Senior Care Expands to Greater Kansas City 2Health News:National Ovarian Cancer Coalition's DFW Chapter Features First Annual Teal Lights Display This Friday, September 4th, "National Wear Teal Day" 2Health News:National Ovarian Cancer Coalition's DFW Chapter Features First Annual Teal Lights Display This Friday, September 4th, "National Wear Teal Day" 3
... , , WASHINGTON, July 24 ... today in support of the minimum wage increase from $6.55 an hour ... minimum wage increase is an important step in recovering our economy, rebuilding ... it is only one of three prongs necessary to create a real ...
... common, but labeling is not required, report states , ... "enhance" uncooked meat and poultry can pose serious health ... Many fresh meat and poultry products are injected with ... not required to be listed on food labels, according ...
... , , CLEVELAND, July 24 /PRNewswire/ ... access for the uninsured and underinsured to a wide range of health ... 25 and 26, at the W.O. Walker Center, 10524 Euclid Ave. The ... provide 1100 medical, 300 vision and 200 dental patient visits. Appointments ...
... , CHICAGO, July 24 ... in designing and manufacturing portable rechargeable systems, today ... single-output power supplies. The new 350-watt series, designed ... delivers an industry-leading converter efficiency of up to ...
... WESTBROOK, Maine, July 24 IDEXX Laboratories, Inc. (Nasdaq: ... second quarter of 2009 were $265.7 million compared to $280.6 ... as defined below, was 5%. Earnings per diluted share ("EPS") ... to $0.63 for the same period in the prior year. ...
... ... Texans find affordable, direct access to medical lab testing through Any Lab Test Now®. , ... Plano, TX (PRWEB) July 24, 2009 -- This ... company has found its niche. Opened December 2008, Any Lab Test Now® in ...
Cached Medicine News:Health News:Fresh-Meat Additives May Be Dangerous for Kidney Patients 2Health News:U.S. Senator Sherrod Brown to Lend Support at MedWorks' Free Medical Clinic This Weekend 2Health News:Convection Cooled 350-Watt Open Frame Power Supply Meets Medical and Industrial Safety Standards 2Health News:IDEXX Laboratories Announces Second Quarter Results 2Health News:IDEXX Laboratories Announces Second Quarter Results 3Health News:IDEXX Laboratories Announces Second Quarter Results 4Health News:IDEXX Laboratories Announces Second Quarter Results 5Health News:IDEXX Laboratories Announces Second Quarter Results 6Health News:IDEXX Laboratories Announces Second Quarter Results 7Health News:IDEXX Laboratories Announces Second Quarter Results 8Health News:IDEXX Laboratories Announces Second Quarter Results 9Health News:IDEXX Laboratories Announces Second Quarter Results 10Health News:IDEXX Laboratories Announces Second Quarter Results 11Health News:IDEXX Laboratories Announces Second Quarter Results 12Health News:IDEXX Laboratories Announces Second Quarter Results 13Health News:IDEXX Laboratories Announces Second Quarter Results 14Health News:IDEXX Laboratories Announces Second Quarter Results 15Health News:IDEXX Laboratories Announces Second Quarter Results 16Health News:IDEXX Laboratories Announces Second Quarter Results 17Health News:IDEXX Laboratories Announces Second Quarter Results 18Health News:IDEXX Laboratories Announces Second Quarter Results 19Health News:IDEXX Laboratories Announces Second Quarter Results 20Health News:IDEXX Laboratories Announces Second Quarter Results 21Health News:IDEXX Laboratories Announces Second Quarter Results 22Health News:Cost-Conscious Texans Find Relief with Direct Access Lab Testing 2
(Date:9/2/2015)... , Sept. 2, 2015  Boca Raton ... FACS, has begun performing ultra-minimally invasive left atrial ... on anticoagulants such as Coumadin, Xarelto or Effient. ... at the Hospital, is one of a select ... involves making two microscopic incisions in order to ...
(Date:9/2/2015)... Medical, Inc. (Nasdaq: AEMD ), today announced that ... the Rodman & Renshaw 17th Annual Global Investment Conference in ... ET on Thursday, September 10, 2015. The presentation ... webcast which can be accessed by visiting the investor relations ... The webcast will be archived for thirty days.  ...
(Date:9/2/2015)... TORONTO , Sept. 2, ... ) (OTCQB: GNBT) today announced that its ... cannabis co-development arrangement with CannScience Innovations Inc. ... Generex and CannScience have entered into ... Pursuant to the Agreement, Generex has licensed ...
Breaking Medicine Technology:Boca Regional Introduces Ultra-Minimally Invasive Surgical Procedure for Atrial Fibrillation Patients 2Boca Regional Introduces Ultra-Minimally Invasive Surgical Procedure for Atrial Fibrillation Patients 3Generex Announces Formalization of Buccal Cannabis Co-Development Plan 2Generex Announces Formalization of Buccal Cannabis Co-Development Plan 3
... SANYO North America Corporation (SANYO) Biomedical Solutions Division ... integrated, stand-alone solution for GMP compliant processing and preparation ... use, has been installed at the University of Alabama ... the CPWS, as well as marking SANYO,s first to ...
... YORK, June 8, 2011 The winning products in this ... by UBM Canon , received their gold or silver ... Design & Manufacturing East (MD&M East) 2011 Conference and ... York City. (Logo: http://photos.prnewswire.com/prnh/20101214/LA16070LOGO ...
Cached Medicine Technology:SANYO Installs First Cell Processing Work Station in the United States at University of Alabama at Birmingham 2SANYO Installs First Cell Processing Work Station in the United States at University of Alabama at Birmingham 3Innovative Medical Products Showcased at MD&M East Ceremony 2Innovative Medical Products Showcased at MD&M East Ceremony 3Innovative Medical Products Showcased at MD&M East Ceremony 4
For accurately monitoring core temperature and heart and breath sounds as well as for gastric suctioning....
For accurately monitoring core temperature and heart and breath sounds....
... Level 1 enables hospitals ... patient monitors to a ... Our temperature monitoring disposale ... are superior in their ...
... Level 1 enables ... multiparameter patient monitors to ... series. Our temperature monitoring ... cables are superior in ...
Medicine Products: